Maximilian Kleinert
Assistant Professor
The August Krogh Section for Molecular Physiology
Nørre Allé 51
2200 København N
- 2023
- Published
Cross-species comparison of pregnancy-induced GDF15
Klein, A. B., Ranea-Robles, Pablo, Nicolaisen, T. S., Gil, Cláudia, Johann, K., Prats Quesada, Júlia, Pistoljevic, N., Hviid, K. V. R., Olsen, L. F., Offersen, Simone Margaard, Helge, Jørn Wulff, Nielsen, Henriette Svarre, Bakker, J., Kleinert, Maximilian & Clemmensen, Christoffer, 2023, In: American Journal of Physiology - Endocrinology and Metabolism. 325, 4, p. E303-E309Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dietary medium-chain fatty acids reduce food intake via the GDF15-GFRAL axis in mice
Kanta, Josephine Maria, Deisen, L., Johann, K., Holm, Stephanie Kjærulff, Lundsgaard, Anne-Marie, Lund, Jens, Jähnert, M., Schürmann, A., Clemmensen, Christoffer, Kiens, Bente, Fritzen, Andreas Mæchel & Kleinert, Maximilian, 2023, In: Molecular Metabolism. 74, 10 p., 101760.Research output: Contribution to journal › Journal article › Research › peer-review
Neuronal loss of TRPM8 leads to obesity and glucose intolerance in male mice
Liskiewicz, D., Zhang, Q., Barthem, C. S., Jastroch, M., Liskiewicz, A., Khajavi, N., Grandl, G., Coupland, C., Kleinert, Maximilian, Garcia-Caceres, C., Novikoff, A., Maity, G., Boehm, U., Tschöp, M. H. & Müller, T. D., 2023, In: Molecular Metabolism. 72, 10 p., 101714.Research output: Contribution to journal › Journal article › Research › peer-review
Skeletal muscle and intermuscular adipose tissue gene expression profiling identifies new biomarkers with prognostic significance for insulin resistance progression and intervention response
Lutter, D., Sachs, S., Walter, M., Kerege, A., Perreault, L., Kahn, D. E., Wolide, A. D., Kleinert, Maximilian, Bergman, B. C. & Hofmann, S. M., 2023, In: Diabetologia. 66, 5, p. 873-883 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The anorectic and thermogenic effects of pharmacological lactate in male mice are confounded by treatment osmolarity and co-administered counterions
Lund, J., Breum, A. W., Gil, C., Falk, S., Sass, F., Isidor, M. S., Dmytriyeva, O., Ranea-Robles, P., Mathiesen, C. V., Basse, A. L., Johansen, O. S., Fadahunsi, N., Lund, C., Nicolaisen, T. S., Klein, A. B., Ma, T., Emanuelli, B., Kleinert, M., Sørensen, C. M., Gerhart-Hines, Z. & 1 others, , 2023, In: Nature Metabolism. 5, 4, p. 677-698 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
In vivo metabolic effects after acute activation of skeletal muscle Gs signaling
Meister, J., Bone, D. B. J., Knudsen, Jonas Roland, Barella, L. F., Liu, L., Lee, R., Gavrilova, O., Chen, M., Weinstein, L. S., Kleinert, Maximilian, Jensen, Thomas Elbenhardt & Wess, J., 2022, In: Molecular Metabolism. 55, 9 p., 101415.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clenbuterol exerts antidiabetic activity through metabolic reprogramming of skeletal muscle cells
Meister, J., Bone, D. B. J., Knudsen, Jonas Roland, Barella, L. F., Velenosi, T. J., Akhmedov, D., Lee, R. J., Cohen, A. H., Gavrilova, O., Cui, Y., Karsenty, G., Chen, M., Weinstein, L. S., Kleinert, Maximilian, Berdeaux, R., Jensen, Thomas Elbenhardt, Richter, Erik A. & Wess, J., 2022, In: Nature Communications. 13, 14 p., 22.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exercise increases phosphorylation of the putative mTORC2 activity readout NDRG1 in human skeletal muscle
Knudsen, Jonas Roland, Persson, Kaspar Wredstrøm, Meister, J., Carl, Christian Strini, Raun, Steffen Henning, Andersen, Nicoline Resen, Sylow, Lykke, Kiens, Bente, Jensen, Thomas Elbenhardt, Richter, Erik A. & Kleinert, Maximilian, 2022, In: American Journal of Physiology: Endocrinology and Metabolism. 322, 1, p. E63-E73 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GDF15 in appetite and exercise: Essential player or coincidental bystander?
