The effect of three different ad libitum diets for weight loss maintenance: a randomized 18-month trial

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The effect of three different ad libitum diets for weight loss maintenance: a randomized 18-month trial. / Due, Anette Pia; Larsen, Thomas Meinert; Mu, Huiling; Hermansen, Kjeld; Stender, Steen; Toubro, Søren; Allison, David B; Astrup, Arne.

In: European Journal of Nutrition, Vol. 56, No. 2, 2017, p. 727-738.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Due, AP, Larsen, TM, Mu, H, Hermansen, K, Stender, S, Toubro, S, Allison, DB & Astrup, A 2017, 'The effect of three different ad libitum diets for weight loss maintenance: a randomized 18-month trial', European Journal of Nutrition, vol. 56, no. 2, pp. 727-738. https://doi.org/10.1007/s00394-015-1116-6

APA

Due, A. P., Larsen, T. M., Mu, H., Hermansen, K., Stender, S., Toubro, S., ... Astrup, A. (2017). The effect of three different ad libitum diets for weight loss maintenance: a randomized 18-month trial. European Journal of Nutrition, 56(2), 727-738. https://doi.org/10.1007/s00394-015-1116-6

Vancouver

Due AP, Larsen TM, Mu H, Hermansen K, Stender S, Toubro S et al. The effect of three different ad libitum diets for weight loss maintenance: a randomized 18-month trial. European Journal of Nutrition. 2017;56(2):727-738. https://doi.org/10.1007/s00394-015-1116-6

Author

Due, Anette Pia ; Larsen, Thomas Meinert ; Mu, Huiling ; Hermansen, Kjeld ; Stender, Steen ; Toubro, Søren ; Allison, David B ; Astrup, Arne. / The effect of three different ad libitum diets for weight loss maintenance: a randomized 18-month trial. In: European Journal of Nutrition. 2017 ; Vol. 56, No. 2. pp. 727-738.

Bibtex

@article{0279101bbd25495995cae668c680bcc2,
title = "The effect of three different ad libitum diets for weight loss maintenance: a randomized 18-month trial",
abstract = "PURPOSE: To test the effect of three diets in their ability to sustain weight loss and improve type 2 diabetes (T2D) and cardiovascular disease (CVD) risk markers after 18-month intervention.METHODS: Following a ≥8 {\%} weight loss, 131 healthy, overweight/obese (BMI ± SD 31.5 ± 2.6 kg/m(2)) men (n = 55) and women (n = 76) aged 28.2 ± 4.8 years were randomized to either 1. Moderate fat (40 E{\%}) with 20 E{\%} MUFA and low in glycemic index (GI) (MUFA, n = 54), 2. Low fat (25 E{\%}) and medium in GI (LF, n = 51) or 3. Control (35 E{\%} fat) and high in GI (CTR, n = 26) all with similar protein content, and all provided ad libitum. First 6-month intervention with 100 {\%} food provision (previously reported) following 12 months of moderately intensive intervention with 20 {\%} food provision now reported.RESULTS: Attrition rate was higher in MUFA (63 {\%}) than in LF (37 {\%}, P = 0.019) and CTR (42 {\%}, P = 0.09) group. Weight regain in completers was not different between groups (mean ± SEM), MUFA 7.1 ± 2.1 {\%} versus LF 5.6 ± 1.3 {\%} versus CTR 7.2 ± 1.5 {\%}, nor was body fat regain, MUFA 4.8 ± 1.0 {\%} versus LF 4.7 ± 0.8 {\%} versus CTR 5.7 ± 0.6 {\%}. The MUFA group reduced LDL/HDL ratio by -0.47 ± 0.09 compared with -0.23 ± 0.11 in LF (P < 0.05) and 0.06 ± 0.14 (P < 0.005) in CTR groups.CONCLUSIONS: Weight regain or body composition did not differ between diets over 18 months. No effects on risk markers for T2D or CVD were found, with the exception of an improvement in the LDL/HDL ratio by the MUFA diet compared to the CTR diet. The LF diet was generally more satisfactory and the MUFA diet seemed more difficult to follow.",
keywords = "Faculty of Science, Weight loss, Weight maintenance, Mediterraenean diet, Cardiovascular disease, Dietary intervention",
author = "Due, {Anette Pia} and Larsen, {Thomas Meinert} and Huiling Mu and Kjeld Hermansen and Steen Stender and S{\o}ren Toubro and Allison, {David B} and Arne Astrup",
note = "CURIS 2017 NEXS 074",
year = "2017",
doi = "10.1007/s00394-015-1116-6",
language = "English",
volume = "56",
pages = "727--738",
journal = "European Journal of Nutrition",
issn = "1436-6207",
publisher = "Springer Medizin",
number = "2",

