Milk and dairy consumption and risk of cardiovascular diseases and all-cause mortality: dose-response meta-analysis of prospective cohort studies

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Milk and dairy consumption and risk of cardiovascular diseases and all-cause mortality : dose-response meta-analysis of prospective cohort studies. / Guo, Jing; Astrup, Arne; Lovegrove, Julie A; Gijsbers, Lieke; Givens, David I; Soedamah-Muthu, Sabita S.

In: European Journal of Epidemiology, Vol. 32, No. 4, 2017, p. 269-287.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Guo, J, Astrup, A, Lovegrove, JA, Gijsbers, L, Givens, DI & Soedamah-Muthu, SS 2017, 'Milk and dairy consumption and risk of cardiovascular diseases and all-cause mortality: dose-response meta-analysis of prospective cohort studies', European Journal of Epidemiology, vol. 32, no. 4, pp. 269-287. https://doi.org/10.1007/s10654-017-0243-1

APA

Guo, J., Astrup, A., Lovegrove, J. A., Gijsbers, L., Givens, D. I., & Soedamah-Muthu, S. S. (2017). Milk and dairy consumption and risk of cardiovascular diseases and all-cause mortality: dose-response meta-analysis of prospective cohort studies. European Journal of Epidemiology, 32(4), 269-287. https://doi.org/10.1007/s10654-017-0243-1

Vancouver

Guo J, Astrup A, Lovegrove JA, Gijsbers L, Givens DI, Soedamah-Muthu SS. Milk and dairy consumption and risk of cardiovascular diseases and all-cause mortality: dose-response meta-analysis of prospective cohort studies. European Journal of Epidemiology. 2017;32(4):269-287. https://doi.org/10.1007/s10654-017-0243-1

Author

Guo, Jing ; Astrup, Arne ; Lovegrove, Julie A ; Gijsbers, Lieke ; Givens, David I ; Soedamah-Muthu, Sabita S. / Milk and dairy consumption and risk of cardiovascular diseases and all-cause mortality : dose-response meta-analysis of prospective cohort studies. In: European Journal of Epidemiology. 2017 ; Vol. 32, No. 4. pp. 269-287.

Bibtex

@article{728b1ee11e72494eb5c37fbb30f25b13,
title = "Milk and dairy consumption and risk of cardiovascular diseases and all-cause mortality: dose-response meta-analysis of prospective cohort studies",
abstract = "With a growing number of prospective cohort studies, an updated dose-response meta-analysis of milk and dairy products with all-cause mortality, coronary heart disease (CHD) or cardiovascular disease (CVD) have been conducted. PubMed, Embase and Scopus were searched for articles published up to September 2016. Random-effect meta-analyses with summarised dose-response data were performed for total (high-fat/low-fat) dairy, milk, fermented dairy, cheese and yogurt. Non-linear associations were investigated using the spine models and heterogeneity by subgroup analyses. A total of 29 cohort studies were available for meta-analysis, with 938,465 participants and 93,158 mortality, 28,419 CHD and 25,416 CVD cases. No associations were found for total (high-fat/low-fat) dairy, and milk with the health outcomes of mortality, CHD or CVD. Inverse associations were found between total fermented dairy (included sour milk products, cheese or yogurt; per 20 g/day) with mortality (RR 0.98, 95{\%} CI 0.97-0.99; I(2) = 94.4{\%}) and CVD risk (RR 0.98, 95{\%} CI 0.97-0.99; I(2) = 87.5{\%}). Further analyses of individual fermented dairy of cheese and yogurt showed cheese to have a 2{\%} lower risk of CVD (RR 0.98, 95{\%} CI 0.95-1.00; I(2) = 82.6{\%}) per 10 g/day, but not yogurt. All of these marginally inverse associations of totally fermented dairy and cheese were attenuated in sensitivity analyses by removing one large Swedish study. This meta-analysis combining data from 29 prospective cohort studies demonstrated neutral associations between dairy products and cardiovascular and all-cause mortality. For future studies it is important to investigate in more detail how dairy products can be replaced by other foods.",
keywords = "Dairy, Milk, Fermented dairy, All-cause mortality, Cardiovascular disease, Dose-response meta-analysis",
author = "Jing Guo and Arne Astrup and Lovegrove, {Julie A} and Lieke Gijsbers and Givens, {David I} and Soedamah-Muthu, {Sabita S}",
note = "CURIS 2017 NEXS 105",
year = "2017",
doi = "10.1007/s10654-017-0243-1",
language = "English",
volume = "32",
pages = "269--287",
journal = "European Journal of Epidemiology",
issn = "0393-2990",
publisher = "Springer",
number = "4",

