PhD defence: Biomarkers of red meat intake: are we there yet?

Applications of untargeted metabolomics in the discovery and validation of biomarkers

Cătălina S. Cuparencu

PhD thesis

Biomarkers of meat intake may help clarify the controversial relationship between consumption of red meat and its effect on human health. This PhD project pays a close look at the development of biomarkers for intake of red meat by applying last-generation untargeted metabolomics techniques.

By investigating biological data collected in three human studies (2 cross-over controlled meal studies and a cross-sectional analysis of a lifestyle intervention study – the PREVIEW study), biomarkers of red meat intake are discovered and extensively validated according to published validation criteria.

The performance of single and combined biomarkers to predict meat intake is also thoroughly explored. The present thesis provides an overall evaluation of the status of biomarkers of red meat intake. Come and see!

2019, 275 pages.

Time

21 June 2019, 13:00

Place

Aud. A2-82.01, Thorvaldsensvej 40, Frederiksberg.

Opponents 

Professor Susanne Bügel, Department of Nutrition, Exercise and Sports, University of Copenhagen, Denmark.

Senior Researcher Augustin Scalbert, International Agency for Research on Cancer Lyon, France.

Professor Hanne Christine S. Bertram, Department of Food Science Aarhus University, Denmark.

Supervisor

Professor Lars Ove Dragsted, Department of Nutrition, Exercise and Sports, University of Copenhagen, Denmark.

Co-supervisors

Professor Anne Raben Department of Nutrition, Exercise and Sports, University of Copenhagen, Denmark.

Associate professor Åsmund Rinnan Department of Food Science, University of Copenhagen, Denmark.

The thesis is available for inspection at the library, Nørre Allé 51, DK-2200 Copenhagen N.