Added value of IP-10 as a read-out of Mycobacterium tuberculosis: Specific immunity in young children

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Synne Jenum, Sivmakumaran Dhanasekaran, Christian Ritz, Ragini Macaden, T Mark Doherty, Harleen M.S. Grewal, TB Trials Study Group

We have explored the added value of IFNγ-inducible protein 10 as a read-out of Mycobacterium tuberculosis specific immunity in young Indian children where the sensitivity of the IGRA for tuberculosis (TB) is poor. Reduced frequency of indeterminate results and an increased sensitivity for TB, suggest a potential for fewer missed cases with a combined IFNγ/IP-10 read-out in a 4 generation IGRA.This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially.

OriginalsprogEngelsk
TidsskriftPediatric Infectious Disease Journal
Vol/bind35
Udgave nummer12
Sider (fra-til)1336-1338
Antal sider3
ISSN0891-3668
DOI
StatusUdgivet - 2016

Bibliografisk note

CURIS 2016 NEXS 329

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