BCG protects against tuberculosis irrespective of HIV status: a matched case-control study in Mwanza, Tanzania

Publikation: Bidrag til tidsskriftLetterForskningfagfællebedømt

Daniel Faurholt-Jepsen, Nyagosya Range, George PrayGod, Kidola Jeremiah, Maria Faurholt-Jepsen, Martine G Aabye, Harleen M S Grewal, John Changalucha, Daniel R Witte, Aase B Andersen, Henrik Friis

While BCG vaccine protects against severe tuberculosis (TB) in children, its effect against adult TB is questionable. Furthermore, it is not known if HIV co-infection modifies the effect of BCG. Among 352 pairs of Tanzanian TB cases and matched controls, the BCG scar was associated with a reduced risk of TB (OR 0.3, 95% CI 0.2 to 0.7, p=0.005), irrespective of HIV status (interaction, p=0.623). BCG vaccination considerably reduced the risk of TB, both among individuals with and without HIV infection.
OriginalsprogEngelsk
TidsskriftThorax
Vol/bind68
Udgave nummer3
Sider (fra-til)288-289
Antal sider2
ISSN0040-6376
DOI
StatusUdgivet - 2013

Bibliografisk note

CURIS 2013 NEXS 044

ID: 44566701