Linear growth faltering and the role of weight attainment: Prospective analysis of young children recovering from severe wasting in Niger
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
- Isanaka et al_Maternal & Child Nutrition_2019_Vol 15(4)_e12817
Forlagets udgivne version, 272 KB, PDF-dokument
Sheila Isanaka, Matt D T Hitchings, Fatou Berthé, André Briend, Rebecca F Grais
Efforts to reduce the impact of stunting have been largely independent of interventions to reduce the impact of wasting, despite the observation that the conditions can coexist in the same child and increase risk of death. To optimize the management of malnourished children-who can be wasted, stunted, or both-the relationship between stunting and wasting should be elaborated. We aimed to describe the relationship between concurrent weight and height gain during and after rehabilitation from severe wasting. We conducted a secondary analysis of a randomized trial for the outpatient treatment of severe wasting, including 1,542 children who recovered and were followed for 12 weeks. We described the overlap of stunting and severe wasting and the change in stunting over time. We showed the relationship between concurrent weight and height gain using adjusted generalized estimating equations and calculated the mean rate of change in weight-for-height z score (WHZ) and height-for-age z score (HAZ) during and after rehabilitation. At baseline, 79% (n = 1,223/1,542) and 49% (n = 757/1,542) of children were stunted and severely stunted, respectively. Prevalence increased over time among children <24 months. During rehabilitation when weight was not yet fully recovered, we found rapid WHZ gain but limited HAZ gain. Following successful rehabilitation, WHZ gain slowed. The rate of HAZ gain was negative after rehabilitation but increased relative to the period during treatment. The potential relationship between weight and height gain calls for increased coverage of wasting treatment to not only prevent child mortality but also reduce linear growth faltering.
|Tidsskrift||Maternal and Child Nutrition|
|Status||Udgivet - 2019|
CURIS 2019 NEXS 254
© 2019 The Authors Maternal & Child Nutrition Published by John Wiley & Sons Ltd.
- Det Natur- og Biovidenskabelige Fakultet