PhD defence: Regulation of TBC1D1 and TBC1D4 in skeletal muscle – From mouse to man

Christian Kirkegaard Pehmøller

PhD thesis

Regulation of the ability for skeletal muscle to take up glucose is essential for maintaining whole-body glucose homeostasis. These processes are facilitated by a fine-tuned orchestration of signaling events inside the skeletal muscle cell.

This PhD thesis investigates how two recently identified signaling molecules, involved in these processed, are regulated in transgenic animal models, a human model of acute insulin resistance and in people with type 2 diabetes.

2012, 124 pages, 100,- d.kr.
ISBN 978 87 917 71 49 1.

Time

20 September 2012 at 14:30

Venue

The Lundbeckfond Auditorium, Copenhagen Biocenter, Ole Maaløes Vej 5, Copenhagen

Opponents

Professor Ylva Hellsten (chair), Department of Exercise and Sport Sciences, University of Copenhagen, Denmark.

Associate Professor Niels Jessen, Aarhus University, Department of Clinical Medicine - MOMA, Denmark.

Doctor PhD Kei Sakamoto, Head of Diabetes, Nestlé Institute of Health Sciences SA, Switzerland.

Supervisor

Professor Jørgen Wojtaszewski, Department of Exercise and Sport Sciences, University of Copenhagen, Denmark.