Species-specific associations between soil-transmitted helminths and micronutrients in Vietnamese schoolchildren

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Species-specific associations between soil-transmitted helminths and micronutrients in Vietnamese schoolchildren. / de Gier, Brechje; Nga, Tran Thuy; Winichagoon, Pattanee; Dijkhuizen, Marjoleine Amma; Khan, Nguyen Cong; van de Bor, Margot; Ponce, Maiza Campos; Polman, Katja; Wieringa, Frank T.

I: American Journal of Tropical Medicine and Hygiene, Bind 95, Nr. 1, 06.07.2016, s. 77-82.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

de Gier, B, Nga, TT, Winichagoon, P, Dijkhuizen, MA, Khan, NC, van de Bor, M, Ponce, MC, Polman, K & Wieringa, FT 2016, 'Species-specific associations between soil-transmitted helminths and micronutrients in Vietnamese schoolchildren', American Journal of Tropical Medicine and Hygiene, bind 95, nr. 1, s. 77-82. https://doi.org/10.4269/ajtmh.15-0533

APA

de Gier, B., Nga, T. T., Winichagoon, P., Dijkhuizen, M. A., Khan, N. C., van de Bor, M., ... Wieringa, F. T. (2016). Species-specific associations between soil-transmitted helminths and micronutrients in Vietnamese schoolchildren. American Journal of Tropical Medicine and Hygiene, 95(1), 77-82. https://doi.org/10.4269/ajtmh.15-0533

Vancouver

de Gier B, Nga TT, Winichagoon P, Dijkhuizen MA, Khan NC, van de Bor M o.a. Species-specific associations between soil-transmitted helminths and micronutrients in Vietnamese schoolchildren. American Journal of Tropical Medicine and Hygiene. 2016 jul 6;95(1):77-82. https://doi.org/10.4269/ajtmh.15-0533

Author

de Gier, Brechje ; Nga, Tran Thuy ; Winichagoon, Pattanee ; Dijkhuizen, Marjoleine Amma ; Khan, Nguyen Cong ; van de Bor, Margot ; Ponce, Maiza Campos ; Polman, Katja ; Wieringa, Frank T. / Species-specific associations between soil-transmitted helminths and micronutrients in Vietnamese schoolchildren. I: American Journal of Tropical Medicine and Hygiene. 2016 ; Bind 95, Nr. 1. s. 77-82.

Bibtex

@article{5effce83c92942568372e57f0f527e33,
title = "Species-specific associations between soil-transmitted helminths and micronutrients in Vietnamese schoolchildren",
abstract = "Soil-transmitted helminth (STH) infections and micronutrient deficiencies are closely related and often coexist among low-income populations. We studied the association between infections with specific STH species and micronutrient status in rural Vietnamese schoolchildren. Children (N = 510) aged 6-9 years were recruited from two primary schools. STH infections were determined in stool samples. Hemoglobin, ferritin, retinol, and zinc were measured in blood samples, as well as C-reactive protein to control for inflammation. Iodine excretion was measured in urine. Associations of single and multiple infections with Ascaris lumbricoides, Trichuris trichiura, and hookworm with micronutrient status (hemoglobin, plasma ferritin, retinol, zinc, and urinary iodine) were estimated by multiple regression analysis. Ascaris infections showed a specific and intensity-dependent negative association with vitamin A. Trichuris and hookworm infections were associated with lower hemoglobin concentration, but not with plasma ferritin. Trichuris-infected children had zinc deficiency less often than uninfected children. In conclusion, our study shows species-specific associations between STH infections and micronutrient status in children. The different life cycles of STH species might have specific effects on the absorption or loss of specific micronutrients. Tailor-made combinations of deworming and nutritional interventions may be needed to improve child health and nutrition.",
keywords = "Ancylostomatoidea, Animals, Ascariasis, Ascaris lumbricoides, C-Reactive Protein, Child, Cross-Sectional Studies, Feces, Female, Ferritins, Hemoglobins, Hookworm Infections, Humans, Iodine, Male, Malnutrition, Micronutrients, Prevalence, Rural Population, Soil, Species Specificity, Trichuriasis, Trichuris, Vietnam, Vitamin A, Zinc, Journal Article",
author = "{de Gier}, Brechje and Nga, {Tran Thuy} and Pattanee Winichagoon and Dijkhuizen, {Marjoleine Amma} and Khan, {Nguyen Cong} and {van de Bor}, Margot and Ponce, {Maiza Campos} and Katja Polman and Wieringa, {Frank T.}",
note = "CURIS 2016 NEXS 396",
year = "2016",
month = "7",
day = "6",
doi = "10.4269/ajtmh.15-0533",
language = "English",
volume = "95",
pages = "77--82",
journal = "American Journal of Tropical Medicine and Hygiene",
issn = "0002-9637",
publisher = "American Society of Tropical Medicine and Hygiene",
number = "1",

