Maximilian Kleinert

Maximilian Kleinert

Assistant Professor


  1. 2023
  2. Published

    Cross-species comparison of pregnancy-induced GDF15

    Klein, A. B., Ranea-Robles, Pablo, Nicolaisen, T. S., Gil, Cláudia, Johann, K., Prats Quesada, Júlia, Pistoljevic, N., Hviid, K. V. R., Olsen, L. F., Offersen, Simone Margaard, Helge, Jørn Wulff, Nielsen, Henriette Svarre, Bakker, J., Kleinert, Maximilian & Clemmensen, Christoffer, 2023, In: American Journal of Physiology - Endocrinology and Metabolism. 325, 4, p. E303-E309

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Dietary medium-chain fatty acids reduce food intake via the GDF15-GFRAL axis in mice

    Kanta, Josephine Maria, Deisen, L., Johann, K., Holm, Stephanie Kjærulff, Lundsgaard, Anne-Marie, Lund, Jens, Jähnert, M., Schürmann, A., Clemmensen, Christoffer, Kiens, Bente, Fritzen, Andreas Mæchel & Kleinert, Maximilian, 2023, In: Molecular Metabolism. 74, 10 p., 101760.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Neuronal loss of TRPM8 leads to obesity and glucose intolerance in male mice

    Liskiewicz, D., Zhang, Q., Barthem, C. S., Jastroch, M., Liskiewicz, A., Khajavi, N., Grandl, G., Coupland, C., Kleinert, Maximilian, Garcia-Caceres, C., Novikoff, A., Maity, G., Boehm, U., Tschöp, M. H. & Müller, T. D., 2023, In: Molecular Metabolism. 72, 10 p., 101714.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Skeletal muscle and intermuscular adipose tissue gene expression profiling identifies new biomarkers with prognostic significance for insulin resistance progression and intervention response

    Lutter, D., Sachs, S., Walter, M., Kerege, A., Perreault, L., Kahn, D. E., Wolide, A. D., Kleinert, Maximilian, Bergman, B. C. & Hofmann, S. M., 2023, In: Diabetologia. 66, 5, p. 873-883 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    The anorectic and thermogenic effects of pharmacological lactate in male mice are confounded by treatment osmolarity and co-administered counterions

    Lund, J., Breum, A. W., Gil, C., Falk, S., Sass, F., Isidor, M. S., Dmytriyeva, O., Ranea-Robles, P., Mathiesen, C. V., Basse, A. L., Johansen, O. S., Fadahunsi, N., Lund, C., Nicolaisen, T. S., Klein, A. B., Ma, T., Emanuelli, B., Kleinert, M., Sørensen, C. M., Gerhart-Hines, Z. & 1 others, Clemmensen, Christoffer, 2023, In: Nature Metabolism. 5, 4, p. 677-698 22 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2022
  8. Published

    In vivo metabolic effects after acute activation of skeletal muscle Gs signaling

    Meister, J., Bone, D. B. J., Knudsen, Jonas Roland, Barella, L. F., Liu, L., Lee, R., Gavrilova, O., Chen, M., Weinstein, L. S., Kleinert, Maximilian, Jensen, Thomas Elbenhardt & Wess, J., 2022, In: Molecular Metabolism. 55, 9 p., 101415.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Clenbuterol exerts antidiabetic activity through metabolic reprogramming of skeletal muscle cells

    Meister, J., Bone, D. B. J., Knudsen, Jonas Roland, Barella, L. F., Velenosi, T. J., Akhmedov, D., Lee, R. J., Cohen, A. H., Gavrilova, O., Cui, Y., Karsenty, G., Chen, M., Weinstein, L. S., Kleinert, Maximilian, Berdeaux, R., Jensen, Thomas Elbenhardt, Richter, Erik A. & Wess, J., 2022, In: Nature Communications. 13, 14 p., 22.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Exercise increases phosphorylation of the putative mTORC2 activity readout NDRG1 in human skeletal muscle

    Knudsen, Jonas Roland, Persson, Kaspar Wredstrøm, Meister, J., Carl, Christian Strini, Raun, Steffen Henning, Andersen, Nicoline Resen, Sylow, Lykke, Kiens, Bente, Jensen, Thomas Elbenhardt, Richter, Erik A. & Kleinert, Maximilian, 2022, In: American Journal of Physiology: Endocrinology and Metabolism. 322, 1, p. E63-E73 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    GDF15 in appetite and exercise: Essential player or coincidental bystander?

