Lactobacillus paracasei subsp paracasei L. casei W8 suppresses energy intake acutely

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Lactobacillus paracasei subsp paracasei L. casei W8 suppresses energy intake acutely. / Bjerg, Anne Toksvig; Kristensen, Mette Bredal; Ritz, Christian; Holst, Jens Juul; Rasmussen, Charlotte; Leser, Thomas Dyrmann; Wellejus, Anja; Astrup, Arne.

I: Appetite, Bind 82, 2014, s. 111-118.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Bjerg, AT, Kristensen, MB, Ritz, C, Holst, JJ, Rasmussen, C, Leser, TD, Wellejus, A & Astrup, A 2014, 'Lactobacillus paracasei subsp paracasei L. casei W8 suppresses energy intake acutely', Appetite, bind 82, s. 111-118. https://doi.org/10.1016/j.appet.2014.07.016

APA

Bjerg, A. T., Kristensen, M. B., Ritz, C., Holst, J. J., Rasmussen, C., Leser, T. D., ... Astrup, A. (2014). Lactobacillus paracasei subsp paracasei L. casei W8 suppresses energy intake acutely. Appetite, 82, 111-118. https://doi.org/10.1016/j.appet.2014.07.016

Vancouver

Bjerg AT, Kristensen MB, Ritz C, Holst JJ, Rasmussen C, Leser TD o.a. Lactobacillus paracasei subsp paracasei L. casei W8 suppresses energy intake acutely. Appetite. 2014;82:111-118. https://doi.org/10.1016/j.appet.2014.07.016

Author

Bjerg, Anne Toksvig ; Kristensen, Mette Bredal ; Ritz, Christian ; Holst, Jens Juul ; Rasmussen, Charlotte ; Leser, Thomas Dyrmann ; Wellejus, Anja ; Astrup, Arne. / Lactobacillus paracasei subsp paracasei L. casei W8 suppresses energy intake acutely. I: Appetite. 2014 ; Bind 82. s. 111-118.

Bibtex

@article{0ac1c501eb924d3483179137b0abee7b,
title = "Lactobacillus paracasei subsp paracasei L. casei W8 suppresses energy intake acutely",
abstract = "Background: Probiotic bacteria have been shown to have various effects on the microbiota; this may also affect appetite and may help promote weight loss and maintenance. Objective: This study was conducted to investigate the effect of Lactobacillus paracasei subsp paracasei L. casei W8 (L. casei W8) on glucagon-like peptide-1 (GLP-1) responses in an isolated pig intestine, in piglets and postprandially in humans. Additionally, the effect on subjective appetite, ad libitum energy intake, and glucose and insulin responses in humans was investigated. Design: Piglets were fed with probiotics for 2 weeks and the effect on glucagon encoding gene (GCG) was investigated. An isolated pig intestine was perfused with L. casei W8 and the GLP-1 response was measured. Twenty-one subjects completed a randomized, controlled, crossover study with three arms. Each participant completed 3 test days testing the effect of low dose (LD) (10(9) CFU), high dose (HD) (10(10) CFU) L. casei W8 or placebo capsule. Subjective appetite was assessed before an ad libitum lunch was served. GLP-1, insulin and glucose concentrations were analyzed. Results: Two weeks of treatment of piglets with L. casei W8 resulted in an increase in GCG expression compared to control animals (P <0.05). (p  an and appetite but casei effect effects energy glp-1 glucose had humans, in increased insulin intake intestine. isolated l. no observed on overall pig release response sensation, subjective the w8 were> 0.1). Conclusion: The probiotic bacteria L. casei W8 appears to lower food intake acutely, but the underlying mechanisms are not understood.",
author = "Bjerg, {Anne Toksvig} and Kristensen, {Mette Bredal} and Christian Ritz and Holst, {Jens Juul} and Charlotte Rasmussen and Leser, {Thomas Dyrmann} and Anja Wellejus and Arne Astrup",
note = "CURIS 2014 NEXS 215",
year = "2014",
doi = "10.1016/j.appet.2014.07.016",
language = "English",
volume = "82",
pages = "111--118",
journal = "Appetite",
issn = "0195-6663",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Lactobacillus paracasei subsp paracasei L. casei W8 suppresses energy intake acutely

