Weight loss maintenance in overweight subjects on ad libitum diets with high or low protein content and glycemic index: the DIOGENES trial 12-months results

Research output: Contribution to journalJournal articleResearchpeer-review

Standard

Weight loss maintenance in overweight subjects on ad libitum diets with high or low protein content and glycemic index : the DIOGENES trial 12-months results. / Aller, E E J G; Larsen, Thomas Meinert; Holst, Claus; Karin Lindroos, A; Kafatos, A; Pfeiffer, A; Martinez, J A; Handjieva-Darlenska, T; Kunesova, M; Stender, Steen; Saris, W H M; Astrup, Arne; van Baak, M A.

In: International Journal of Obesity, Vol. 38, No. 12, 2014, p. 1511-1517.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Aller, EEJG, Larsen, TM, Holst, C, Karin Lindroos, A, Kafatos, A, Pfeiffer, A, Martinez, JA, Handjieva-Darlenska, T, Kunesova, M, Stender, S, Saris, WHM, Astrup, A & van Baak, MA 2014, 'Weight loss maintenance in overweight subjects on ad libitum diets with high or low protein content and glycemic index: the DIOGENES trial 12-months results', International Journal of Obesity, vol. 38, no. 12, pp. 1511-1517. https://doi.org/10.1038/ijo.2014.52

APA

Aller, E. E. J. G., Larsen, T. M., Holst, C., Karin Lindroos, A., Kafatos, A., Pfeiffer, A., ... van Baak, M. A. (2014). Weight loss maintenance in overweight subjects on ad libitum diets with high or low protein content and glycemic index: the DIOGENES trial 12-months results. International Journal of Obesity, 38(12), 1511-1517. https://doi.org/10.1038/ijo.2014.52

Vancouver

Aller EEJG, Larsen TM, Holst C, Karin Lindroos A, Kafatos A, Pfeiffer A et al. Weight loss maintenance in overweight subjects on ad libitum diets with high or low protein content and glycemic index: the DIOGENES trial 12-months results. International Journal of Obesity. 2014;38(12):1511-1517. https://doi.org/10.1038/ijo.2014.52

Author

Aller, E E J G ; Larsen, Thomas Meinert ; Holst, Claus ; Karin Lindroos, A ; Kafatos, A ; Pfeiffer, A ; Martinez, J A ; Handjieva-Darlenska, T ; Kunesova, M ; Stender, Steen ; Saris, W H M ; Astrup, Arne ; van Baak, M A. / Weight loss maintenance in overweight subjects on ad libitum diets with high or low protein content and glycemic index : the DIOGENES trial 12-months results. In: International Journal of Obesity. 2014 ; Vol. 38, No. 12. pp. 1511-1517.

Bibtex

@article{a5fedf3355664b6a979a4150c3a82d07,
title = "Weight loss maintenance in overweight subjects on ad libitum diets with high or low protein content and glycemic index: the DIOGENES trial 12-months results",
abstract = "Background:A high dietary protein (P) content and low glycemic index (GI) have been suggested to be beneficial for weight management, but long-term studies are scarce.Objective:The DIOGENES randomized clinical trial investigated the effect of P and GI on weight loss maintenance in overweight or obese adults in 8 centers across Europe. This study reports the 1-year results in 2 of the centers that extended the intervention to 1 year.Method:After an 8-week low calorie diet (LCD), 256 adults (BMI>27 kg/m(2)) were randomized to 5 ad libitum diets for 12 months: high P/low GI (HP/LGI), high P/high GI (HP/HGI), low P/low GI (LP/LGI), low P/high GI (LP/HGI) and a control diet. During the first 6 months foods were provided for free through a shop system, during the whole 12-month period subjects received guidance by a dietician. Primary outcome variable was the change in body weight over the 12-month intervention period.Results:During the LCD period subjects lost 11.2 (10.8, 12.0) kg (mean (95{\%} CI)). Average weight regain over the 12-month intervention period was 3.9 (95{\%} CI 3.0 to 4.8) kg. Subjects on the HP diets regained less weight than subjects on the LP diets. The difference in weight regain after 1 year was 2.0 (0.4, 3.6) kg (P=0.017) (completers analysis, N=139) or 2.8 (1.4, 4.1) kg (P",
author = "Aller, {E E J G} and Larsen, {Thomas Meinert} and Claus Holst and {Karin Lindroos}, A and A Kafatos and A Pfeiffer and Martinez, {J A} and T Handjieva-Darlenska and M Kunesova and Steen Stender and Saris, {W H M} and Arne Astrup and {van Baak}, {M A}",
note = "CURIS 2014 NEXS 097",
year = "2014",
doi = "10.1038/ijo.2014.52",
language = "English",
volume = "38",
pages = "1511--1517",
journal = "International Journal of Obesity",
issn = "0307-0565",
publisher = "nature publishing group",
number = "12",

