A scheme for a flexible classification of dietary and health biomarkers
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A scheme for a flexible classification of dietary and health biomarkers. / Gao, Qian; Pratico, Giulia; Scalbert, Augustin; Vergeres, Guy; Kolehmainen, Marjukka; Manach, Claudine; Brennan, Lorraine; Afman, Lydia A; Wishart, David S; Andres-Lacueva, Cristina; Garcia-Aloy, Mar; Verhagen, Hans; Feskens, Edith F M; Dragsted, Lars Ove.
In: Genes & Nutrition, Vol. 12, 34, 2017.Research output: Contribution to journal › Review › Research › peer-review
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TY - JOUR
T1 - A scheme for a flexible classification of dietary and health biomarkers
AU - Gao, Qian
AU - Pratico, Giulia
AU - Scalbert, Augustin
AU - Vergeres, Guy
AU - Kolehmainen, Marjukka
AU - Manach, Claudine
AU - Brennan, Lorraine
AU - Afman, Lydia A
AU - Wishart, David S
AU - Andres-Lacueva, Cristina
AU - Garcia-Aloy, Mar
AU - Verhagen, Hans
AU - Feskens, Edith F M
AU - Dragsted, Lars Ove
N1 - CURIS 2017 NEXS 347
PY - 2017
Y1 - 2017
N2 - Biomarkers are an efficient means to examine intakes or exposures and their biological effects and to assess system susceptibility. Aided by novel profiling technologies, the biomarker research field is undergoing rapid developmentand new putative biomarkers are continuously emerging in the scientific literature. However, the existing concepts for classification of biomarkers in the dietary and health area may be ambiguous, leading to uncertainty about theirapplication. In order to better understand the potential of biomarkers and to communicate their use and application, it is imperative to have a solid scheme for biomarker classification that will provide a well-defined ontology for thefield. In this manuscript, we provide an improved scheme for biomarker classification based on their intended use rather than the technology or outcomes (six subclasses are suggested: food compound intake biomarkers (FCIBs), food or food component intake biomarkers (FIBs), dietary pattern biomarkers (DPBs), food compound status biomarkers (FCSBs), effect biomarkers, physiological or health state biomarkers). The application of this scheme is described in detail for the dietary and health area and is compared with previous biomarker classification for this field of research.
AB - Biomarkers are an efficient means to examine intakes or exposures and their biological effects and to assess system susceptibility. Aided by novel profiling technologies, the biomarker research field is undergoing rapid developmentand new putative biomarkers are continuously emerging in the scientific literature. However, the existing concepts for classification of biomarkers in the dietary and health area may be ambiguous, leading to uncertainty about theirapplication. In order to better understand the potential of biomarkers and to communicate their use and application, it is imperative to have a solid scheme for biomarker classification that will provide a well-defined ontology for thefield. In this manuscript, we provide an improved scheme for biomarker classification based on their intended use rather than the technology or outcomes (six subclasses are suggested: food compound intake biomarkers (FCIBs), food or food component intake biomarkers (FIBs), dietary pattern biomarkers (DPBs), food compound status biomarkers (FCSBs), effect biomarkers, physiological or health state biomarkers). The application of this scheme is described in detail for the dietary and health area and is compared with previous biomarker classification for this field of research.
KW - Faculty of Science
KW - Biomarker
KW - Classification
KW - Nutrition
KW - Ontology
KW - Exposure
KW - Effect
KW - Susceptibility
KW - Metabolomics
KW - Review
U2 - 10.1186/s12263-017-0587-x
DO - 10.1186/s12263-017-0587-x
M3 - Review
C2 - 29255495
VL - 12
JO - Genes & Nutrition
JF - Genes & Nutrition
SN - 1555-8932
M1 - 34
ER -
ID: 186705601