Determinants of neurodevelopment in early childhood - results from the Copenhagen Prospective Studies on Asthma in Childhood (COPSAC2010 ) Mother-Child Cohort

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Standard

Determinants of neurodevelopment in early childhood - results from the Copenhagen Prospective Studies on Asthma in Childhood (COPSAC2010 ) Mother-Child Cohort. / Bjarnadóttir, Elín; Stokholm, Jakob; Chawes, Bo; Thorsen, Jonathan; Mora-Jensen, Anna Rosa Cecilie; Deleuran, Maja; Bønnelykke, Klaus; Lauritzen, Lotte; Bisgaard, Hans.

I: Acta Paediatrica, 22.03.2019.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Bjarnadóttir, E, Stokholm, J, Chawes, B, Thorsen, J, Mora-Jensen, ARC, Deleuran, M, Bønnelykke, K, Lauritzen, L & Bisgaard, H 2019, 'Determinants of neurodevelopment in early childhood - results from the Copenhagen Prospective Studies on Asthma in Childhood (COPSAC2010 ) Mother-Child Cohort' Acta Paediatrica. https://doi.org/10.1111/apa.14753

APA

Bjarnadóttir, E., Stokholm, J., Chawes, B., Thorsen, J., Mora-Jensen, A. R. C., Deleuran, M., ... Bisgaard, H. (2019). Determinants of neurodevelopment in early childhood - results from the Copenhagen Prospective Studies on Asthma in Childhood (COPSAC2010 ) Mother-Child Cohort. Acta Paediatrica. https://doi.org/10.1111/apa.14753

Vancouver

Bjarnadóttir E, Stokholm J, Chawes B, Thorsen J, Mora-Jensen ARC, Deleuran M o.a. Determinants of neurodevelopment in early childhood - results from the Copenhagen Prospective Studies on Asthma in Childhood (COPSAC2010 ) Mother-Child Cohort. Acta Paediatrica. 2019 mar 22. https://doi.org/10.1111/apa.14753

Author

Bjarnadóttir, Elín ; Stokholm, Jakob ; Chawes, Bo ; Thorsen, Jonathan ; Mora-Jensen, Anna Rosa Cecilie ; Deleuran, Maja ; Bønnelykke, Klaus ; Lauritzen, Lotte ; Bisgaard, Hans. / Determinants of neurodevelopment in early childhood - results from the Copenhagen Prospective Studies on Asthma in Childhood (COPSAC2010 ) Mother-Child Cohort. I: Acta Paediatrica. 2019.

Bibtex

@article{1f40b83fd4e74249915485d3737d7f49,
title = "Determinants of neurodevelopment in early childhood - results from the Copenhagen Prospective Studies on Asthma in Childhood (COPSAC2010 ) Mother-Child Cohort",
abstract = "Aim: The objective of this study was to identify possible pre- and postnatal factors influencing neurodevelopment of the young child.Methods: We used data from the Copenhagen Prospective Studies on Asthma in Childhood 2010 (COPSAC2010) mother-child cohort, but excluded those with a neurological diagnosis, born <37 weeks of gestation and birth weights <2500g, resulting in 650 children analyzed. Neurodevelopment was assessed as age of achievement of early milestones, language scores at 1 and 2 years and cognitive score at 2 ½ years of age.Results: Neurodevelopmental scores were not associated with breastfeeding, persistent wheeze, eczema, and number of sick days (p>0.05 in all tests). Early age at milestone achievement was associated with male sex (p=0.05), lower maternal age (p=0.02), higher gestational age (p<0.001) and paternity leave (p=0.01). A higher 1-year language score was associated with female sex (p=0.02) and maternal smoking during pregnancy (p=0.01) and a higher 2-year language score with female sex (p<0.001) and being first born (p=0.01). A higher cognitive score was associated with female sex (p=0.02).Conclusion: Neurodevelopmental scores were unrelated to breast-feeding, persistent wheeze, eczema, and number of sick days.",
keywords = "The Faculty of Science, Cognitive development, Language development, Motor development, Neurological development",
author = "El{\'i}n Bjarnad{\'o}ttir and Jakob Stokholm and Bo Chawes and Jonathan Thorsen and Mora-Jensen, {Anna Rosa Cecilie} and Maja Deleuran and Klaus B{\o}nnelykke and Lotte Lauritzen and Hans Bisgaard",
note = "CURIS 2019 NEXS 106 This article is protected by copyright. All rights reserved.",
year = "2019",
month = "3",
day = "22",
doi = "10.1111/apa.14753",
language = "English",
journal = "Acta Paediatrica",
issn = "0803-5253",
publisher = "Wiley-Blackwell",

