Comparative molecular evolution of Trichoderma chitinases in response to mycoparasitic interactions

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Standard

Comparative molecular evolution of Trichoderma chitinases in response to mycoparasitic interactions. / Ihrmark, Katarina; Asmail, Nashwan; Ubhayasekera, Wimal; Melin, Petter; Stenlid, Jan; Karlsson, Magnus.

I: Evolutionary Bioinformatics Online, Bind 6, 15.03.2010, s. 1-26.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Ihrmark, K, Asmail, N, Ubhayasekera, W, Melin, P, Stenlid, J & Karlsson, M 2010, 'Comparative molecular evolution of Trichoderma chitinases in response to mycoparasitic interactions', Evolutionary Bioinformatics Online, bind 6, s. 1-26. https://doi.org/10.4137/EBO.S4198

APA

Ihrmark, K., Asmail, N., Ubhayasekera, W., Melin, P., Stenlid, J., & Karlsson, M. (2010). Comparative molecular evolution of Trichoderma chitinases in response to mycoparasitic interactions. Evolutionary Bioinformatics Online, 6, 1-26. https://doi.org/10.4137/EBO.S4198

Vancouver

Ihrmark K, Asmail N, Ubhayasekera W, Melin P, Stenlid J, Karlsson M. Comparative molecular evolution of Trichoderma chitinases in response to mycoparasitic interactions. Evolutionary Bioinformatics Online. 2010 mar 15;6:1-26. https://doi.org/10.4137/EBO.S4198

Author

Ihrmark, Katarina ; Asmail, Nashwan ; Ubhayasekera, Wimal ; Melin, Petter ; Stenlid, Jan ; Karlsson, Magnus. / Comparative molecular evolution of Trichoderma chitinases in response to mycoparasitic interactions. I: Evolutionary Bioinformatics Online. 2010 ; Bind 6. s. 1-26.

Bibtex

@article{1d1a834fbd284a888a47769be648dd45,
title = "Comparative molecular evolution of Trichoderma chitinases in response to mycoparasitic interactions",
abstract = "Certain species of the fungal genus Trichoderma are potent mycoparasites and are used for biological control of fungal diseases on agricultural crops. In Trichoderma, whole-genome sequencing reveal between 20 and 36 different genes encoding chitinases, hydrolytic enzymes that are involved in the mycoparasitic attack. Sequences of Trichoderma chitinase genes chi18-5, chi18-13, chi18-15 and chi18-17, which all exhibit specific expression during mycoparasitism-related conditions, were determined from up to 13 different taxa and studied with regard to their evolutionary patterns. Two of them, chi18-13 and chi18-17, are members of the B1/B2 chitinase subgroup that have expanded significantly in paralog number in mycoparasitic Hypocrea atroviridis and H. virens. Chi18-13 contains two codons that evolve under positive selection and seven groups of co-evolving sites. Chi18-15 displays a unique codon-usage and contains five codons that evolve under positive selection and three groups of co-evolving sites. Regions of high amino acid variability are preferentially localized to substrate- or product side of the catalytic clefts. Differences in amino acid diversity/conservation patterns between different Trichoderma clades are observed. These observations show that Trichoderma chitinases chi18-13 and chi18-15 evolve in a manner consistent with rapid co-evolutionary interactions and identifies putative target regions involved in determining substrate-specificity.",
keywords = "Former Faculty of Pharmaceutical Sciences",
author = "Katarina Ihrmark and Nashwan Asmail and Wimal Ubhayasekera and Petter Melin and Jan Stenlid and Magnus Karlsson",
note = "Keywords: protein evolution, Trichoderma, mycoparasitism, chitinase",
year = "2010",
month = "3",
day = "15",
doi = "10.4137/EBO.S4198",
language = "English",
volume = "6",
pages = "1--26",
journal = "Evolutionary Bioinformatics",
issn = "1176-9343",
publisher = "Libertas Academica Ltd.",

}

RIS

TY - JOUR

T1 - Comparative molecular evolution of Trichoderma chitinases in response to mycoparasitic interactions

AU - Ihrmark, Katarina

AU - Asmail, Nashwan

AU - Ubhayasekera, Wimal

AU - Melin, Petter

AU - Stenlid, Jan

AU - Karlsson, Magnus

N1 - Keywords: protein evolution, Trichoderma, mycoparasitism, chitinase

PY - 2010/3/15

Y1 - 2010/3/15

N2 - Certain species of the fungal genus Trichoderma are potent mycoparasites and are used for biological control of fungal diseases on agricultural crops. In Trichoderma, whole-genome sequencing reveal between 20 and 36 different genes encoding chitinases, hydrolytic enzymes that are involved in the mycoparasitic attack. Sequences of Trichoderma chitinase genes chi18-5, chi18-13, chi18-15 and chi18-17, which all exhibit specific expression during mycoparasitism-related conditions, were determined from up to 13 different taxa and studied with regard to their evolutionary patterns. Two of them, chi18-13 and chi18-17, are members of the B1/B2 chitinase subgroup that have expanded significantly in paralog number in mycoparasitic Hypocrea atroviridis and H. virens. Chi18-13 contains two codons that evolve under positive selection and seven groups of co-evolving sites. Chi18-15 displays a unique codon-usage and contains five codons that evolve under positive selection and three groups of co-evolving sites. Regions of high amino acid variability are preferentially localized to substrate- or product side of the catalytic clefts. Differences in amino acid diversity/conservation patterns between different Trichoderma clades are observed. These observations show that Trichoderma chitinases chi18-13 and chi18-15 evolve in a manner consistent with rapid co-evolutionary interactions and identifies putative target regions involved in determining substrate-specificity.

AB - Certain species of the fungal genus Trichoderma are potent mycoparasites and are used for biological control of fungal diseases on agricultural crops. In Trichoderma, whole-genome sequencing reveal between 20 and 36 different genes encoding chitinases, hydrolytic enzymes that are involved in the mycoparasitic attack. Sequences of Trichoderma chitinase genes chi18-5, chi18-13, chi18-15 and chi18-17, which all exhibit specific expression during mycoparasitism-related conditions, were determined from up to 13 different taxa and studied with regard to their evolutionary patterns. Two of them, chi18-13 and chi18-17, are members of the B1/B2 chitinase subgroup that have expanded significantly in paralog number in mycoparasitic Hypocrea atroviridis and H. virens. Chi18-13 contains two codons that evolve under positive selection and seven groups of co-evolving sites. Chi18-15 displays a unique codon-usage and contains five codons that evolve under positive selection and three groups of co-evolving sites. Regions of high amino acid variability are preferentially localized to substrate- or product side of the catalytic clefts. Differences in amino acid diversity/conservation patterns between different Trichoderma clades are observed. These observations show that Trichoderma chitinases chi18-13 and chi18-15 evolve in a manner consistent with rapid co-evolutionary interactions and identifies putative target regions involved in determining substrate-specificity.

KW - Former Faculty of Pharmaceutical Sciences

U2 - 10.4137/EBO.S4198

DO - 10.4137/EBO.S4198

M3 - Journal article

C2 - 20454524

VL - 6

SP - 1

EP - 26

JO - Evolutionary Bioinformatics

JF - Evolutionary Bioinformatics

SN - 1176-9343

ER -

ID: 33862610