Regulation of skeletal muscle glycogenolysis during exercise

Research output: Contribution to journal › Review › Research › peer-review

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Regulation of skeletal muscle glycogenolysis during exercise. / Hargreaves, M; Richter, Erik A.

In: Canadian Journal of Sport Sciences, Vol. 13, No. 4, 1988, p. 197-203.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Hargreaves, M & Richter, EA 1988, 'Regulation of skeletal muscle glycogenolysis during exercise', Canadian Journal of Sport Sciences, vol. 13, no. 4, pp. 197-203.

APA

Hargreaves, M., & Richter, E. A. (1988). Regulation of skeletal muscle glycogenolysis during exercise. Canadian Journal of Sport Sciences, 13(4), 197-203.

Vancouver

Hargreaves M, Richter EA. Regulation of skeletal muscle glycogenolysis during exercise. Canadian Journal of Sport Sciences. 1988;13(4):197-203.

Author

Hargreaves, M ; Richter, Erik A. / Regulation of skeletal muscle glycogenolysis during exercise. In: Canadian Journal of Sport Sciences. 1988 ; Vol. 13, No. 4. pp. 197-203.

Bibtex

@article{ca3085d37fef41ccbfd831cf23130001,
title = "Regulation of skeletal muscle glycogenolysis during exercise",
abstract = "Muscle-glycogen breakdown during exercise is influenced by both local and systemic factors. Contractions per se increase glycogenolysis via a calcium-induced, transient increase in the activity of phosphorylase a, and probably also via increased concentrations of Pi. In fast-twitch muscle, increases in the AMP and IMP levels may increase phosphorylase activity. The rate of muscle-glycogen breakdown during exercise depends on the pre-exercise glycogen concentration and is also influenced by hormones. Insulin may inhibit glycogen breakdown, whereas epinephrine enhances the rate of glycogen use in contracting muscle by increasing the phosphorylase a activity via increased cyclic AMP production. The availability of blood-borne substrates may also influence muscle glycogenolysis and, therefore, exercise performance.",
keywords = "Blood Glucose, Calcium, Epinephrine, Exercise, Glycogen, Humans, Insulin, Muscles, Phosphorylases",
author = "M Hargreaves and Richter, {Erik A.}",
year = "1988",
language = "English",
volume = "13",
pages = "197--203",
journal = "Canadian Journal of Sport Sciences",
number = "4",

}

RIS

TY - JOUR

T1 - Regulation of skeletal muscle glycogenolysis during exercise

AU - Hargreaves, M

AU - Richter, Erik A.

PY - 1988

Y1 - 1988

N2 - Muscle-glycogen breakdown during exercise is influenced by both local and systemic factors. Contractions per se increase glycogenolysis via a calcium-induced, transient increase in the activity of phosphorylase a, and probably also via increased concentrations of Pi. In fast-twitch muscle, increases in the AMP and IMP levels may increase phosphorylase activity. The rate of muscle-glycogen breakdown during exercise depends on the pre-exercise glycogen concentration and is also influenced by hormones. Insulin may inhibit glycogen breakdown, whereas epinephrine enhances the rate of glycogen use in contracting muscle by increasing the phosphorylase a activity via increased cyclic AMP production. The availability of blood-borne substrates may also influence muscle glycogenolysis and, therefore, exercise performance.

AB - Muscle-glycogen breakdown during exercise is influenced by both local and systemic factors. Contractions per se increase glycogenolysis via a calcium-induced, transient increase in the activity of phosphorylase a, and probably also via increased concentrations of Pi. In fast-twitch muscle, increases in the AMP and IMP levels may increase phosphorylase activity. The rate of muscle-glycogen breakdown during exercise depends on the pre-exercise glycogen concentration and is also influenced by hormones. Insulin may inhibit glycogen breakdown, whereas epinephrine enhances the rate of glycogen use in contracting muscle by increasing the phosphorylase a activity via increased cyclic AMP production. The availability of blood-borne substrates may also influence muscle glycogenolysis and, therefore, exercise performance.

KW - Blood Glucose

KW - Calcium

KW - Epinephrine

KW - Exercise

KW - Glycogen

KW - Humans

KW - Insulin

KW - Muscles

KW - Phosphorylases

M3 - Review

C2 - 3064902

VL - 13

SP - 197

EP - 203

JO - Canadian Journal of Sport Sciences

JF - Canadian Journal of Sport Sciences

IS - 4

ER -

ID: 154757294