Protein supplementation combined with low-intensity resistance training in geriatric medical patients during and after hospitalization: A randomized, double-blind, multicenter trial

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Josephine Gade, Anne Marie Beck, Hanne Elkjær Andersen, Britt Christensen, Finn Rønholt, Tobias W Klausen, Anders Vinther, Arne Astrup

Sarcopenia (loss of muscle mass/strength) burdens many older adults - hospitalized older adults being particularly vulnerable. Treating the condition, protein-supplementation (PrS) and resistance-training (RT) may act synergistically. Therefore, this block-randomised, double-blind, multicentre intervention study, recruiting geriatric patients >70 years from three Medical Departments, investigated the effect of PrS combined with RT during hospitalization and 12 weeks after discharge. Participants were randomly allocated (1:1) to receive PrS (totally 27.5 g whey protein/day, ≈2000 kJ/day) or iso-energetic placebo-products (0.05). In conclusion, PrS increasing total protein intake by 0.4 and 0.2 g/kg/d during hospitalization and after discharge, respectively, does not seem to increase the adaptive response to low intensity/volume RT in geriatric medical patients.

Original languageEnglish
JournalBritish Journal of Nutrition
ISSN0007-1145
DOIs
Publication statusAccepted/In press - 24 Jul 2019

    Research areas

  • The Faculty of Science - Sarcopenia, Older adults, Acutely ill, Milk-based, Resistance exercise training, Muscle strength, Muscle mass, Physical function, Rehabilitation

ID: 224899403