}

RIS

TY - JOUR

T1 - Species-specific associations between soil-transmitted helminths and micronutrients in Vietnamese schoolchildren

AU - de Gier, Brechje

AU - Nga, Tran Thuy

AU - Winichagoon, Pattanee

AU - Dijkhuizen, Marjoleine Amma

AU - Khan, Nguyen Cong

AU - van de Bor, Margot

AU - Ponce, Maiza Campos

AU - Polman, Katja

AU - Wieringa, Frank T.

N1 - CURIS 2016 NEXS 396

PY - 2016/7/6

Y1 - 2016/7/6

N2 - Soil-transmitted helminth (STH) infections and micronutrient deficiencies are closely related and often coexist among low-income populations. We studied the association between infections with specific STH species and micronutrient status in rural Vietnamese schoolchildren. Children (N = 510) aged 6-9 years were recruited from two primary schools. STH infections were determined in stool samples. Hemoglobin, ferritin, retinol, and zinc were measured in blood samples, as well as C-reactive protein to control for inflammation. Iodine excretion was measured in urine. Associations of single and multiple infections with Ascaris lumbricoides, Trichuris trichiura, and hookworm with micronutrient status (hemoglobin, plasma ferritin, retinol, zinc, and urinary iodine) were estimated by multiple regression analysis. Ascaris infections showed a specific and intensity-dependent negative association with vitamin A. Trichuris and hookworm infections were associated with lower hemoglobin concentration, but not with plasma ferritin. Trichuris-infected children had zinc deficiency less often than uninfected children. In conclusion, our study shows species-specific associations between STH infections and micronutrient status in children. The different life cycles of STH species might have specific effects on the absorption or loss of specific micronutrients. Tailor-made combinations of deworming and nutritional interventions may be needed to improve child health and nutrition.

AB - Soil-transmitted helminth (STH) infections and micronutrient deficiencies are closely related and often coexist among low-income populations. We studied the association between infections with specific STH species and micronutrient status in rural Vietnamese schoolchildren. Children (N = 510) aged 6-9 years were recruited from two primary schools. STH infections were determined in stool samples. Hemoglobin, ferritin, retinol, and zinc were measured in blood samples, as well as C-reactive protein to control for inflammation. Iodine excretion was measured in urine. Associations of single and multiple infections with Ascaris lumbricoides, Trichuris trichiura, and hookworm with micronutrient status (hemoglobin, plasma ferritin, retinol, zinc, and urinary iodine) were estimated by multiple regression analysis. Ascaris infections showed a specific and intensity-dependent negative association with vitamin A. Trichuris and hookworm infections were associated with lower hemoglobin concentration, but not with plasma ferritin. Trichuris-infected children had zinc deficiency less often than uninfected children. In conclusion, our study shows species-specific associations between STH infections and micronutrient status in children. The different life cycles of STH species might have specific effects on the absorption or loss of specific micronutrients. Tailor-made combinations of deworming and nutritional interventions may be needed to improve child health and nutrition.

KW - Ancylostomatoidea

KW - Animals

KW - Ascariasis

KW - Ascaris lumbricoides

KW - C-Reactive Protein

KW - Child

KW - Cross-Sectional Studies

KW - Feces

KW - Female

KW - Ferritins

KW - Hemoglobins

KW - Hookworm Infections

KW - Humans

KW - Iodine

KW - Male

KW - Malnutrition

KW - Micronutrients

KW - Prevalence

KW - Rural Population

KW - Soil

KW - Species Specificity

KW - Trichuriasis

KW - Trichuris

KW - Vietnam

KW - Vitamin A

KW - Zinc

KW - Journal Article

U2 - 10.4269/ajtmh.15-0533

DO - 10.4269/ajtmh.15-0533

M3 - Journal article

C2 - 27246448

VL - 95

SP - 77

EP - 82

JO - American Journal of Tropical Medicine and Hygiene

JF - American Journal of Tropical Medicine and Hygiene

SN - 0002-9637

IS - 1

ER -

ID: 178988243