}

RIS

TY - JOUR

T1 - Determinants of neurodevelopment in early childhood - results from the Copenhagen Prospective Studies on Asthma in Childhood (COPSAC2010 ) Mother-Child Cohort

AU - Bjarnadóttir, Elín

AU - Stokholm, Jakob

AU - Chawes, Bo

AU - Thorsen, Jonathan

AU - Mora-Jensen, Anna Rosa Cecilie

AU - Deleuran, Maja

AU - Bønnelykke, Klaus

AU - Lauritzen, Lotte

AU - Bisgaard, Hans

N1 - CURIS 2019 NEXS 106 This article is protected by copyright. All rights reserved.

PY - 2019/3/22

Y1 - 2019/3/22

N2 - Aim: The objective of this study was to identify possible pre- and postnatal factors influencing neurodevelopment of the young child.Methods: We used data from the Copenhagen Prospective Studies on Asthma in Childhood 2010 (COPSAC2010) mother-child cohort, but excluded those with a neurological diagnosis, born <37 weeks of gestation and birth weights <2500g, resulting in 650 children analyzed. Neurodevelopment was assessed as age of achievement of early milestones, language scores at 1 and 2 years and cognitive score at 2 ½ years of age.Results: Neurodevelopmental scores were not associated with breastfeeding, persistent wheeze, eczema, and number of sick days (p>0.05 in all tests). Early age at milestone achievement was associated with male sex (p=0.05), lower maternal age (p=0.02), higher gestational age (p<0.001) and paternity leave (p=0.01). A higher 1-year language score was associated with female sex (p=0.02) and maternal smoking during pregnancy (p=0.01) and a higher 2-year language score with female sex (p<0.001) and being first born (p=0.01). A higher cognitive score was associated with female sex (p=0.02).Conclusion: Neurodevelopmental scores were unrelated to breast-feeding, persistent wheeze, eczema, and number of sick days.

AB - Aim: The objective of this study was to identify possible pre- and postnatal factors influencing neurodevelopment of the young child.Methods: We used data from the Copenhagen Prospective Studies on Asthma in Childhood 2010 (COPSAC2010) mother-child cohort, but excluded those with a neurological diagnosis, born <37 weeks of gestation and birth weights <2500g, resulting in 650 children analyzed. Neurodevelopment was assessed as age of achievement of early milestones, language scores at 1 and 2 years and cognitive score at 2 ½ years of age.Results: Neurodevelopmental scores were not associated with breastfeeding, persistent wheeze, eczema, and number of sick days (p>0.05 in all tests). Early age at milestone achievement was associated with male sex (p=0.05), lower maternal age (p=0.02), higher gestational age (p<0.001) and paternity leave (p=0.01). A higher 1-year language score was associated with female sex (p=0.02) and maternal smoking during pregnancy (p=0.01) and a higher 2-year language score with female sex (p<0.001) and being first born (p=0.01). A higher cognitive score was associated with female sex (p=0.02).Conclusion: Neurodevelopmental scores were unrelated to breast-feeding, persistent wheeze, eczema, and number of sick days.

KW - The Faculty of Science

KW - Cognitive development

KW - Language development

KW - Motor development

KW - Neurological development

U2 - 10.1111/apa.14753

DO - 10.1111/apa.14753

M3 - Journal article

JO - Acta Paediatrica

JF - Acta Paediatrica

SN - 0803-5253

ER -

ID: 213319895