Reduced neuromuscular performance in amenorrheic elite endurance athletes

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Reduced neuromuscular performance in amenorrheic elite endurance athletes. / Tornberg, Åsa B; Melin, Anna; Manderson Koivula, Fiona; Johansson, Anders; Skouby, Sven O; Faber, Jens; Sjödin, Anders Mikael.

In: Medicine and Science in Sports and Exercise, Vol. 49, No. 12, 2017, p. 2478-2485.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Tornberg, ÅB, Melin, A, Manderson Koivula, F, Johansson, A, Skouby, SO, Faber, J & Sjödin, AM 2017, 'Reduced neuromuscular performance in amenorrheic elite endurance athletes', Medicine and Science in Sports and Exercise, vol. 49, no. 12, pp. 2478-2485. https://doi.org/10.1249/MSS.0000000000001383

APA

Tornberg, Å. B., Melin, A., Manderson Koivula, F., Johansson, A., Skouby, S. O., Faber, J., & Sjödin, A. M. (2017). Reduced neuromuscular performance in amenorrheic elite endurance athletes. Medicine and Science in Sports and Exercise, 49(12), 2478-2485. https://doi.org/10.1249/MSS.0000000000001383

Vancouver

Tornberg ÅB, Melin A, Manderson Koivula F, Johansson A, Skouby SO, Faber J et al. Reduced neuromuscular performance in amenorrheic elite endurance athletes. Medicine and Science in Sports and Exercise. 2017;49(12):2478-2485. https://doi.org/10.1249/MSS.0000000000001383

Author

Tornberg, Åsa B ; Melin, Anna ; Manderson Koivula, Fiona ; Johansson, Anders ; Skouby, Sven O ; Faber, Jens ; Sjödin, Anders Mikael. / Reduced neuromuscular performance in amenorrheic elite endurance athletes. In: Medicine and Science in Sports and Exercise. 2017 ; Vol. 49, No. 12. pp. 2478-2485.

Bibtex

@article{25b83cf4e0d84f73b2883e2592014981,
title = "Reduced neuromuscular performance in amenorrheic elite endurance athletes",
abstract = "INTRODUCTION: Secondary functional hypothalamic amenorrhea (SFHA) is common among female athletes, especially in weight-sensitive sports. The aim of this study was to investigate the link between SFHA and neuromuscular performance in elite endurance athletes. METHODS: Sixteen eumenorrheic (EUM) and 14 SFHA athletes from national teams and competitive clubs participated. Methods included gynecological examination; body composition (DXA);; resting metabolic rate and work efficiency; exercise capacity; knee muscular strength (KMS) and knee muscular endurance (KME); reaction time (RT); blood sampling performed on the 3rd-5th day of the menstrual cycle, and 7-day assessment of energy availability. RESULTS: SFHA athletes had lower estrogen (0.12 ±0.03 vs. 0.17 ±0.09 nmol/L, p<0.05), triiodothyronine (T3) (1.4 ±0.2 vs. 1.7 ±0.3 nmol/L, p<0.01), and blood glucose (3.8 ±0.3 vs 4.4 ±0.3 mmol/L, p<0.001) but higher cortisol levels (564 ±111 vs. 400 ±140 nmol/L, p<0.05) compared to EUM athletes. SFHA had a lower body weight (55.0 ±5.8 vs. 60.6 ±7.1 kg, p<0.05), but no difference in exercise capacity between groups was found (56.4 ±5.8 vs. 54.0 ±6.3 ml O2/min/kg). RT was 7{\%} longer, and KMS and KME were 11{\%} and 20{\%} lower compared to EUM athletes. RT was negatively associated with glucose (r=-0.40, p<0.05), T3 (r=-0.37, p<0.05) and estrogen (r=-0.43, p<0.05), but positively associated with cortisol (r=0.38, p<0.05). KMS and KME correlated with fat free mass in the tested leg (FFMleg)(r=0.52, p<0.001; r=0.58, p<0.001) but were negatively associated with cortisol (r=-0.42, p<0.05; r=-0.59, p<0.001). FFMleg explained differences in KMS, while reproductive function and FFMleg independently explained the variability in KME. CONCLUSION: We found lower neuromuscular performance among SFHA compared to EUM athletes linked to a lower FFMleg, glucose, estrogen, T3 and elevated cortisol levels.",
keywords = "Faculty of Science, Amenorrhea, Energy availability, Fat free mass, Blood glucose, Cortisol, T3",
author = "Tornberg, {{\AA}sa B} and Anna Melin and {Manderson Koivula}, Fiona and Anders Johansson and Skouby, {Sven O} and Jens Faber and Sj{\"o}din, {Anders Mikael}",
note = "CURIS 2017 NEXS 317",
year = "2017",
doi = "10.1249/MSS.0000000000001383",
language = "English",
volume = "49",
pages = "2478--2485",
journal = "Medicine and Science in Sports and Exercise",
issn = "0195-9131",
publisher = "Lippincott Williams & Wilkins",
number = "12",