AU - Bjerg, Anne Toksvig

AU - Kristensen, Mette Bredal

AU - Ritz, Christian

AU - Holst, Jens Juul

AU - Rasmussen, Charlotte

AU - Leser, Thomas Dyrmann

AU - Wellejus, Anja

AU - Astrup, Arne

N1 - CURIS 2014 NEXS 215

PY - 2014

Y1 - 2014

N2 - Background: Probiotic bacteria have been shown to have various effects on the microbiota; this may also affect appetite and may help promote weight loss and maintenance. Objective: This study was conducted to investigate the effect of Lactobacillus paracasei subsp paracasei L. casei W8 (L. casei W8) on glucagon-like peptide-1 (GLP-1) responses in an isolated pig intestine, in piglets and postprandially in humans. Additionally, the effect on subjective appetite, ad libitum energy intake, and glucose and insulin responses in humans was investigated. Design: Piglets were fed with probiotics for 2 weeks and the effect on glucagon encoding gene (GCG) was investigated. An isolated pig intestine was perfused with L. casei W8 and the GLP-1 response was measured. Twenty-one subjects completed a randomized, controlled, crossover study with three arms. Each participant completed 3 test days testing the effect of low dose (LD) (10(9) CFU), high dose (HD) (10(10) CFU) L. casei W8 or placebo capsule. Subjective appetite was assessed before an ad libitum lunch was served. GLP-1, insulin and glucose concentrations were analyzed. Results: Two weeks of treatment of piglets with L. casei W8 resulted in an increase in GCG expression compared to control animals (P <0.05). (p  an and appetite but casei effect effects energy glp-1 glucose had humans, in increased insulin intake intestine. isolated l. no observed on overall pig release response sensation, subjective the w8 were> 0.1). Conclusion: The probiotic bacteria L. casei W8 appears to lower food intake acutely, but the underlying mechanisms are not understood.

AB - Background: Probiotic bacteria have been shown to have various effects on the microbiota; this may also affect appetite and may help promote weight loss and maintenance. Objective: This study was conducted to investigate the effect of Lactobacillus paracasei subsp paracasei L. casei W8 (L. casei W8) on glucagon-like peptide-1 (GLP-1) responses in an isolated pig intestine, in piglets and postprandially in humans. Additionally, the effect on subjective appetite, ad libitum energy intake, and glucose and insulin responses in humans was investigated. Design: Piglets were fed with probiotics for 2 weeks and the effect on glucagon encoding gene (GCG) was investigated. An isolated pig intestine was perfused with L. casei W8 and the GLP-1 response was measured. Twenty-one subjects completed a randomized, controlled, crossover study with three arms. Each participant completed 3 test days testing the effect of low dose (LD) (10(9) CFU), high dose (HD) (10(10) CFU) L. casei W8 or placebo capsule. Subjective appetite was assessed before an ad libitum lunch was served. GLP-1, insulin and glucose concentrations were analyzed. Results: Two weeks of treatment of piglets with L. casei W8 resulted in an increase in GCG expression compared to control animals (P <0.05). (p  an and appetite but casei effect effects energy glp-1 glucose had humans, in increased insulin intake intestine. isolated l. no observed on overall pig release response sensation, subjective the w8 were> 0.1). Conclusion: The probiotic bacteria L. casei W8 appears to lower food intake acutely, but the underlying mechanisms are not understood.

U2 - 10.1016/j.appet.2014.07.016

DO - 10.1016/j.appet.2014.07.016

M3 - Journal article

C2 - 25049132

VL - 82

SP - 111

EP - 118

JO - Appetite

JF - Appetite

SN - 0195-6663

ER -

ID: 120022082