    Klein, A. B., Kleinert, Maximilian, Richter, Erik A. & Clemmensen, Christoffer, 2022, In: Endocrinology. 163, 1, p. 1-10 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  12. Published

    Genes controlling skeletal muscle glucose uptake and their regulation by endurance and resistance exercise

    Verbrugge, S. A. J., Alhusen, J. A., Kempin, S., Pillon, N. J., Rozman, J., Wackerhage, H. & Kleinert, Maximilian, 2022, In: Journal of Cellular Biochemistry. 123, 2, p. 202-214 13 p.

    Research output: Contribution to journalReviewResearchpeer-review

  13. Published

    The GDF15-GFRAL pathway is dispensable for the effects of metformin on energy balance

    Klein, A. B., Nicolaisen, T. S., Johann, K., Fritzen, Andreas Mæchel, Mathiesen, C. V., Gil, Cláudia, Pilmark, N. S., Karstoft, Kristian, Blond, Martin Bæk, Quist, Jonas Salling, Seeley, R. J., Færch, K., Lund, Jens, Kleinert, Maximilian & Clemmensen, Christoffer, 2022, In: Cell Reports. 40, 8, 111258.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    The effect of dextrose or protein ingestion on circulating growth differentiation factor 15 and appetite in older compared to younger women

    Herpich, C., Lehmann, S., Kochlik, B., Kleinert, Maximilian, Klaus, S., Müller-Werdan, U. & Norman, K., 2022, In: Nutrients. 14, 19, 9 p., 4066.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2021
  16. Published

    Glucagon's metabolic action in health and disease

    Zeigerer, A., Sekar, R., Kleinert, Maximilian, Nason, S., Habegger, K. M. & Müller, T. D., 2021, In: Comprehensive Physiology. 11, 2, p. 1759-1783 25 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Pharmacological but not physiological GDF15 suppresses feeding and the motivation to exercise

    Klein, A. B., Nicolaisen, T. S., Ørtenblad, N., Gejl, K. D., Jensen, R., Fritzen, A. M., Larsen, E. L., Karstoft, K., Poulsen, H. E., Morville, T., Sahl, R. E., Helge, J. W., Lund, J., Falk, S., Lyngbæk, M., Ellingsgaard, H., Pedersen, B. K., Lu, W., Finan, B., Jørgensen, S. B. & 5 others, Seeley, R. J., Kleinert, Maximilian, Kiens, Bente, Richter, Erik A. & Clemmensen, Christoffer, 2021, In: Nature Communications. 12, 9 p., 1041.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Small amounts of dietary medium-chain fatty acids protect against insulin resistance during caloric excess in humans

    Lundsgaard, Anne-Marie, Fritzen, Andreas Mæchel, Sjøberg, K. A., Kleinert, Maximilian, Richter, Erik A. & Kiens, Bente, 2021, In: Diabetes. 70, 1, p. 91-98 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Spatiotemporal GLP-1 and GIP receptor signaling and trafficking/recycling dynamics induced by selected receptor mono- and dual-agonists

    Novikoff, A., O'Brien, S. L., Bernecker, M., Grandl, G., Kleinert, Maximilian, Knerr, P. J., Stemmer, K., Klingenspor, M., Zeigerer, A., DiMarchi, R., Tschöp, M. H., Finan, B., Calebiro, D. & Müller, T. D., 2021, In: Molecular Metabolism. 49, 11 p., 101181.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. The glucose-dependent insulinotropic polypeptide (GIP) regulates body weight and food intake via CNS-GIPR signaling

    Zhang, Q., Delessa, C. T., Augustin, R., Bakhti, M., Colldén, G., Drucker, D. J., Feuchtinger, A., Caceres, C. G., Grandl, G., Harger, A., Herzig, S., Hofmann, S., Holleman, C. L., Jastroch, M., Keipert, S., Kleinert, M., Knerr, P. J., Kulaj, K., Legutko, B., Lickert, H. & 16 others, Liu, X., Luippold, G., Lutter, D., Malogajski, E., Medina, M. T., Mowery, S. A., Blutke, A., Perez-Tilve, D., Salinno, C., Sehrer, L., DiMarchi, R. D., Tschöp, M. H., Stemmer, K., Finan, B., Wolfrum, C. & Müller, T. D., 2021, In: Cell Metabolism. 33, 4, p. 833-844.e5 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    The role of GDF15 as a myomitokine

    Johann, K., Kleinert, Maximilian & Klaus, S., 2021, In: Cells. 10, 11, 16 p., 2990.

