Optimal screening of children with acute malnutrition requires a change in current WHO guidelines as MUAC and WHZ identify different patient groups

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Optimal screening of children with acute malnutrition requires a change in current WHO guidelines as MUAC and WHZ identify different patient groups. / Laillou, Arnaud; Prak, Sophonneary; de Groot, Richard; Whitney, Sophie; Conkle, Joel; Horton, Lindsey; Un, Sam Oeurn; Dijkhuizen, Marjoleine Amma; Wieringa, Frank T.

I: P L o S One, Bind 9, Nr. 7, e101159, 2014.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Laillou, A, Prak, S, de Groot, R, Whitney, S, Conkle, J, Horton, L, Un, SO, Dijkhuizen, MA & Wieringa, FT 2014, 'Optimal screening of children with acute malnutrition requires a change in current WHO guidelines as MUAC and WHZ identify different patient groups', P L o S One, bind 9, nr. 7, e101159. https://doi.org/10.1371/journal.pone.0101159

APA

Laillou, A., Prak, S., de Groot, R., Whitney, S., Conkle, J., Horton, L., ... Wieringa, F. T. (2014). Optimal screening of children with acute malnutrition requires a change in current WHO guidelines as MUAC and WHZ identify different patient groups. P L o S One, 9(7), [e101159]. https://doi.org/10.1371/journal.pone.0101159

Vancouver

Laillou A, Prak S, de Groot R, Whitney S, Conkle J, Horton L o.a. Optimal screening of children with acute malnutrition requires a change in current WHO guidelines as MUAC and WHZ identify different patient groups. P L o S One. 2014;9(7). e101159. https://doi.org/10.1371/journal.pone.0101159

Author

Laillou, Arnaud ; Prak, Sophonneary ; de Groot, Richard ; Whitney, Sophie ; Conkle, Joel ; Horton, Lindsey ; Un, Sam Oeurn ; Dijkhuizen, Marjoleine Amma ; Wieringa, Frank T. / Optimal screening of children with acute malnutrition requires a change in current WHO guidelines as MUAC and WHZ identify different patient groups. I: P L o S One. 2014 ; Bind 9, Nr. 7.

Bibtex

@article{a8c6e8c1d3e14c3480cc8f91a1363cae,
title = "Optimal screening of children with acute malnutrition requires a change in current WHO guidelines as MUAC and WHZ identify different patient groups",
abstract = "BACKGROUND: Timely treatment of acute malnutrition in children <5 age could of prevent years>500,000 deaths annually. Screening at community level is essential to identify children with malnutrition. Current WHO guidelines for community screening for malnutrition recommend a Mid Upper Arm Circumference (MUAC) of <115 (sam). (whz).methods: acute currently data define from how however, identify indicator is it malnutrition malnutrition: mm muac other relates secondary severe the to unclear used weight-for-height z-score>11,000 Cambodian children, obtained by different surveys between 2010 and 2012, was used to calculate sensitivity and ROC curves for MUAC and WHZ.FINDINGS: The secondary analysis showed that using the current WHO cut-off of 115 mm for screening for severe acute malnutrition over 90{\%} of children with a weight-for-height z-score (WHZ) <-3 would have been missed. Reversely, WHZ<-3 missed 80{\%} of the children with a MUAC<115 115 133 a allow be cambodian changed current cut-off data-set, for from in inclusion mm mm. mm.conclusions: of sam screening should the upwards who would>65{\%} of children with a WHZ<-3. Importantly, MUAC and WHZ identified different sub-groups of children with acute malnutrition, therefore these 2 indicators should be regarded as independent from each other. We suggest a 2-step model with MUAC used a screening at community level, followed by MUAC and WHZ measured at a primary health care unit, with both indicators used independently to diagnose severe acute malnutrition. Current guidelines should be changed to reflect this, with treatment initiated when either MUAC <115 mm or WHZ<-3.",
author = "Arnaud Laillou and Sophonneary Prak and {de Groot}, Richard and Sophie Whitney and Joel Conkle and Lindsey Horton and Un, {Sam Oeurn} and Dijkhuizen, {Marjoleine Amma} and Wieringa, {Frank T}",
note = "CURIS 2014 NEXS 416",
year = "2014",
doi = "10.1371/journal.pone.0101159",
language = "English",
volume = "9",
journal = "P L o S One",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "7",

