The Infant Anthropometry and Body Composition (iABC)

The study is a birth cohort study among 600 newborn children born at term at Jimma University Specialised Hospital in Ethiopia.

 

 

 

Body composition was measured using an air-plethysmography (PeaPod) within the first 48 hours and several times during the first half year of life (iABC-1).

Recruitment took place between 2008-12. Subsequently, children have been followed up at 2, 3, 4-5 and 8-10 years, for anthropometry, body composition (BodPod), child development, markers of cardio-metabolic health, educational outcomes, and kidney size and function.

 

 

The 8-10 year follow-up data are expected to be published in 2022-23.

The study has so far provided data for 4 Ethiopian (incl. 2 ongoing) and 2 Danish PhD-students, and for 14 papers (see publications).

 

 

  1. Abera M, Tesfaye M, Girma T, Hanlon C, Andersen GS, Wells JC, et al. Relation between body composition at birth and child development at 2 years of age: a prospective cohort study among Ethiopian children. Eur J Clin Nutr. 2017;71: 1411–1417. doi:10.1038/ejcn.2017.129
  2. Abera M, Tesfaye M, Admassu B, Hanlon C, Ritz C, Wibaek R, et al. Body composition during early infancy and developmental progression from 1 to 5 years of age: the Infant Anthropometry and Body Composition (iABC) cohort study among Ethiopian children. Br J Nutr. 2018;119: 1263–1273. doi:10.1017/S000711451800082X
  3. Abera M, Tesfaye M, Hanlon C, Admassu B, Girma T, Wells JC, et al. Body Composition during Early Infancy and Mental Health Outcomes at 5 Years of Age: A Prospective Cohort Study of Ethiopian Children. The Journal of Pediatrics. 2018;200: 225–231. doi:10.1016/j.jpeds.2018.04.055
  4. Admassu B, Ritz C, Wells JC, Girma T, Andersen GS, Belachew T, et al. Accretion of Fat-Free Mass Rather Than Fat Mass in Infancy Is Positively Associated with Linear Growth in Childhood. The Journal of Nutrition. 2018;148: 607–615. doi:10.1093/jn/nxy003
  5. Admassu B, Wells JCK, Girma T, Andersen GS, Owino V, Belachew T, et al. Body composition at birth and height at 2 years: a prospective cohort study among children in Jimma, Ethiopia. Pediatr Res. 2017;82: 209–214. doi:10.1038/pr.2017.59
  6. Admassu B, Wells JCK, Girma T, Belachew T, Ritz C, Owino V, et al. Body composition during early infancy and its relation with body composition at 4 years of age in Jimma, an Ethiopian prospective cohort study. Nutr & Diabetes. 2018;8: 46. doi:10.1038/s41387-018-0056-7
  7. Andersen GS, Girma T, Wells JCK, Kæstel P, Michaelsen KF, Friis H. Fat and Fat-Free Mass at Birth: Air Displacement Plethysmography Measurements on 350 Ethiopian Newborns. Pediatr Res. 2011;70: 501–506. doi:10.1203/PDR.0b013e31822d7470
  8. Andersen GS, Girma T, Wells JC, Kæstel P, Leventi M, Hother A-L, et al. Body composition from birth to 6 mo of age in Ethiopian infants: reference data obtained by air-displacement plethysmography. The American Journal of Clinical Nutrition. 2013;98: 885–894. doi:10.3945/ajcn.113.063032
  9. Andersen GS, Wibaek R, Kaestel P, Girma T, Admassu B, Abera M, et al. Body Composition Growth Patterns in Early Infancy: A Latent Class Trajectory Analysis of the Ethiopian iABC Birth Cohort: Body Composition Growth Patterns in Early Infancy. Obesity. 2018;26: 1225–1233. doi:10.1002/oby.22197
  10. Grijalva-Eternod CS, Wells JC, Girma T, Kæstel P, Admassu B, Friis H, et al. Midupper arm circumference and weight-for-length z scores have different associations with body composition: evidence from a cohort of Ethiopian infants. The American Journal of Clinical Nutrition. 2015;102: 593–599. doi:10.3945/ajcn.114.106419
  11. Wibæk R, Kæstel P, Skov SR, Christensen DL, Girma T, Wells JCK, et al. Calibration of bioelectrical impedance analysis for body composition assessment in Ethiopian infants using air-displacement plethysmography. Eur J Clin Nutr. 2015 [cited 16 Jul 2015]. doi:10.1038/ejcn.2015.51
  12. Wibaek R, Girma T, Admassu B, Abera M, Abdissa A, Geto Z, et al. Higher Weight and Weight Gain after 4 Years of Age Rather than Weight at Birth Are Associated with Adiposity, Markers of Glucose Metabolism, and Blood Pressure in 5-Year-Old Ethiopian Children. The Journal of Nutrition. 2019; nxz121. doi:10.1093/jn/nxz121
  13. Wibaek R, Vistisen D, Girma T, Admassu B, Abera M, Abdissa A, et al. Body mass index trajectories in early childhood in relation to cardiometabolic risk profile and body composition at 5 years of age. Am J Clin Nutr. 2019;110: 1175–1185. doi:10.1093/ajcn/nqz170
  14. Wibaek R, Vistisen D, Girma T, Admassu B, Abera M, Abdissa A, et al. Associations of fat mass and fat-free mass accretion in infancy with body composition and cardiometabolic risk markers at 5 years: The Ethiopian iABC birth cohort study. PLOS Medicine. 2019;16: e1002888. doi:10.1371/journal.pmed.1002888

 

 

iABC was initiated in collaboration between Jimma University and University of Copenhagen. Later, researchers from Steno Diabetes Centre Copenhagen, and University College London and London School of Hygiene and Tropical Medicine joined.

 

Involved in the project

Name Title Phone E-mail
Bikila Soboka Megersa PhD Student   E-mail
Henrik Friis Professor +4535333860 E-mail

Funded by

  • Danida
  • University of Copenhagen
  • Novo Nordisk Foundation
  • GSK

Period: 2008 - 2023.

Contact

Mette Frahm Olsen
Associate Professor