Development and validation of an SPE methodology combined with LC-MS/MS for the determination of four ionophores in aqueous environmental matrices

Research output: Contribution to journalJournal articleResearchpeer-review

Standard

Development and validation of an SPE methodology combined with LC-MS/MS for the determination of four ionophores in aqueous environmental matrices. / Bak, Søren Alex; Hansen, Martin; Krogh, Kristine Andersen; Brandt, Asbjørn; Halling-Sørensen, Bent; Björklund, Erland.

In: International Journal of Environmental Analytical Chemistry, Vol. 93, No. 14, 25.02.2013, p. 1500-1512.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Bak, SA, Hansen, M, Krogh, KA, Brandt, A, Halling-Sørensen, B & Björklund, E 2013, 'Development and validation of an SPE methodology combined with LC-MS/MS for the determination of four ionophores in aqueous environmental matrices', International Journal of Environmental Analytical Chemistry, vol. 93, no. 14, pp. 1500-1512. https://doi.org/10.1080/03067319.2013.763250

APA

Bak, S. A., Hansen, M., Krogh, K. A., Brandt, A., Halling-Sørensen, B., & Björklund, E. (2013). Development and validation of an SPE methodology combined with LC-MS/MS for the determination of four ionophores in aqueous environmental matrices. International Journal of Environmental Analytical Chemistry, 93(14), 1500-1512. https://doi.org/10.1080/03067319.2013.763250

Vancouver

Bak SA, Hansen M, Krogh KA, Brandt A, Halling-Sørensen B, Björklund E. Development and validation of an SPE methodology combined with LC-MS/MS for the determination of four ionophores in aqueous environmental matrices. International Journal of Environmental Analytical Chemistry. 2013 Feb 25;93(14):1500-1512. https://doi.org/10.1080/03067319.2013.763250

Author

Bak, Søren Alex ; Hansen, Martin ; Krogh, Kristine Andersen ; Brandt, Asbjørn ; Halling-Sørensen, Bent ; Björklund, Erland. / Development and validation of an SPE methodology combined with LC-MS/MS for the determination of four ionophores in aqueous environmental matrices. In: International Journal of Environmental Analytical Chemistry. 2013 ; Vol. 93, No. 14. pp. 1500-1512.

Bibtex

@article{fa14e70770af4fc2b6ce9750d3bdedbf,
title = "Development and validation of an SPE methodology combined with LC-MS/MS for the determination of four ionophores in aqueous environmental matrices",
abstract = "A multi-residue analytical methodology has been established for the determination of the four ionophores: lasalocid, monensin, salinomycin and narasin in aqueous environmental matrices, using nigericin as internal standard. The samples were filtrated prior to solid phase extraction. All compounds were measured using liquid chromatography coupled to tandem mass spectrometry applying electro spray ionisation. The absolute recoveries ranged from 92 to 110{\%} (relative standard deviation: 2–14{\%}) for spiked river water. The final method allowed fordetection of ionophores down to a few ng/L in natural water bodies with LOQs for the entire methodology being 40, 49, 67, and 14 ng/L for lasalocid, monensin, salinomycin, and narasin, respectively.",
keywords = "Former Faculty of Pharmaceutical Sciences, Ionophores, pharmaceuticals, anticoccidials, Antibiotics, SPE, LC-MS/MS",
author = "Bak, {S{\o}ren Alex} and Martin Hansen and Krogh, {Kristine Andersen} and Asbj{\o}rn Brandt and Bent Halling-S{\o}rensen and Erland Bj{\"o}rklund",
year = "2013",
month = "2",
day = "25",
doi = "10.1080/03067319.2013.763250",
language = "English",
volume = "93",
pages = "1500--1512",
journal = "International Journal of Environmental Analytical Chemistry",
issn = "0306-7319",
publisher = "Taylor & Francis",
number = "14",

}

RIS

TY - JOUR

T1 - Development and validation of an SPE methodology combined with LC-MS/MS for the determination of four ionophores in aqueous environmental matrices

AU - Bak, Søren Alex

AU - Hansen, Martin

AU - Krogh, Kristine Andersen

AU - Brandt, Asbjørn

AU - Halling-Sørensen, Bent

AU - Björklund, Erland

PY - 2013/2/25

Y1 - 2013/2/25

N2 - A multi-residue analytical methodology has been established for the determination of the four ionophores: lasalocid, monensin, salinomycin and narasin in aqueous environmental matrices, using nigericin as internal standard. The samples were filtrated prior to solid phase extraction. All compounds were measured using liquid chromatography coupled to tandem mass spectrometry applying electro spray ionisation. The absolute recoveries ranged from 92 to 110% (relative standard deviation: 2–14%) for spiked river water. The final method allowed fordetection of ionophores down to a few ng/L in natural water bodies with LOQs for the entire methodology being 40, 49, 67, and 14 ng/L for lasalocid, monensin, salinomycin, and narasin, respectively.

AB - A multi-residue analytical methodology has been established for the determination of the four ionophores: lasalocid, monensin, salinomycin and narasin in aqueous environmental matrices, using nigericin as internal standard. The samples were filtrated prior to solid phase extraction. All compounds were measured using liquid chromatography coupled to tandem mass spectrometry applying electro spray ionisation. The absolute recoveries ranged from 92 to 110% (relative standard deviation: 2–14%) for spiked river water. The final method allowed fordetection of ionophores down to a few ng/L in natural water bodies with LOQs for the entire methodology being 40, 49, 67, and 14 ng/L for lasalocid, monensin, salinomycin, and narasin, respectively.

KW - Former Faculty of Pharmaceutical Sciences

KW - Ionophores

KW - pharmaceuticals

KW - anticoccidials

KW - Antibiotics

KW - SPE

KW - LC-MS/MS

U2 - 10.1080/03067319.2013.763250

DO - 10.1080/03067319.2013.763250

M3 - Journal article

VL - 93

SP - 1500

EP - 1512

JO - International Journal of Environmental Analytical Chemistry

JF - International Journal of Environmental Analytical Chemistry

SN - 0306-7319

IS - 14

ER -

ID: 44795604