Measuring growth and medium- and longer-term outcomes in malnourished children

Publikation: Bidrag til tidsskriftReviewfagfællebedømt

Standard

Measuring growth and medium- and longer-term outcomes in malnourished children. / Owino, Victor O; Murphy-Alford, Alexia J; Kerac, Marko; Bahwere, Paluku; Friis, Henrik; Berkley, James A; Jackson, Alan A.

I: Maternal and Child Nutrition, Bind 15, Nr. 3, e12790, 2019.

Publikation: Bidrag til tidsskriftReviewfagfællebedømt

Harvard

Owino, VO, Murphy-Alford, AJ, Kerac, M, Bahwere, P, Friis, H, Berkley, JA & Jackson, AA 2019, 'Measuring growth and medium- and longer-term outcomes in malnourished children', Maternal and Child Nutrition, bind 15, nr. 3, e12790. https://doi.org/10.1111/mcn.12790

APA

Owino, V. O., Murphy-Alford, A. J., Kerac, M., Bahwere, P., Friis, H., Berkley, J. A., & Jackson, A. A. (2019). Measuring growth and medium- and longer-term outcomes in malnourished children. Maternal and Child Nutrition, 15(3), [e12790]. https://doi.org/10.1111/mcn.12790

Vancouver

Owino VO, Murphy-Alford AJ, Kerac M, Bahwere P, Friis H, Berkley JA o.a. Measuring growth and medium- and longer-term outcomes in malnourished children. Maternal and Child Nutrition. 2019;15(3). e12790. https://doi.org/10.1111/mcn.12790

Author

Owino, Victor O ; Murphy-Alford, Alexia J ; Kerac, Marko ; Bahwere, Paluku ; Friis, Henrik ; Berkley, James A ; Jackson, Alan A. / Measuring growth and medium- and longer-term outcomes in malnourished children. I: Maternal and Child Nutrition. 2019 ; Bind 15, Nr. 3.

Bibtex

@article{436c1450aaac45fba354368a371c4ff3,
title = "Measuring growth and medium- and longer-term outcomes in malnourished children",
abstract = "Severe and moderate acute malnutrition are among the leading causes of mortality among children in low- and middle-income countries. There is strong evidence that growth assessed anthropometrically from conception to 2 years of age marks later risk of ill-health. This is central to the concept of the developmental origins of adult disease and is presumed to be related to modification of developmental processes during critical {"}window(s){"} of vulnerability. Interventions to treat acute malnutrition have resulted in dramatic increase in the number of affected children surviving. Ensuring that these children thrive to fulfil their full physical and cognitive potential is a new challenge. Integral to this challenge is the need to be able to measure how earlier insults relate to the ability to survive and thrive to productive adulthood. Despite its obvious value, routine anthropometry does not adequately indicate how earlier adverse exposures affect more refined aspects of growth. Anthropometry is inadequate for predicting how disruption of healthy growth might modulate risk of disease, or any subsequent interventions correct this risk. A clear characterisation of healthy child growth is needed for determining which component best predicts later outcomes. The extent to which postnatal acute malnutrition is a consequence of maternal factors acting pre-conception or in-utero and their relationship to postnatal health and long-term risk of non-communicable diseases is not clear. Body composition measurement has significant untapped potential allowing us to translate and better understand the relationship between early insults and interventions on early growth in the short-term and long-term health outcomes.",
keywords = "Faculty of Science, Growth, Acute malnutrition, DoHaD, Body composition, Assessment of nutritional status, Chronic disease",
author = "Owino, {Victor O} and Murphy-Alford, {Alexia J} and Marko Kerac and Paluku Bahwere and Henrik Friis and Berkley, {James A} and Jackson, {Alan A}",
note = "CURIS 2019 NEXS 079",
year = "2019",
doi = "10.1111/mcn.12790",
language = "English",
volume = "15",
journal = "Maternal and Child Nutrition",
issn = "1740-8695",
publisher = "Wiley-Blackwell",
number = "3",

}

RIS

TY - JOUR

T1 - Measuring growth and medium- and longer-term outcomes in malnourished children

AU - Owino, Victor O

AU - Murphy-Alford, Alexia J

AU - Kerac, Marko

AU - Bahwere, Paluku

AU - Friis, Henrik

AU - Berkley, James A

AU - Jackson, Alan A

N1 - CURIS 2019 NEXS 079

PY - 2019

Y1 - 2019

N2 - Severe and moderate acute malnutrition are among the leading causes of mortality among children in low- and middle-income countries. There is strong evidence that growth assessed anthropometrically from conception to 2 years of age marks later risk of ill-health. This is central to the concept of the developmental origins of adult disease and is presumed to be related to modification of developmental processes during critical "window(s)" of vulnerability. Interventions to treat acute malnutrition have resulted in dramatic increase in the number of affected children surviving. Ensuring that these children thrive to fulfil their full physical and cognitive potential is a new challenge. Integral to this challenge is the need to be able to measure how earlier insults relate to the ability to survive and thrive to productive adulthood. Despite its obvious value, routine anthropometry does not adequately indicate how earlier adverse exposures affect more refined aspects of growth. Anthropometry is inadequate for predicting how disruption of healthy growth might modulate risk of disease, or any subsequent interventions correct this risk. A clear characterisation of healthy child growth is needed for determining which component best predicts later outcomes. The extent to which postnatal acute malnutrition is a consequence of maternal factors acting pre-conception or in-utero and their relationship to postnatal health and long-term risk of non-communicable diseases is not clear. Body composition measurement has significant untapped potential allowing us to translate and better understand the relationship between early insults and interventions on early growth in the short-term and long-term health outcomes.

AB - Severe and moderate acute malnutrition are among the leading causes of mortality among children in low- and middle-income countries. There is strong evidence that growth assessed anthropometrically from conception to 2 years of age marks later risk of ill-health. This is central to the concept of the developmental origins of adult disease and is presumed to be related to modification of developmental processes during critical "window(s)" of vulnerability. Interventions to treat acute malnutrition have resulted in dramatic increase in the number of affected children surviving. Ensuring that these children thrive to fulfil their full physical and cognitive potential is a new challenge. Integral to this challenge is the need to be able to measure how earlier insults relate to the ability to survive and thrive to productive adulthood. Despite its obvious value, routine anthropometry does not adequately indicate how earlier adverse exposures affect more refined aspects of growth. Anthropometry is inadequate for predicting how disruption of healthy growth might modulate risk of disease, or any subsequent interventions correct this risk. A clear characterisation of healthy child growth is needed for determining which component best predicts later outcomes. The extent to which postnatal acute malnutrition is a consequence of maternal factors acting pre-conception or in-utero and their relationship to postnatal health and long-term risk of non-communicable diseases is not clear. Body composition measurement has significant untapped potential allowing us to translate and better understand the relationship between early insults and interventions on early growth in the short-term and long-term health outcomes.

KW - Faculty of Science

KW - Growth

KW - Acute malnutrition

KW - DoHaD

KW - Body composition

KW - Assessment of nutritional status

KW - Chronic disease

U2 - 10.1111/mcn.12790

DO - 10.1111/mcn.12790

M3 - Review

C2 - 30690903

VL - 15

JO - Maternal and Child Nutrition

JF - Maternal and Child Nutrition

SN - 1740-8695

IS - 3

M1 - e12790

ER -

ID: 212906075