Diet, obesity and health
The research group investigates how diet, individual foods and macronutrients can be related to and used for the prevention and treatment of obesity and its associated diseases such as type-2 diabetes.
Particular focus is on the effects of carbohydrates and proteins (types and quantities), sweeteners and dietary fiber.
This is investigated in shorter and longer intervention studies in relation to appetite control, weight loss, weight loss maintenance, energy metabolism, as well as hormones and signaling substances involved.
Sweeteners and sweetness enhancers: Impact on health, obesity, safety and sustainability
SWEET is a 5-year multidisciplinary EU-project, including 29 partners. The purpose is to develop and review the evidence for the long-term benefits and potential risks associated with dietary sweeteners.
The primary purpose of the project is to investigate the role of sweeteners in weight control, and potentially move viable products to the consumer market.
Prevention of diabetes in Europe and Worldwide
Project period: 2013 to 2018.
PREVIEW is an acronym of PREVention of diabetes through lifestyle Intervention and population studies in Europe and around the World. The project is a large multi-national diabetes prevention project using two different lines of evidence.
The primary goal of PREVIEW was to identify the most efficient lifestyle pattern for the prevention of type-2 diabetes in a population of pre-diabetic overweight or obese individuals.
Designing biofunctional dairy foods: matrix structure of dairy products in relation to lipaemia
Project period: 1 June 2017 to 31 May 2020.
DairyMat is a human intervention study investigating how the structure of dairy products modulates postprandial lipaemia (the lipid content in the blood).
Evidence has emerged that the postprandial response is fundamental for understanding how the diet contributes to development of lifestyle-related diseases such as the metabolic syndrome.
About the project
Structurally different dairy food matrices with identical nutrient composition of fat, protein, carbohydrate, and minerals are hypothesized to affect the postprandial lipemia. The project presents a novel and new interdisciplinary approach, where food structure and texture, in vitro digestibility, in vivo human postprandial response and metabolomics are combined to elucidate the correlation hypothesized.
Four dairy products representing solid to liquid textures, with native or homogenized milk fat globules, and with/without protein network structure are developed. A cross-over postprandial study with 25 participants (or 20 completers) offered these products is performed. Blood samples are analysed for response in among others; triglyceride concentration, lipoproteins, free fatty acids, glucose, insulin, and metabolites.
We expect to gain knowledge of which structures of dairy matrices modulate the lipid uptake, and how these structures can be used strategically to change kinetics of the postprandial fat absorption.
DairyMat is a research project conducted together with researchers from Aarhus University and Arla Foods Amba.
Involved in the project
Professor Anne Raben, University of Copenhagen.
Adjunkt Louise Kjølbæk, University of Copenhagen.
Professor Marianne Hammershøj (project leader), Aarhus University.
Professor Hanne Christine Bertram, Aarhus University.
Assistant Professor Louise Kjølbæk
Fish Intervention Study
Project period: 2013 - 2016.
Obesity is a main underlying factor for development of the metabolic syndrome. Marine oils are well known to protect against diet-induced obesity in rodents and the protein constituent of seafood may be beneficial in weight management.
The hypothesis of this project is that seafood proteins given in the right combination with carbohydrates are superior to meat in promoting increased energy expenditure and satiety.
At NEXS, we perform at 4-way cross-over meal test study comparing cod or salmon vs veal as well as the combination with high or low–glycaemic index carbohydrates.
A total of 48 subjects will be included and each measurement day will include ventilated hood measures, appetite scores and blood sampling.
The study is part of a larger multicentre project with partners mainly based in Norway and Denmark.
Professor Anne Raben
Members of research group
|Anne Marie Raabyemagle||Nutrition Consultant||+4535332486|
|Louise Kjølbæk||Assistant Professor||+4535331462|
|Sabina Stoffer Hjorth Andersen||PhD Fellow||+4535336362|
|Sofie Skov Frost||Biomedical Laboratory Scientist||+4535320255|