Klein, A. B., Kleinert, Maximilian, Richter, Erik A. & Clemmensen, Christoffer, 2022, In: Endocrinology. 163, 1, p. 1-10 10 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Genes controlling skeletal muscle glucose uptake and their regulation by endurance and resistance exercise
Verbrugge, S. A. J., Alhusen, J. A., Kempin, S., Pillon, N. J., Rozman, J., Wackerhage, H. & Kleinert, Maximilian, 2022, In: Journal of Cellular Biochemistry. 123, 2, p. 202-214 13 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The GDF15-GFRAL pathway is dispensable for the effects of metformin on energy balance
Klein, A. B., Nicolaisen, T. S., Johann, K., Fritzen, Andreas Mæchel, Mathiesen, C. V., Gil, Cláudia, Pilmark, N. S., Karstoft, Kristian, Blond, Martin Bæk, Quist, Jonas Salling, Seeley, R. J., Færch, K., Lund, Jens, Kleinert, Maximilian & Clemmensen, Christoffer, 2022, In: Cell Reports. 40, 8, 111258.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of dextrose or protein ingestion on circulating growth differentiation factor 15 and appetite in older compared to younger women
Herpich, C., Lehmann, S., Kochlik, B., Kleinert, Maximilian, Klaus, S., Müller-Werdan, U. & Norman, K., 2022, In: Nutrients. 14, 19, 9 p., 4066.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Glucagon's metabolic action in health and disease
Zeigerer, A., Sekar, R., Kleinert, Maximilian, Nason, S., Habegger, K. M. & Müller, T. D., 2021, In: Comprehensive Physiology. 11, 2, p. 1759-1783 25 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmacological but not physiological GDF15 suppresses feeding and the motivation to exercise
Klein, A. B., Nicolaisen, T. S., Ørtenblad, N., Gejl, K. D., Jensen, R., Fritzen, A. M., Larsen, E. L., Karstoft, K., Poulsen, H. E., Morville, T., Sahl, R. E., Helge, J. W., Lund, J., Falk, S., Lyngbæk, M., Ellingsgaard, H., Pedersen, B. K., Lu, W., Finan, B., Jørgensen, S. B. & 5 others, , 2021, In: Nature Communications. 12, 9 p., 1041.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Small amounts of dietary medium-chain fatty acids protect against insulin resistance during caloric excess in humans
Lundsgaard, Anne-Marie, Fritzen, Andreas Mæchel, Sjøberg, K. A., Kleinert, Maximilian, Richter, Erik A. & Kiens, Bente, 2021, In: Diabetes. 70, 1, p. 91-98 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Spatiotemporal GLP-1 and GIP receptor signaling and trafficking/recycling dynamics induced by selected receptor mono- and dual-agonists
Novikoff, A., O'Brien, S. L., Bernecker, M., Grandl, G., Kleinert, Maximilian, Knerr, P. J., Stemmer, K., Klingenspor, M., Zeigerer, A., DiMarchi, R., Tschöp, M. H., Finan, B., Calebiro, D. & Müller, T. D., 2021, In: Molecular Metabolism. 49, 11 p., 101181.Research output: Contribution to journal › Journal article › Research › peer-review
The glucose-dependent insulinotropic polypeptide (GIP) regulates body weight and food intake via CNS-GIPR signaling
Zhang, Q., Delessa, C. T., Augustin, R., Bakhti, M., Colldén, G., Drucker, D. J., Feuchtinger, A., Caceres, C. G., Grandl, G., Harger, A., Herzig, S., Hofmann, S., Holleman, C. L., Jastroch, M., Keipert, S., Kleinert, M., Knerr, P. J., Kulaj, K., Legutko, B., Lickert, H. & 16 others, , 2021, In: Cell Metabolism. 33, 4, p. 833-844.e5 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of GDF15 as a myomitokine
Johann, K., Kleinert, Maximilian & Klaus, S., 2021, In: Cells. 10, 11, 16 p., 2990.Research output: Contribution to journal › Review › Research › peer-review
- 2020
- Published
A new FGF21 analog for the treatment of fatty liver disease