}

RIS

TY - JOUR

T1 - Reduced neuromuscular performance in amenorrheic elite endurance athletes

AU - Tornberg, Åsa B

AU - Melin, Anna

AU - Manderson Koivula, Fiona

AU - Johansson, Anders

AU - Skouby, Sven O

AU - Faber, Jens

AU - Sjödin, Anders Mikael

N1 - CURIS 2017 NEXS 317

PY - 2017

Y1 - 2017

N2 - INTRODUCTION: Secondary functional hypothalamic amenorrhea (SFHA) is common among female athletes, especially in weight-sensitive sports. The aim of this study was to investigate the link between SFHA and neuromuscular performance in elite endurance athletes. METHODS: Sixteen eumenorrheic (EUM) and 14 SFHA athletes from national teams and competitive clubs participated. Methods included gynecological examination; body composition (DXA);; resting metabolic rate and work efficiency; exercise capacity; knee muscular strength (KMS) and knee muscular endurance (KME); reaction time (RT); blood sampling performed on the 3rd-5th day of the menstrual cycle, and 7-day assessment of energy availability. RESULTS: SFHA athletes had lower estrogen (0.12 ±0.03 vs. 0.17 ±0.09 nmol/L, p<0.05), triiodothyronine (T3) (1.4 ±0.2 vs. 1.7 ±0.3 nmol/L, p<0.01), and blood glucose (3.8 ±0.3 vs 4.4 ±0.3 mmol/L, p<0.001) but higher cortisol levels (564 ±111 vs. 400 ±140 nmol/L, p<0.05) compared to EUM athletes. SFHA had a lower body weight (55.0 ±5.8 vs. 60.6 ±7.1 kg, p<0.05), but no difference in exercise capacity between groups was found (56.4 ±5.8 vs. 54.0 ±6.3 ml O2/min/kg). RT was 7% longer, and KMS and KME were 11% and 20% lower compared to EUM athletes. RT was negatively associated with glucose (r=-0.40, p<0.05), T3 (r=-0.37, p<0.05) and estrogen (r=-0.43, p<0.05), but positively associated with cortisol (r=0.38, p<0.05). KMS and KME correlated with fat free mass in the tested leg (FFMleg)(r=0.52, p<0.001; r=0.58, p<0.001) but were negatively associated with cortisol (r=-0.42, p<0.05; r=-0.59, p<0.001). FFMleg explained differences in KMS, while reproductive function and FFMleg independently explained the variability in KME. CONCLUSION: We found lower neuromuscular performance among SFHA compared to EUM athletes linked to a lower FFMleg, glucose, estrogen, T3 and elevated cortisol levels.

AB - INTRODUCTION: Secondary functional hypothalamic amenorrhea (SFHA) is common among female athletes, especially in weight-sensitive sports. The aim of this study was to investigate the link between SFHA and neuromuscular performance in elite endurance athletes. METHODS: Sixteen eumenorrheic (EUM) and 14 SFHA athletes from national teams and competitive clubs participated. Methods included gynecological examination; body composition (DXA);; resting metabolic rate and work efficiency; exercise capacity; knee muscular strength (KMS) and knee muscular endurance (KME); reaction time (RT); blood sampling performed on the 3rd-5th day of the menstrual cycle, and 7-day assessment of energy availability. RESULTS: SFHA athletes had lower estrogen (0.12 ±0.03 vs. 0.17 ±0.09 nmol/L, p<0.05), triiodothyronine (T3) (1.4 ±0.2 vs. 1.7 ±0.3 nmol/L, p<0.01), and blood glucose (3.8 ±0.3 vs 4.4 ±0.3 mmol/L, p<0.001) but higher cortisol levels (564 ±111 vs. 400 ±140 nmol/L, p<0.05) compared to EUM athletes. SFHA had a lower body weight (55.0 ±5.8 vs. 60.6 ±7.1 kg, p<0.05), but no difference in exercise capacity between groups was found (56.4 ±5.8 vs. 54.0 ±6.3 ml O2/min/kg). RT was 7% longer, and KMS and KME were 11% and 20% lower compared to EUM athletes. RT was negatively associated with glucose (r=-0.40, p<0.05), T3 (r=-0.37, p<0.05) and estrogen (r=-0.43, p<0.05), but positively associated with cortisol (r=0.38, p<0.05). KMS and KME correlated with fat free mass in the tested leg (FFMleg)(r=0.52, p<0.001; r=0.58, p<0.001) but were negatively associated with cortisol (r=-0.42, p<0.05; r=-0.59, p<0.001). FFMleg explained differences in KMS, while reproductive function and FFMleg independently explained the variability in KME. CONCLUSION: We found lower neuromuscular performance among SFHA compared to EUM athletes linked to a lower FFMleg, glucose, estrogen, T3 and elevated cortisol levels.

KW - Faculty of Science

KW - Amenorrhea

KW - Energy availability

KW - Fat free mass

KW - Blood glucose

KW - Cortisol

KW - T3

U2 - 10.1249/MSS.0000000000001383

DO - 10.1249/MSS.0000000000001383

M3 - Journal article

C2 - 28723842

AN - SCOPUS:85025160119

VL - 49

SP - 2478

EP - 2485

JO - Medicine and Science in Sports and Exercise

JF - Medicine and Science in Sports and Exercise

SN - 0195-9131

IS - 12

ER -

ID: 182224709