    Research output: Contribution to journalReviewResearchpeer-review

  22. 2020
  23. Published

    A new FGF21 analog for the treatment of fatty liver disease

    Kleinert, Maximilian & Müller, T. D., 2020, In: Diabetes. 69, 8, p. 1605-1607 3 p.

    Research output: Contribution to journalComment/debateResearch

  24. Published

    ApoA-1 improves glucose tolerance by increasing glucose uptake into heart and skeletal muscle independently of AMPKα2

    Fritzen, Andreas Mæchel, Domingo-Espín, J., Lundsgaard, Anne-Marie, Kleinert, Maximilian, Israelsen, I., Carl, Christian Strini, Nicolaisen, T. S., Kjøbsted, Rasmus, Jeppesen, J. F., Wojtaszewski, Jørgen F P, Lagerstedt, J. O. & Kiens, Bente, 2020, In: Molecular Metabolism. 35, 11 p., 100949.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Glucometabolic consequences of acute and prolonged inhibition of fatty acid oxidation

    Lundsgaard, Anne-Marie, Fritzen, Andreas Mæchel, Nicolaisen, T. S., Carl, Christian Strini, Sjøberg, K. A., Raun, Steffen Henning, Klein, A. B., Sanchez-Quant, E., Langer, J., Ørskov, Cathrine, Clemmensen, Christoffer, Tschöp, M. H., Richter, Erik A., Kiens, Bente & Kleinert, Maximilian, 2020, In: Journal of Lipid Research. 61, 1, p. 10-19 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Growth factor-dependent and -independent activation of mTORC2

    Knudsen, Jonas Roland, Fritzen, Andreas Mæchel, James, D. E., Jensen, Thomas Elbenhardt, Kleinert, Maximilian & Richter, Erik A., 2020, In: Trends in Endocrinology and Metabolism. 31, 1, p. 13-24 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  27. Published

    Pharmacological targeting of α3β4 nicotinic receptors improves peripheral insulin sensitivity in mice with diet-induced obesity

    Jall, S., De Angelis, M., Lundsgaard, Anne-Marie, Fritzen, Andreas Mæchel, Nicolaisen, T. S., Klein, A. B., Novikoff, A., Sachs, S., Richter, Erik A., Kiens, Bente, Schramm, K., Tschöp, M. H., Stemmer, K., Clemmensen, Christoffer, Müller, T. D. & Kleinert, Maximilian, 2020, In: Diabetologia. 63, 6, p. 1236-1247 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Plasma proteome profiles treatment efficacy of incretin dual agonism in diet-induced obese female and male mice

    Sachs, S., Niu, Lili, Geyer, P., Jall, S., Kleinert, Maximilian, Feuchtinger, A., Stemmer, K., Brielmeier, M., Finan, B., DiMarchi, R. D., Tschop, M. H., Albrechtsen, Nicolai Jacob Wewer, Mann, Matthias, Mueller, T. D. & Hofmann, S. M., 2020, In: Diabetes, Obesity and Metabolism. 23, 1, p. 195-207 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Targeted pharmacological therapy restores β-cell function for diabetes remission

    Sachs, S., Bastidas-Ponce, A., Tritschler, S., Bakhti, M., Böttcher, A., Sánchez-Garrido, M. A., Tarquis-Medina, M., Kleinert, M., Fischer, K., Jall, S., Harger, A., Bader, E., Roscioni, S., Ussar, S., Feuchtinger, A., Yesildag, B., Neelakandhan, A., Jensen, C. B., Cornu, M., Yang, B. & 7 others, Finan, B., DiMarchi, R. D., Tschöp, M. H., Theis, F. J., Hofmann, S. M., Müller, T. D. & Lickert, H., 2020, In: Nature Metabolism. 2, 2, p. 192-209 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 23329589