Kleinert, Maximilian & Müller, T. D., 2020, In: Diabetes. 69, 8, p. 1605-1607 3 p.Research output: Contribution to journal › Comment/debate › Research
- Published
ApoA-1 improves glucose tolerance by increasing glucose uptake into heart and skeletal muscle independently of AMPKα2
Fritzen, Andreas Mæchel, Domingo-Espín, J., Lundsgaard, Anne-Marie, Kleinert, Maximilian, Israelsen, I., Carl, Christian Strini, Nicolaisen, T. S., Kjøbsted, Rasmus, Jeppesen, J. F., Wojtaszewski, Jørgen F P, Lagerstedt, J. O. & Kiens, Bente, 2020, In: Molecular Metabolism. 35, 11 p., 100949.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucometabolic consequences of acute and prolonged inhibition of fatty acid oxidation
Lundsgaard, Anne-Marie, Fritzen, Andreas Mæchel, Nicolaisen, T. S., Carl, Christian Strini, Sjøberg, K. A., Raun, Steffen Henning, Klein, A. B., Sanchez-Quant, E., Langer, J., Ørskov, Cathrine, Clemmensen, Christoffer, Tschöp, M. H., Richter, Erik A., Kiens, Bente & Kleinert, Maximilian, 2020, In: Journal of Lipid Research. 61, 1, p. 10-19 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Growth factor-dependent and -independent activation of mTORC2
Knudsen, Jonas Roland, Fritzen, Andreas Mæchel, James, D. E., Jensen, Thomas Elbenhardt, Kleinert, Maximilian & Richter, Erik A., 2020, In: Trends in Endocrinology and Metabolism. 31, 1, p. 13-24 12 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Pharmacological targeting of α3β4 nicotinic receptors improves peripheral insulin sensitivity in mice with diet-induced obesity
Jall, S., De Angelis, M., Lundsgaard, Anne-Marie, Fritzen, Andreas Mæchel, Nicolaisen, T. S., Klein, A. B., Novikoff, A., Sachs, S., Richter, Erik A., Kiens, Bente, Schramm, K., Tschöp, M. H., Stemmer, K., Clemmensen, Christoffer, Müller, T. D. & Kleinert, Maximilian, 2020, In: Diabetologia. 63, 6, p. 1236-1247 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma proteome profiles treatment efficacy of incretin dual agonism in diet-induced obese female and male mice
Sachs, S., Niu, Lili, Geyer, P., Jall, S., Kleinert, Maximilian, Feuchtinger, A., Stemmer, K., Brielmeier, M., Finan, B., DiMarchi, R. D., Tschop, M. H., Albrechtsen, Nicolai Jacob Wewer, Mann, Matthias, Mueller, T. D. & Hofmann, S. M., 2020, In: Diabetes, Obesity and Metabolism. 23, 1, p. 195-207 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeted pharmacological therapy restores β-cell function for diabetes remission
Sachs, S., Bastidas-Ponce, A., Tritschler, S., Bakhti, M., Böttcher, A., Sánchez-Garrido, M. A., Tarquis-Medina, M., Kleinert, M., Fischer, K., Jall, S., Harger, A., Bader, E., Roscioni, S., Ussar, S., Feuchtinger, A., Yesildag, B., Neelakandhan, A., Jensen, C. B., Cornu, M., Yang, B. & 7 others, , 2020, In: Nature Metabolism. 2, 2, p. 192-209 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 23329589
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Targeted pharmacological therapy restores β-cell function for diabetes remission
Research output: Contribution to journal › Journal article › Research › peer-review
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463
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mTORC2 and AMPK differentially regulate muscle triglyceride content via Perilipin 3
Research output: Contribution to journal › Journal article › Research › peer-review
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Exercise increases circulating GDF15 in humans
Research output: Contribution to journal › Letter › Research › peer-review
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