Wholegrain intake, growth and metabolic markers in Danish infants and toddlers: a longitudinal study

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Wholegrain intake, growth and metabolic markers in Danish infants and toddlers: a longitudinal study. / Madsen, Marie Terese Barlebo; Biltoft-Jensen, Anja P; Trolle, Ellen; Lauritzen, Lotte; Michaelsen, Kim F.; Damsgaard, Camilla Trab.

I: European Journal of Nutrition, Bind 61, Nr. 7, 2022, s. 3545-3557.

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Harvard

Madsen, MTB, Biltoft-Jensen, AP, Trolle, E, Lauritzen, L, Michaelsen, KF & Damsgaard, CT 2022, 'Wholegrain intake, growth and metabolic markers in Danish infants and toddlers: a longitudinal study', European Journal of Nutrition, bind 61, nr. 7, s. 3545-3557. https://doi.org/10.1007/s00394-022-02902-2

APA

Madsen, M. T. B., Biltoft-Jensen, A. P., Trolle, E., Lauritzen, L., Michaelsen, K. F., & Damsgaard, C. T. (2022). Wholegrain intake, growth and metabolic markers in Danish infants and toddlers: a longitudinal study. European Journal of Nutrition, 61(7), 3545-3557. https://doi.org/10.1007/s00394-022-02902-2

Vancouver

Madsen MTB, Biltoft-Jensen AP, Trolle E, Lauritzen L, Michaelsen KF, Damsgaard CT. Wholegrain intake, growth and metabolic markers in Danish infants and toddlers: a longitudinal study. European Journal of Nutrition. 2022;61(7):3545-3557. https://doi.org/10.1007/s00394-022-02902-2

Author

Madsen, Marie Terese Barlebo ; Biltoft-Jensen, Anja P ; Trolle, Ellen ; Lauritzen, Lotte ; Michaelsen, Kim F. ; Damsgaard, Camilla Trab. / Wholegrain intake, growth and metabolic markers in Danish infants and toddlers: a longitudinal study. I: European Journal of Nutrition. 2022 ; Bind 61, Nr. 7. s. 3545-3557.

Bibtex

@article{321a406f495d4f63a213bd082ed7becd,
title = "Wholegrain intake, growth and metabolic markers in Danish infants and toddlers: a longitudinal study",
abstract = "Purpose: Wholegrain intake is linked to lower risk of lifestyle diseases, but little is known about its role in growth and metabolic health during the first years of life. We characterized wholegrain and dietary fibre intake in 439 Danish children at 9 and 36 months of age and explored associations with height z-scores (HAZ), body mass index z-scores (BMIZ) and metabolic markers.Methods: We used pooled data from two infant cohorts and estimated intakes of total wholegrain, dietary fibre and wholegrain subtypes from 7-day dietary records. Associations with HAZ, BMIZ and non-fasting plasma low-density (LDLC) and high-density-lipoprotein cholesterol, triacylglycerol, insulin and glucose were analysed in mixed models, adjusted for potential confounders.Results: Median (25th, 75th percentile) wholegrain intake was 7.5 (4.9, 10.5) and 6.5 (4.6, 9.0) g/MJ at 9 and 36 months. Neither wholegrain nor dietary fibre intake were associated with HAZ (P ≥ 0.09). At 36 months, wholegrain intake was inversely associated with LDLC (P = 0.05) and directly with glucose (P < 0.001). In secondary analyses, wholegrain rye was inversely associated with glucose at 9 months and insulin at 36 months (both P ≤ 0.03). Oat and wheat wholegrain were directly associated with glucose (both P ≤ 0.01) and wheat with BMIZ (P = 0.02) at 36 months.Conclusion: Danish infants and toddlers have high intakes of wholegrain and dietary fibre, with no indication of compromised growth. In line with studies in adults, wholegrain intake was inversely associated with LDLC. The observed direct association between wholegrain intake and plasma glucose and associations with wholegrain subtypes should be investigated further.",
keywords = "Faculty of Science, Dietary fibre, Young children, Cholesterol, Insulin, Biomarkers, Linear growth",
author = "Madsen, {Marie Terese Barlebo} and Biltoft-Jensen, {Anja P} and Ellen Trolle and Lotte Lauritzen and Michaelsen, {Kim F.} and Damsgaard, {Camilla Trab}",
note = "{\textcopyright} 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany.",
year = "2022",
doi = "10.1007/s00394-022-02902-2",
language = "English",
volume = "61",
pages = "3545--3557",
journal = "European Journal of Nutrition",
issn = "1436-6207",
publisher = "Springer Medizin",
number = "7",

}

RIS

TY - JOUR

T1 - Wholegrain intake, growth and metabolic markers in Danish infants and toddlers: a longitudinal study

AU - Madsen, Marie Terese Barlebo

AU - Biltoft-Jensen, Anja P

AU - Trolle, Ellen

AU - Lauritzen, Lotte

AU - Michaelsen, Kim F.

