Reduced lipid peroxidation in healthy subjects after supplementation with antioxidative nutrients in low doses

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Standard

Reduced lipid peroxidation in healthy subjects after supplementation with antioxidative nutrients in low doses. / Sjödin, Anders Mikael; Hambraeus, L; Jameson, S; Sjödin, B; Stålhammar, M; Vessby, B; Östman, B.

In: FASEB Journal, Vol. 10, No. 3, 1996, p. A821.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Harvard

Sjödin, AM, Hambraeus, L, Jameson, S, Sjödin, B, Stålhammar, M, Vessby, B & Östman, B 1996, 'Reduced lipid peroxidation in healthy subjects after supplementation with antioxidative nutrients in low doses', FASEB Journal, vol. 10, no. 3, pp. A821.

APA

Sjödin, A. M., Hambraeus, L., Jameson, S., Sjödin, B., Stålhammar, M., Vessby, B., & Östman, B. (1996). Reduced lipid peroxidation in healthy subjects after supplementation with antioxidative nutrients in low doses. FASEB Journal, 10(3), A821.

Vancouver

Sjödin AM, Hambraeus L, Jameson S, Sjödin B, Stålhammar M, Vessby B et al. Reduced lipid peroxidation in healthy subjects after supplementation with antioxidative nutrients in low doses. FASEB Journal. 1996;10(3):A821.

Author

Sjödin, Anders Mikael ; Hambraeus, L ; Jameson, S ; Sjödin, B ; Stålhammar, M ; Vessby, B ; Östman, B. / Reduced lipid peroxidation in healthy subjects after supplementation with antioxidative nutrients in low doses. In: FASEB Journal. 1996 ; Vol. 10, No. 3. pp. A821.

Bibtex

@article{31dd39abd4f04d32a8b15547290a083d,
title = "Reduced lipid peroxidation in healthy subjects after supplementation with antioxidative nutrients in low doses",
abstract = "Lipid peroxidation is a key event in the development of atherosclerotic lesions and there is a constant need for good tissue protection. Method: The effect of a 6 weeks supplementation with a juice fortified with α-tocopherol, ascorbic acid, β-carotene, Se and Zn (twice the RDI), compared with placebo, was studied in 36 healthy subjects in a double-blind manner. Plasma before and after therapy was analyzed for antioxidative capacity (AOC) and malone dialdehyde (MDA) as markers of antioxidant status and lipid peroxidation. Result: AOC increased by 19% after active therapy (309±79 vs. 259±54 μmol trolox eq l-1, p<0.05), but not after placebo (272±90 vs 277±61 μmol trolox eq. I-1). MDA decreased by 13% after supplementation (045-0.10 vs. 0.53-0.13 /jg I1, p<0.05), but not after the placebo period (0.55-0.14 vs. 0.52'0.13/jg -I1). Conclusion: The results support that a protective effect against lipid peroxidation can be achieved by supplementation with an antioxidant juice, in healthy subjects. This indicates that their habitual diet may contain suboptimal amounts of essential factors needed for tissue protection.",
author = "Sj{\"o}din, {Anders Mikael} and L Hambraeus and S Jameson and B Sj{\"o}din and M St{\aa}lhammar and B Vessby and B {\"O}stman",
year = "1996",
language = "English",
volume = "10",
pages = "A821",
journal = "F A S E B Journal",
issn = "0892-6638",
publisher = "Federation of American Societies for Experimental Biology",
number = "3",

}

RIS

TY - ABST

T1 - Reduced lipid peroxidation in healthy subjects after supplementation with antioxidative nutrients in low doses

AU - Sjödin, Anders Mikael

AU - Hambraeus, L

AU - Jameson, S

AU - Sjödin, B

AU - Stålhammar, M

AU - Vessby, B

AU - Östman, B

PY - 1996

Y1 - 1996

N2 - Lipid peroxidation is a key event in the development of atherosclerotic lesions and there is a constant need for good tissue protection. Method: The effect of a 6 weeks supplementation with a juice fortified with α-tocopherol, ascorbic acid, β-carotene, Se and Zn (twice the RDI), compared with placebo, was studied in 36 healthy subjects in a double-blind manner. Plasma before and after therapy was analyzed for antioxidative capacity (AOC) and malone dialdehyde (MDA) as markers of antioxidant status and lipid peroxidation. Result: AOC increased by 19% after active therapy (309±79 vs. 259±54 μmol trolox eq l-1, p<0.05), but not after placebo (272±90 vs 277±61 μmol trolox eq. I-1). MDA decreased by 13% after supplementation (045-0.10 vs. 0.53-0.13 /jg I1, p<0.05), but not after the placebo period (0.55-0.14 vs. 0.52'0.13/jg -I1). Conclusion: The results support that a protective effect against lipid peroxidation can be achieved by supplementation with an antioxidant juice, in healthy subjects. This indicates that their habitual diet may contain suboptimal amounts of essential factors needed for tissue protection.

AB - Lipid peroxidation is a key event in the development of atherosclerotic lesions and there is a constant need for good tissue protection. Method: The effect of a 6 weeks supplementation with a juice fortified with α-tocopherol, ascorbic acid, β-carotene, Se and Zn (twice the RDI), compared with placebo, was studied in 36 healthy subjects in a double-blind manner. Plasma before and after therapy was analyzed for antioxidative capacity (AOC) and malone dialdehyde (MDA) as markers of antioxidant status and lipid peroxidation. Result: AOC increased by 19% after active therapy (309±79 vs. 259±54 μmol trolox eq l-1, p<0.05), but not after placebo (272±90 vs 277±61 μmol trolox eq. I-1). MDA decreased by 13% after supplementation (045-0.10 vs. 0.53-0.13 /jg I1, p<0.05), but not after the placebo period (0.55-0.14 vs. 0.52'0.13/jg -I1). Conclusion: The results support that a protective effect against lipid peroxidation can be achieved by supplementation with an antioxidant juice, in healthy subjects. This indicates that their habitual diet may contain suboptimal amounts of essential factors needed for tissue protection.

UR - http://www.scopus.com/inward/record.url?scp=33749272528&partnerID=8YFLogxK

M3 - Conference abstract in journal

AN - SCOPUS:33749272528

VL - 10

SP - A821

JO - F A S E B Journal

JF - F A S E B Journal

SN - 0892-6638

IS - 3

ER -

ID: 211160791