Carboxylesterase 1 gene duplication and mRNA expression in adipose tissue are linked to obesity and metabolic function

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Standard

Carboxylesterase 1 gene duplication and mRNA expression in adipose tissue are linked to obesity and metabolic function. / Friedrichsen, Martin; Poulsen, Pernille; Wojtaszewski, Jørgen; Hansen, Peter Riis; Vaag, Allan; Rasmussen, Henrik Berg.

I: P L o S One, Bind 8, Nr. 2, 2013, s. e56861.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Friedrichsen, M, Poulsen, P, Wojtaszewski, J, Hansen, PR, Vaag, A & Rasmussen, HB 2013, 'Carboxylesterase 1 gene duplication and mRNA expression in adipose tissue are linked to obesity and metabolic function', P L o S One, bind 8, nr. 2, s. e56861. https://doi.org/10.1371/journal.pone.0056861

APA

Friedrichsen, M., Poulsen, P., Wojtaszewski, J., Hansen, P. R., Vaag, A., & Rasmussen, H. B. (2013). Carboxylesterase 1 gene duplication and mRNA expression in adipose tissue are linked to obesity and metabolic function. P L o S One, 8(2), e56861. https://doi.org/10.1371/journal.pone.0056861

Vancouver

Friedrichsen M, Poulsen P, Wojtaszewski J, Hansen PR, Vaag A, Rasmussen HB. Carboxylesterase 1 gene duplication and mRNA expression in adipose tissue are linked to obesity and metabolic function. P L o S One. 2013;8(2):e56861. https://doi.org/10.1371/journal.pone.0056861

Author

Friedrichsen, Martin ; Poulsen, Pernille ; Wojtaszewski, Jørgen ; Hansen, Peter Riis ; Vaag, Allan ; Rasmussen, Henrik Berg. / Carboxylesterase 1 gene duplication and mRNA expression in adipose tissue are linked to obesity and metabolic function. I: P L o S One. 2013 ; Bind 8, Nr. 2. s. e56861.

Bibtex

@article{8e9253078c764cddb1a085424ff00917,
title = "Carboxylesterase 1 gene duplication and mRNA expression in adipose tissue are linked to obesity and metabolic function",
abstract = "CONTEXT AND AIMS: Carboxylesterase 1 (CES1) appears to play an important role in the control of the metabolism of triglycerides and cholesterol in adipocytes and other cell types including hepatocytes. Therefore, it is relevant to gain insights into the genetic versus non-genetic mechanisms involved in the control of mRNA expression. Here, we investigated mRNA expression level in adipose tissue and its association with measures of adiposity and metabolic function in a population of elderly twins. Furthermore, the heritability of mRNA expression level in adipose tissue and the effect of gene duplication were assessed.",
author = "Martin Friedrichsen and Pernille Poulsen and J{\o}rgen Wojtaszewski and Hansen, {Peter Riis} and Allan Vaag and Rasmussen, {Henrik Berg}",
note = "OA",
year = "2013",
doi = "10.1371/journal.pone.0056861",
language = "English",
volume = "8",
pages = "e56861",
journal = "P L o S One",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "2",

}

RIS

TY - JOUR

T1 - Carboxylesterase 1 gene duplication and mRNA expression in adipose tissue are linked to obesity and metabolic function

AU - Friedrichsen, Martin

AU - Poulsen, Pernille

AU - Wojtaszewski, Jørgen

AU - Hansen, Peter Riis

AU - Vaag, Allan

AU - Rasmussen, Henrik Berg

N1 - OA

PY - 2013

Y1 - 2013

N2 - CONTEXT AND AIMS: Carboxylesterase 1 (CES1) appears to play an important role in the control of the metabolism of triglycerides and cholesterol in adipocytes and other cell types including hepatocytes. Therefore, it is relevant to gain insights into the genetic versus non-genetic mechanisms involved in the control of mRNA expression. Here, we investigated mRNA expression level in adipose tissue and its association with measures of adiposity and metabolic function in a population of elderly twins. Furthermore, the heritability of mRNA expression level in adipose tissue and the effect of gene duplication were assessed.

AB - CONTEXT AND AIMS: Carboxylesterase 1 (CES1) appears to play an important role in the control of the metabolism of triglycerides and cholesterol in adipocytes and other cell types including hepatocytes. Therefore, it is relevant to gain insights into the genetic versus non-genetic mechanisms involved in the control of mRNA expression. Here, we investigated mRNA expression level in adipose tissue and its association with measures of adiposity and metabolic function in a population of elderly twins. Furthermore, the heritability of mRNA expression level in adipose tissue and the effect of gene duplication were assessed.

U2 - 10.1371/journal.pone.0056861

DO - 10.1371/journal.pone.0056861

M3 - Journal article

C2 - 23468884

VL - 8

SP - e56861

JO - P L o S One

JF - P L o S One

SN - 1932-6203

IS - 2

ER -

ID: 44882281