}

RIS

TY - JOUR

T1 - The effect of three different ad libitum diets for weight loss maintenance: a randomized 18-month trial

AU - Due, Anette Pia

AU - Larsen, Thomas Meinert

AU - Mu, Huiling

AU - Hermansen, Kjeld

AU - Stender, Steen

AU - Toubro, Søren

AU - Allison, David B

AU - Astrup, Arne

N1 - CURIS 2017 NEXS 074

PY - 2017

Y1 - 2017

N2 - PURPOSE: To test the effect of three diets in their ability to sustain weight loss and improve type 2 diabetes (T2D) and cardiovascular disease (CVD) risk markers after 18-month intervention.METHODS: Following a ≥8 % weight loss, 131 healthy, overweight/obese (BMI ± SD 31.5 ± 2.6 kg/m(2)) men (n = 55) and women (n = 76) aged 28.2 ± 4.8 years were randomized to either 1. Moderate fat (40 E%) with 20 E% MUFA and low in glycemic index (GI) (MUFA, n = 54), 2. Low fat (25 E%) and medium in GI (LF, n = 51) or 3. Control (35 E% fat) and high in GI (CTR, n = 26) all with similar protein content, and all provided ad libitum. First 6-month intervention with 100 % food provision (previously reported) following 12 months of moderately intensive intervention with 20 % food provision now reported.RESULTS: Attrition rate was higher in MUFA (63 %) than in LF (37 %, P = 0.019) and CTR (42 %, P = 0.09) group. Weight regain in completers was not different between groups (mean ± SEM), MUFA 7.1 ± 2.1 % versus LF 5.6 ± 1.3 % versus CTR 7.2 ± 1.5 %, nor was body fat regain, MUFA 4.8 ± 1.0 % versus LF 4.7 ± 0.8 % versus CTR 5.7 ± 0.6 %. The MUFA group reduced LDL/HDL ratio by -0.47 ± 0.09 compared with -0.23 ± 0.11 in LF (P < 0.05) and 0.06 ± 0.14 (P < 0.005) in CTR groups.CONCLUSIONS: Weight regain or body composition did not differ between diets over 18 months. No effects on risk markers for T2D or CVD were found, with the exception of an improvement in the LDL/HDL ratio by the MUFA diet compared to the CTR diet. The LF diet was generally more satisfactory and the MUFA diet seemed more difficult to follow.

AB - PURPOSE: To test the effect of three diets in their ability to sustain weight loss and improve type 2 diabetes (T2D) and cardiovascular disease (CVD) risk markers after 18-month intervention.METHODS: Following a ≥8 % weight loss, 131 healthy, overweight/obese (BMI ± SD 31.5 ± 2.6 kg/m(2)) men (n = 55) and women (n = 76) aged 28.2 ± 4.8 years were randomized to either 1. Moderate fat (40 E%) with 20 E% MUFA and low in glycemic index (GI) (MUFA, n = 54), 2. Low fat (25 E%) and medium in GI (LF, n = 51) or 3. Control (35 E% fat) and high in GI (CTR, n = 26) all with similar protein content, and all provided ad libitum. First 6-month intervention with 100 % food provision (previously reported) following 12 months of moderately intensive intervention with 20 % food provision now reported.RESULTS: Attrition rate was higher in MUFA (63 %) than in LF (37 %, P = 0.019) and CTR (42 %, P = 0.09) group. Weight regain in completers was not different between groups (mean ± SEM), MUFA 7.1 ± 2.1 % versus LF 5.6 ± 1.3 % versus CTR 7.2 ± 1.5 %, nor was body fat regain, MUFA 4.8 ± 1.0 % versus LF 4.7 ± 0.8 % versus CTR 5.7 ± 0.6 %. The MUFA group reduced LDL/HDL ratio by -0.47 ± 0.09 compared with -0.23 ± 0.11 in LF (P < 0.05) and 0.06 ± 0.14 (P < 0.005) in CTR groups.CONCLUSIONS: Weight regain or body composition did not differ between diets over 18 months. No effects on risk markers for T2D or CVD were found, with the exception of an improvement in the LDL/HDL ratio by the MUFA diet compared to the CTR diet. The LF diet was generally more satisfactory and the MUFA diet seemed more difficult to follow.

KW - Faculty of Science

KW - Weight loss

KW - Weight maintenance

KW - Mediterraenean diet

KW - Cardiovascular disease

KW - Dietary intervention

U2 - 10.1007/s00394-015-1116-6

DO - 10.1007/s00394-015-1116-6

M3 - Journal article

C2 - 26659070

VL - 56

SP - 727

EP - 738

JO - European Journal of Nutrition

JF - European Journal of Nutrition

SN - 1436-6207

IS - 2

ER -

ID: 153052655