Genotype-phenotype associations in obesity dependent on definition of the obesity phenotype
Research output: Contribution to journal › Journal article › Research › peer-review
In previous studies of associations of variants in the genes UCP2, UCP3, PPARG2, CART, GRL, MC4R, MKKS, SHP, GHRL, and MCHR1 with obesity, we have used a case-control approach with cases defined by a threshold for BMI. In the present study, we assess the association of seven abdominal, peripheral, and overall obesity phenotypes, which were analyzed quantitatively, and thirteen candidate gene polymorphisms in these ten genes in the same cohort.
|Number of pages||8|
|Publication status||Published - 2008|
- Adult, Alleles, Body Fat Distribution, Body Mass Index, Case-Control Studies, Cohort Studies, Denmark, Follow-Up Studies, Genetic Association Studies, Humans, Ion Channels, Logistic Models, Male, Middle Aged, Mitochondrial Proteins, Obesity, Phenotype, Polymorphism, Genetic, Receptors, Cytoplasmic and Nuclear, Receptors, Somatostatin, Waist Circumference