The effect of a home delivery meal service of energy- and protein-rich meals on quality of life in malnourished outpatients suffering from lung cancer: A randomized controlled trial

Research output: Contribution to journalJournal article

  • Eva Leedo
  • Josephine Gade
  • Sabrina Granov
  • Anders Mellemgaard
  • Tobias Wirenfeldt Klausen
  • Katrine Rask
  • Astrup, Arne

Undernutrition is prevalent in cancer patients and associated with increased incidence of complications and mortality. We investigated the effects of a home delivery meal service, providing a selection of energy-dense, protein-rich meals, on quality of life (QoL) in malnourished lung cancer patients. Forty lung cancer patients with nutritional risk score ≥3 (NRS-2002) were randomized to control or intervention. The intervention group was offered energy- and protein-rich main meals and snacks, delivered 3 times per week. The control group continued their habitual diet. Primary endpoint, QoL, and secondary endpoints were assessed at baseline, and after 6 and 12 wk. Data on unplanned readmissions, length of hospital stay, and mortality were collected 3 and 6 mo post-intervention. Intervention group improved standard Chair Stand Test (30-s CST) after 6 and 12 wk (P < 0.01) compared to control. Intervention exerted a significant positive effect on performance score after 12 wk (P = 0.047). Increased energy and protein intakes were strongly associated with improved QoL, functional score, hand grip strength, symptom and performance scores. Food delivery service with energy- and protein-rich main meals and snacks can improve lower body strength and performance status in malnourished lung cancer patients.

Original languageEnglish
JournalNutrition and Cancer
Volume69
Issue number3
Pages (from-to)444-453
Number of pages10
ISSN0163-5581
DOIs
Publication statusPublished - 2017

    Research areas

  • Journal Article

ID: 174402404