AU - Damsgaard, Camilla Trab

N1 - © 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany.

PY - 2022

Y1 - 2022

N2 - Purpose: Wholegrain intake is linked to lower risk of lifestyle diseases, but little is known about its role in growth and metabolic health during the first years of life. We characterized wholegrain and dietary fibre intake in 439 Danish children at 9 and 36 months of age and explored associations with height z-scores (HAZ), body mass index z-scores (BMIZ) and metabolic markers.Methods: We used pooled data from two infant cohorts and estimated intakes of total wholegrain, dietary fibre and wholegrain subtypes from 7-day dietary records. Associations with HAZ, BMIZ and non-fasting plasma low-density (LDLC) and high-density-lipoprotein cholesterol, triacylglycerol, insulin and glucose were analysed in mixed models, adjusted for potential confounders.Results: Median (25th, 75th percentile) wholegrain intake was 7.5 (4.9, 10.5) and 6.5 (4.6, 9.0) g/MJ at 9 and 36 months. Neither wholegrain nor dietary fibre intake were associated with HAZ (P ≥ 0.09). At 36 months, wholegrain intake was inversely associated with LDLC (P = 0.05) and directly with glucose (P < 0.001). In secondary analyses, wholegrain rye was inversely associated with glucose at 9 months and insulin at 36 months (both P ≤ 0.03). Oat and wheat wholegrain were directly associated with glucose (both P ≤ 0.01) and wheat with BMIZ (P = 0.02) at 36 months.Conclusion: Danish infants and toddlers have high intakes of wholegrain and dietary fibre, with no indication of compromised growth. In line with studies in adults, wholegrain intake was inversely associated with LDLC. The observed direct association between wholegrain intake and plasma glucose and associations with wholegrain subtypes should be investigated further.

AB - Purpose: Wholegrain intake is linked to lower risk of lifestyle diseases, but little is known about its role in growth and metabolic health during the first years of life. We characterized wholegrain and dietary fibre intake in 439 Danish children at 9 and 36 months of age and explored associations with height z-scores (HAZ), body mass index z-scores (BMIZ) and metabolic markers.Methods: We used pooled data from two infant cohorts and estimated intakes of total wholegrain, dietary fibre and wholegrain subtypes from 7-day dietary records. Associations with HAZ, BMIZ and non-fasting plasma low-density (LDLC) and high-density-lipoprotein cholesterol, triacylglycerol, insulin and glucose were analysed in mixed models, adjusted for potential confounders.Results: Median (25th, 75th percentile) wholegrain intake was 7.5 (4.9, 10.5) and 6.5 (4.6, 9.0) g/MJ at 9 and 36 months. Neither wholegrain nor dietary fibre intake were associated with HAZ (P ≥ 0.09). At 36 months, wholegrain intake was inversely associated with LDLC (P = 0.05) and directly with glucose (P < 0.001). In secondary analyses, wholegrain rye was inversely associated with glucose at 9 months and insulin at 36 months (both P ≤ 0.03). Oat and wheat wholegrain were directly associated with glucose (both P ≤ 0.01) and wheat with BMIZ (P = 0.02) at 36 months.Conclusion: Danish infants and toddlers have high intakes of wholegrain and dietary fibre, with no indication of compromised growth. In line with studies in adults, wholegrain intake was inversely associated with LDLC. The observed direct association between wholegrain intake and plasma glucose and associations with wholegrain subtypes should be investigated further.

KW - Faculty of Science

KW - Dietary fibre

KW - Young children

KW - Cholesterol

KW - Insulin

KW - Biomarkers

KW - Linear growth

U2 - 10.1007/s00394-022-02902-2

DO - 10.1007/s00394-022-02902-2

M3 - Journal article

C2 - 35622136

VL - 61

SP - 3545

EP - 3557

JO - European Journal of Nutrition

JF - European Journal of Nutrition

SN - 1436-6207

IS - 7

ER -

ID: 307729889