}

RIS

TY - JOUR

T1 - Optimal screening of children with acute malnutrition requires a change in current WHO guidelines as MUAC and WHZ identify different patient groups

AU - Laillou, Arnaud

AU - Prak, Sophonneary

AU - de Groot, Richard

AU - Whitney, Sophie

AU - Conkle, Joel

AU - Horton, Lindsey

AU - Un, Sam Oeurn

AU - Dijkhuizen, Marjoleine Amma

AU - Wieringa, Frank T

N1 - CURIS 2014 NEXS 416

PY - 2014

Y1 - 2014

N2 - BACKGROUND: Timely treatment of acute malnutrition in children <5 age could of prevent years>500,000 deaths annually. Screening at community level is essential to identify children with malnutrition. Current WHO guidelines for community screening for malnutrition recommend a Mid Upper Arm Circumference (MUAC) of <115 (sam). (whz).methods: acute currently data define from how however, identify indicator is it malnutrition malnutrition: mm muac other relates secondary severe the to unclear used weight-for-height z-score>11,000 Cambodian children, obtained by different surveys between 2010 and 2012, was used to calculate sensitivity and ROC curves for MUAC and WHZ.FINDINGS: The secondary analysis showed that using the current WHO cut-off of 115 mm for screening for severe acute malnutrition over 90% of children with a weight-for-height z-score (WHZ) <-3 would have been missed. Reversely, WHZ<-3 missed 80% of the children with a MUAC<115 115 133 a allow be cambodian changed current cut-off data-set, for from in inclusion mm mm. mm.conclusions: of sam screening should the upwards who would>65% of children with a WHZ<-3. Importantly, MUAC and WHZ identified different sub-groups of children with acute malnutrition, therefore these 2 indicators should be regarded as independent from each other. We suggest a 2-step model with MUAC used a screening at community level, followed by MUAC and WHZ measured at a primary health care unit, with both indicators used independently to diagnose severe acute malnutrition. Current guidelines should be changed to reflect this, with treatment initiated when either MUAC <115 mm or WHZ<-3.

AB - BACKGROUND: Timely treatment of acute malnutrition in children <5 age could of prevent years>500,000 deaths annually. Screening at community level is essential to identify children with malnutrition. Current WHO guidelines for community screening for malnutrition recommend a Mid Upper Arm Circumference (MUAC) of <115 (sam). (whz).methods: acute currently data define from how however, identify indicator is it malnutrition malnutrition: mm muac other relates secondary severe the to unclear used weight-for-height z-score>11,000 Cambodian children, obtained by different surveys between 2010 and 2012, was used to calculate sensitivity and ROC curves for MUAC and WHZ.FINDINGS: The secondary analysis showed that using the current WHO cut-off of 115 mm for screening for severe acute malnutrition over 90% of children with a weight-for-height z-score (WHZ) <-3 would have been missed. Reversely, WHZ<-3 missed 80% of the children with a MUAC<115 115 133 a allow be cambodian changed current cut-off data-set, for from in inclusion mm mm. mm.conclusions: of sam screening should the upwards who would>65% of children with a WHZ<-3. Importantly, MUAC and WHZ identified different sub-groups of children with acute malnutrition, therefore these 2 indicators should be regarded as independent from each other. We suggest a 2-step model with MUAC used a screening at community level, followed by MUAC and WHZ measured at a primary health care unit, with both indicators used independently to diagnose severe acute malnutrition. Current guidelines should be changed to reflect this, with treatment initiated when either MUAC <115 mm or WHZ<-3.

U2 - 10.1371/journal.pone.0101159

DO - 10.1371/journal.pone.0101159

M3 - Journal article

C2 - 24983995

VL - 9

JO - P L o S One

JF - P L o S One

SN - 1932-6203

IS - 7

M1 - e101159

ER -

ID: 140210128