Influence of immune and nutritional biomarkers on illness risk during interval training

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Influence of immune and nutritional biomarkers on illness risk during interval training. / Hanstock, Helen G; Govus, Andrew D; Stenqvist, Thomas B; Melin, Anna Katarina; Sylta, Øystein; Torstveit, Monica Klungland.

In: International Journal of Sports Physiology and Performance, 29.04.2019.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Hanstock, HG, Govus, AD, Stenqvist, TB, Melin, AK, Sylta, Ø & Torstveit, MK 2019, 'Influence of immune and nutritional biomarkers on illness risk during interval training' International Journal of Sports Physiology and Performance. https://doi.org/10.1123/ijspp.2018-0527

APA

Hanstock, H. G., Govus, A. D., Stenqvist, T. B., Melin, A. K., Sylta, Ø., & Torstveit, M. K. (Accepted/In press). Influence of immune and nutritional biomarkers on illness risk during interval training. International Journal of Sports Physiology and Performance. https://doi.org/10.1123/ijspp.2018-0527

Vancouver

Hanstock HG, Govus AD, Stenqvist TB, Melin AK, Sylta Ø, Torstveit MK. Influence of immune and nutritional biomarkers on illness risk during interval training. International Journal of Sports Physiology and Performance. 2019 Apr 29. https://doi.org/10.1123/ijspp.2018-0527

Author

Hanstock, Helen G ; Govus, Andrew D ; Stenqvist, Thomas B ; Melin, Anna Katarina ; Sylta, Øystein ; Torstveit, Monica Klungland. / Influence of immune and nutritional biomarkers on illness risk during interval training. In: International Journal of Sports Physiology and Performance. 2019.

Bibtex

@article{cfb428c8bf5a47689fea5717e01d54c6,
title = "Influence of immune and nutritional biomarkers on illness risk during interval training",
abstract = "Purpose: This study explored whether three different HIT prescriptions influence multiple health-related biomarkers and whether biomarker responses to HIT were associated with upper respiratory illness (URI) risk.Methods: Twenty-five male cyclists and triathletes were randomised to three HIT groups and completed twelve HIT sessions over four weeks. Peak oxygen consumption (V̇O2peak) was determined using an incremental cycling protocol, while resting serum biomarkers (cortisol, testosterone, 25(OH)D and ferritin), salivary immunoglobulin-A (s-IgA) and energy availability (EA) were assessed before and after the training intervention. Participants self-reported upper respiratory symptoms during the intervention and episodes of URI were identified retrospectively.Results: Fourteen athletes reported URIs, but there were no differences in incidence, duration or severity between groups. Increased risk of URI was associated with higher s-IgA secretion rates (odds ratio=0.90, 90{\%} CI:0.83-0.97). Lower pre-intervention cortisol and higher EA predicted a 4{\%} increase in URI duration. Participants with higher V̇O2peak reported higher total symptom scores (incidence rate ratio=1.07, 90{\%} CI:1.01-1.13).Conclusions: Although multiple biomarkers were weakly associated with risk of URI, the direction of associations between s-IgA, cortisol, EA and URI risk were inverse to previous observations and physiological rationale. There was a cluster of URIs within the first week of the training intervention, but no samples were collected at this time-point. Future studies should incorporate more frequent sample time-points, especially around the onset of new training regimes, and include athletes with suspected or known nutritional deficiencies.",
keywords = "The Faculty of Science, Endurance athletes, HIT, Immunity, Training load, URT1",
author = "Hanstock, {Helen G} and Govus, {Andrew D} and Stenqvist, {Thomas B} and Melin, {Anna Katarina} and {\O}ystein Sylta and Torstveit, {Monica Klungland}",
note = "Afventer publicering som [Epub ahead of print] samt tildeling af CURIS-nummer.",
year = "2019",
month = "4",
day = "29",
doi = "10.1123/ijspp.2018-0527",
language = "English",
journal = "International Journal of Sports Physiology and Performance",
issn = "1555-0265",
publisher = "Human Kinetics, Inc",

}

RIS

TY - JOUR

T1 - Influence of immune and nutritional biomarkers on illness risk during interval training

AU - Hanstock, Helen G

AU - Govus, Andrew D

AU - Stenqvist, Thomas B

AU - Melin, Anna Katarina

AU - Sylta, Øystein

AU - Torstveit, Monica Klungland

N1 - Afventer publicering som [Epub ahead of print] samt tildeling af CURIS-nummer.

