Can we prevent obesity-related metabolic diseases by dietary modulation of the gut microbiota?

Research output: Contribution to journalReviewResearchpeer-review

Standard

Can we prevent obesity-related metabolic diseases by dietary modulation of the gut microbiota? / Brahe, Lena Kirchner; Astrup, Arne; Larsen, Lesli Hingstrup.

In: Advances in Nutrition, Vol. 7, No. 1, 2016, p. 90-101.

Research output: Contribution to journalReviewResearchpeer-review

Harvard

Brahe, LK, Astrup, A & Larsen, LH 2016, 'Can we prevent obesity-related metabolic diseases by dietary modulation of the gut microbiota?', Advances in Nutrition, vol. 7, no. 1, pp. 90-101. https://doi.org/10.3945/an.115.010587

APA

Brahe, L. K., Astrup, A., & Larsen, L. H. (2016). Can we prevent obesity-related metabolic diseases by dietary modulation of the gut microbiota? Advances in Nutrition, 7(1), 90-101. https://doi.org/10.3945/an.115.010587

Vancouver

Brahe LK, Astrup A, Larsen LH. Can we prevent obesity-related metabolic diseases by dietary modulation of the gut microbiota? Advances in Nutrition. 2016;7(1):90-101. https://doi.org/10.3945/an.115.010587

Author

Brahe, Lena Kirchner ; Astrup, Arne ; Larsen, Lesli Hingstrup. / Can we prevent obesity-related metabolic diseases by dietary modulation of the gut microbiota?. In: Advances in Nutrition. 2016 ; Vol. 7, No. 1. pp. 90-101.

Bibtex

@article{0b014778caae44cfa8655ade6cdc3c20,
title = "Can we prevent obesity-related metabolic diseases by dietary modulation of the gut microbiota?",
abstract = "Obesity increases the risk of type 2 diabetes, cardiovascular diseases, and certain cancers, which are among the leading causes of death worldwide. Obesity and obesity-related metabolic diseases are characterized by specific alterations in the human gut microbiota. Experimental studies with gut microbiota transplantations in mice and in humans indicate that a specific gut microbiota composition can be the cause and not just the consequence of the obese state and metabolic disease, which suggests a potential for gut microbiota modulation in prevention and treatment of obesity-related metabolic diseases. In addition, dietary intervention studies have suggested that modulation of the gut microbiota can improve metabolic risk markers in humans, but a causal role of the gut microbiota in such studies has not yet been established. Here, we review and discuss the role of the gut microbiota in obesity-related metabolic diseases and the potential of dietary modulation of the gut microbiota in metabolic disease prevention and treatment.",
author = "Brahe, {Lena Kirchner} and Arne Astrup and Larsen, {Lesli Hingstrup}",
note = "CURIS 2016 NEXS 043",
year = "2016",
doi = "10.3945/an.115.010587",
language = "English",
volume = "7",
pages = "90--101",
journal = "Advances in Nutrition",
issn = "2161-8313",
publisher = "American Society for Nutrition",
number = "1",

}

RIS

TY - JOUR

T1 - Can we prevent obesity-related metabolic diseases by dietary modulation of the gut microbiota?

AU - Brahe, Lena Kirchner

AU - Astrup, Arne

AU - Larsen, Lesli Hingstrup

N1 - CURIS 2016 NEXS 043

PY - 2016

Y1 - 2016

N2 - Obesity increases the risk of type 2 diabetes, cardiovascular diseases, and certain cancers, which are among the leading causes of death worldwide. Obesity and obesity-related metabolic diseases are characterized by specific alterations in the human gut microbiota. Experimental studies with gut microbiota transplantations in mice and in humans indicate that a specific gut microbiota composition can be the cause and not just the consequence of the obese state and metabolic disease, which suggests a potential for gut microbiota modulation in prevention and treatment of obesity-related metabolic diseases. In addition, dietary intervention studies have suggested that modulation of the gut microbiota can improve metabolic risk markers in humans, but a causal role of the gut microbiota in such studies has not yet been established. Here, we review and discuss the role of the gut microbiota in obesity-related metabolic diseases and the potential of dietary modulation of the gut microbiota in metabolic disease prevention and treatment.

AB - Obesity increases the risk of type 2 diabetes, cardiovascular diseases, and certain cancers, which are among the leading causes of death worldwide. Obesity and obesity-related metabolic diseases are characterized by specific alterations in the human gut microbiota. Experimental studies with gut microbiota transplantations in mice and in humans indicate that a specific gut microbiota composition can be the cause and not just the consequence of the obese state and metabolic disease, which suggests a potential for gut microbiota modulation in prevention and treatment of obesity-related metabolic diseases. In addition, dietary intervention studies have suggested that modulation of the gut microbiota can improve metabolic risk markers in humans, but a causal role of the gut microbiota in such studies has not yet been established. Here, we review and discuss the role of the gut microbiota in obesity-related metabolic diseases and the potential of dietary modulation of the gut microbiota in metabolic disease prevention and treatment.

U2 - 10.3945/an.115.010587

DO - 10.3945/an.115.010587

M3 - Review

C2 - 26773017

VL - 7

SP - 90

EP - 101

JO - Advances in Nutrition

JF - Advances in Nutrition

SN - 2161-8313

IS - 1

ER -

ID: 154143396