Cohort Profile: Design and methods of the PREDIMED-Plus randomized trial

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

PREDIMED-Plus Investigators

The rationale for a new randomized trial (‘PREDIMEDPlus’) is to go beyond the previous PREDIMED trial, and to answer one of the most important questions in current medical practice: is an intentional body mass reduction through PA promotion and energy reduction, able to bring about in the long term a substantial reduction in hard cardiovascular clinical events? Our main hypothesis is that by addressing three lifestyle aspects (energy reduction with a high-quality
dietary pattern, recommendations on PA and motivational behaviour changes, based on providing persuasion and tools for solving problems, potentially derived from avoiding high calorie foods and sedentary lifestyles), an even stronger reduction in the risk of hard cardiovascular events will be attained, as compared with that observed with only a MedDiet.
OriginalsprogEngelsk
TidsskriftInternational Journal of Epidemiology
Vol/bind48
Udgave nummer2
Sider (fra-til)387-388o
Antal sider17
ISSN0300-5771
DOI
StatusUdgivet - 2019

Bibliografisk note

CURIS 2019 NEXS 259
Arne Astrup is a member of the Independent Data and Safety Monitoring Board of the PREDIMED-Plus Investigators.

ID: 225834338