Newborn regional body composition is influenced by maternal obesity, gestational weight gain and the birthweight standard score

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E M Carlsen, Kristina Martha Renault, K Nørgaard, Lisbeth Nilas, J E B Jensen, L Hyldstrup, Kim F. Michaelsen, Dina Cortes, Ole Pryds

AIM: This study investigated whether newborn body composition is influenced by prepregnancy obesity and gestational weight gain (GWG) and explored any associations between body composition and birthweight standard score (z-score), categorised by size for gestational age.

METHODS: We recruited 231 obese and 80 normal weight mothers and their newborn infants and assessed the babies' body composition using dual-energy X-ray absorptiometry.

RESULTS: The total and abdominal fat masses of infants born to mother who were obese before pregnancy were 135 g (p < 0.001) and 18 g (p < 0.001) higher than the offspring of normal weight mothers. The infants' fat mass increased by 11 g (p < 0.001) for every kilogram of GWG. There were no associations between prepregnancy obesity and fat-free mass. The fat percentage was significantly higher in infants who were large for gestational age (15.3%) than small for gestational age (5.2%) and appropriate for gestational age (9.8%) (p < 0.001). Lower birthweight z-score was associated with a higher proportion of abdominal fat mass (p = 0.009).

CONCLUSION: Infants born to obese mothers had higher fat mass at birth, with abdominal fat accumulation. Low birthweight was associated with a lower crude abdominal fat mass, but a higher proportion of total fat mass placed abdominally.

OriginalsprogEngelsk
TidsskriftActa Paediatrica
Vol/bind103
Udgave nummer9
Sider (fra-til)939-945
Antal sider7
ISSN0803-5253
DOI
StatusUdgivet - 2014

Bibliografisk note

CURIS 2014 NEXS 266

ID: 123729639