PY - 2019/4/29

Y1 - 2019/4/29

N2 - Purpose: This study explored whether three different HIT prescriptions influence multiple health-related biomarkers and whether biomarker responses to HIT were associated with upper respiratory illness (URI) risk.Methods: Twenty-five male cyclists and triathletes were randomised to three HIT groups and completed twelve HIT sessions over four weeks. Peak oxygen consumption (V̇O2peak) was determined using an incremental cycling protocol, while resting serum biomarkers (cortisol, testosterone, 25(OH)D and ferritin), salivary immunoglobulin-A (s-IgA) and energy availability (EA) were assessed before and after the training intervention. Participants self-reported upper respiratory symptoms during the intervention and episodes of URI were identified retrospectively.Results: Fourteen athletes reported URIs, but there were no differences in incidence, duration or severity between groups. Increased risk of URI was associated with higher s-IgA secretion rates (odds ratio=0.90, 90% CI:0.83-0.97). Lower pre-intervention cortisol and higher EA predicted a 4% increase in URI duration. Participants with higher V̇O2peak reported higher total symptom scores (incidence rate ratio=1.07, 90% CI:1.01-1.13).Conclusions: Although multiple biomarkers were weakly associated with risk of URI, the direction of associations between s-IgA, cortisol, EA and URI risk were inverse to previous observations and physiological rationale. There was a cluster of URIs within the first week of the training intervention, but no samples were collected at this time-point. Future studies should incorporate more frequent sample time-points, especially around the onset of new training regimes, and include athletes with suspected or known nutritional deficiencies.

AB - Purpose: This study explored whether three different HIT prescriptions influence multiple health-related biomarkers and whether biomarker responses to HIT were associated with upper respiratory illness (URI) risk.Methods: Twenty-five male cyclists and triathletes were randomised to three HIT groups and completed twelve HIT sessions over four weeks. Peak oxygen consumption (V̇O2peak) was determined using an incremental cycling protocol, while resting serum biomarkers (cortisol, testosterone, 25(OH)D and ferritin), salivary immunoglobulin-A (s-IgA) and energy availability (EA) were assessed before and after the training intervention. Participants self-reported upper respiratory symptoms during the intervention and episodes of URI were identified retrospectively.Results: Fourteen athletes reported URIs, but there were no differences in incidence, duration or severity between groups. Increased risk of URI was associated with higher s-IgA secretion rates (odds ratio=0.90, 90% CI:0.83-0.97). Lower pre-intervention cortisol and higher EA predicted a 4% increase in URI duration. Participants with higher V̇O2peak reported higher total symptom scores (incidence rate ratio=1.07, 90% CI:1.01-1.13).Conclusions: Although multiple biomarkers were weakly associated with risk of URI, the direction of associations between s-IgA, cortisol, EA and URI risk were inverse to previous observations and physiological rationale. There was a cluster of URIs within the first week of the training intervention, but no samples were collected at this time-point. Future studies should incorporate more frequent sample time-points, especially around the onset of new training regimes, and include athletes with suspected or known nutritional deficiencies.

KW - The Faculty of Science

KW - Endurance athletes

KW - HIT

KW - Immunity

KW - Training load

KW - URT1

U2 - 10.1123/ijspp.2018-0527

DO - 10.1123/ijspp.2018-0527

M3 - Journal article

JO - International Journal of Sports Physiology and Performance

JF - International Journal of Sports Physiology and Performance

SN - 1555-0265

ER -

ID: 217552178