}

RIS

TY - JOUR

T1 - Weight loss maintenance in overweight subjects on ad libitum diets with high or low protein content and glycemic index

T2 - the DIOGENES trial 12-months results

AU - Aller, E E J G

AU - Larsen, Thomas Meinert

AU - Holst, Claus

AU - Karin Lindroos, A

AU - Kafatos, A

AU - Pfeiffer, A

AU - Martinez, J A

AU - Handjieva-Darlenska, T

AU - Kunesova, M

AU - Stender, Steen

AU - Saris, W H M

AU - Astrup, Arne

AU - van Baak, M A

N1 - CURIS 2014 NEXS 097

PY - 2014

Y1 - 2014

N2 - Background:A high dietary protein (P) content and low glycemic index (GI) have been suggested to be beneficial for weight management, but long-term studies are scarce.Objective:The DIOGENES randomized clinical trial investigated the effect of P and GI on weight loss maintenance in overweight or obese adults in 8 centers across Europe. This study reports the 1-year results in 2 of the centers that extended the intervention to 1 year.Method:After an 8-week low calorie diet (LCD), 256 adults (BMI>27 kg/m(2)) were randomized to 5 ad libitum diets for 12 months: high P/low GI (HP/LGI), high P/high GI (HP/HGI), low P/low GI (LP/LGI), low P/high GI (LP/HGI) and a control diet. During the first 6 months foods were provided for free through a shop system, during the whole 12-month period subjects received guidance by a dietician. Primary outcome variable was the change in body weight over the 12-month intervention period.Results:During the LCD period subjects lost 11.2 (10.8, 12.0) kg (mean (95% CI)). Average weight regain over the 12-month intervention period was 3.9 (95% CI 3.0 to 4.8) kg. Subjects on the HP diets regained less weight than subjects on the LP diets. The difference in weight regain after 1 year was 2.0 (0.4, 3.6) kg (P=0.017) (completers analysis, N=139) or 2.8 (1.4, 4.1) kg (P

AB - Background:A high dietary protein (P) content and low glycemic index (GI) have been suggested to be beneficial for weight management, but long-term studies are scarce.Objective:The DIOGENES randomized clinical trial investigated the effect of P and GI on weight loss maintenance in overweight or obese adults in 8 centers across Europe. This study reports the 1-year results in 2 of the centers that extended the intervention to 1 year.Method:After an 8-week low calorie diet (LCD), 256 adults (BMI>27 kg/m(2)) were randomized to 5 ad libitum diets for 12 months: high P/low GI (HP/LGI), high P/high GI (HP/HGI), low P/low GI (LP/LGI), low P/high GI (LP/HGI) and a control diet. During the first 6 months foods were provided for free through a shop system, during the whole 12-month period subjects received guidance by a dietician. Primary outcome variable was the change in body weight over the 12-month intervention period.Results:During the LCD period subjects lost 11.2 (10.8, 12.0) kg (mean (95% CI)). Average weight regain over the 12-month intervention period was 3.9 (95% CI 3.0 to 4.8) kg. Subjects on the HP diets regained less weight than subjects on the LP diets. The difference in weight regain after 1 year was 2.0 (0.4, 3.6) kg (P=0.017) (completers analysis, N=139) or 2.8 (1.4, 4.1) kg (P

U2 - 10.1038/ijo.2014.52

DO - 10.1038/ijo.2014.52

M3 - Journal article

C2 - 24675714

VL - 38

SP - 1511

EP - 1517

JO - International Journal of Obesity

JF - International Journal of Obesity

SN - 0307-0565

IS - 12

ER -

ID: 105853128