Glucagon regulation of energy expenditure

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Glucagon’s ability to increase energy expenditure has been known for more than 60 years, yet the mechanisms underlining glucagon’s thermogenic effect still remain largely elusive. Over the last years, significant efforts were directed to unravel the physiological and cellular underpinnings of how glucagon regulates energy expenditure. In this review, we summarize the current knowledge on how glucagon regulates systems metabolism with a special emphasis on its acute and chronic thermogenic effects.

Original languageEnglish
Article number5407
JournalInternational Journal of Molecular Sciences
Volume20
Issue number21
Number of pages12
ISSN1661-6596
DOIs
Publication statusPublished - 2019

    Research areas

  • Brown adipose tissue, Energy expenditure, FGF21, Glucagon, Obesity, Pharmacology

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