}

RIS

TY - JOUR

T1 - Milk and dairy consumption and risk of cardiovascular diseases and all-cause mortality

T2 - dose-response meta-analysis of prospective cohort studies

AU - Guo, Jing

AU - Astrup, Arne

AU - Lovegrove, Julie A

AU - Gijsbers, Lieke

AU - Givens, David I

AU - Soedamah-Muthu, Sabita S

N1 - CURIS 2017 NEXS 105

PY - 2017

Y1 - 2017

N2 - With a growing number of prospective cohort studies, an updated dose-response meta-analysis of milk and dairy products with all-cause mortality, coronary heart disease (CHD) or cardiovascular disease (CVD) have been conducted. PubMed, Embase and Scopus were searched for articles published up to September 2016. Random-effect meta-analyses with summarised dose-response data were performed for total (high-fat/low-fat) dairy, milk, fermented dairy, cheese and yogurt. Non-linear associations were investigated using the spine models and heterogeneity by subgroup analyses. A total of 29 cohort studies were available for meta-analysis, with 938,465 participants and 93,158 mortality, 28,419 CHD and 25,416 CVD cases. No associations were found for total (high-fat/low-fat) dairy, and milk with the health outcomes of mortality, CHD or CVD. Inverse associations were found between total fermented dairy (included sour milk products, cheese or yogurt; per 20 g/day) with mortality (RR 0.98, 95% CI 0.97-0.99; I(2) = 94.4%) and CVD risk (RR 0.98, 95% CI 0.97-0.99; I(2) = 87.5%). Further analyses of individual fermented dairy of cheese and yogurt showed cheese to have a 2% lower risk of CVD (RR 0.98, 95% CI 0.95-1.00; I(2) = 82.6%) per 10 g/day, but not yogurt. All of these marginally inverse associations of totally fermented dairy and cheese were attenuated in sensitivity analyses by removing one large Swedish study. This meta-analysis combining data from 29 prospective cohort studies demonstrated neutral associations between dairy products and cardiovascular and all-cause mortality. For future studies it is important to investigate in more detail how dairy products can be replaced by other foods.

AB - With a growing number of prospective cohort studies, an updated dose-response meta-analysis of milk and dairy products with all-cause mortality, coronary heart disease (CHD) or cardiovascular disease (CVD) have been conducted. PubMed, Embase and Scopus were searched for articles published up to September 2016. Random-effect meta-analyses with summarised dose-response data were performed for total (high-fat/low-fat) dairy, milk, fermented dairy, cheese and yogurt. Non-linear associations were investigated using the spine models and heterogeneity by subgroup analyses. A total of 29 cohort studies were available for meta-analysis, with 938,465 participants and 93,158 mortality, 28,419 CHD and 25,416 CVD cases. No associations were found for total (high-fat/low-fat) dairy, and milk with the health outcomes of mortality, CHD or CVD. Inverse associations were found between total fermented dairy (included sour milk products, cheese or yogurt; per 20 g/day) with mortality (RR 0.98, 95% CI 0.97-0.99; I(2) = 94.4%) and CVD risk (RR 0.98, 95% CI 0.97-0.99; I(2) = 87.5%). Further analyses of individual fermented dairy of cheese and yogurt showed cheese to have a 2% lower risk of CVD (RR 0.98, 95% CI 0.95-1.00; I(2) = 82.6%) per 10 g/day, but not yogurt. All of these marginally inverse associations of totally fermented dairy and cheese were attenuated in sensitivity analyses by removing one large Swedish study. This meta-analysis combining data from 29 prospective cohort studies demonstrated neutral associations between dairy products and cardiovascular and all-cause mortality. For future studies it is important to investigate in more detail how dairy products can be replaced by other foods.

KW - Dairy

KW - Milk

KW - Fermented dairy

KW - All-cause mortality

KW - Cardiovascular disease

KW - Dose-response meta-analysis

U2 - 10.1007/s10654-017-0243-1

DO - 10.1007/s10654-017-0243-1

M3 - Journal article

C2 - 28374228

VL - 32

SP - 269

EP - 287

JO - European Journal of Epidemiology

JF - European Journal of Epidemiology

SN - 0393-2990

IS - 4

ER -

ID: 174902400