Reduced volume but increased training intensity elevates muscle Na+-K+ pump alpha1-subunit and NHE1 expression as well as short-term work capacity in humans

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Standard

Reduced volume but increased training intensity elevates muscle Na+-K+ pump alpha1-subunit and NHE1 expression as well as short-term work capacity in humans. / Iaia, F. Marcello; Thomassen, Martin; Kolding, Helle; Gunnarsson, Thomas Gunnar Petursson; Wendell, Jesper; Rostgaard, Thomas; Nordsborg, Nikolai; Krustrup, Peter; Nybo, Lars; Hellsten, Ylva; Bangsbo, Jens.

I: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, Bind 294, Nr. 3, 2008, s. R966-R974.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Iaia, FM, Thomassen, M, Kolding, H, Gunnarsson, TGP, Wendell, J, Rostgaard, T, Nordsborg, N, Krustrup, P, Nybo, L, Hellsten, Y & Bangsbo, J 2008, 'Reduced volume but increased training intensity elevates muscle Na+-K+ pump alpha1-subunit and NHE1 expression as well as short-term work capacity in humans', American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, bind 294, nr. 3, s. R966-R974. https://doi.org/10.1152/ajpregu.00666.2007

APA

Iaia, F. M., Thomassen, M., Kolding, H., Gunnarsson, T. G. P., Wendell, J., Rostgaard, T., ... Bangsbo, J. (2008). Reduced volume but increased training intensity elevates muscle Na+-K+ pump alpha1-subunit and NHE1 expression as well as short-term work capacity in humans. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, 294(3), R966-R974. https://doi.org/10.1152/ajpregu.00666.2007

Vancouver

Iaia FM, Thomassen M, Kolding H, Gunnarsson TGP, Wendell J, Rostgaard T o.a. Reduced volume but increased training intensity elevates muscle Na+-K+ pump alpha1-subunit and NHE1 expression as well as short-term work capacity in humans. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 2008;294(3):R966-R974. https://doi.org/10.1152/ajpregu.00666.2007

Author

Iaia, F. Marcello ; Thomassen, Martin ; Kolding, Helle ; Gunnarsson, Thomas Gunnar Petursson ; Wendell, Jesper ; Rostgaard, Thomas ; Nordsborg, Nikolai ; Krustrup, Peter ; Nybo, Lars ; Hellsten, Ylva ; Bangsbo, Jens. / Reduced volume but increased training intensity elevates muscle Na+-K+ pump alpha1-subunit and NHE1 expression as well as short-term work capacity in humans. I: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 2008 ; Bind 294, Nr. 3. s. R966-R974.

Bibtex

@article{2a6bb020eea411dcbee902004c4f4f50,
title = "Reduced volume but increased training intensity elevates muscle Na+-K+ pump alpha1-subunit and NHE1 expression as well as short-term work capacity in humans",
abstract = "The present study examined muscle adaptations and alterations in work capacity in endurance-trained runners after a change from endurance to sprint training. Fifteen runners were assigned to either a sprint training (ST, n = 8) or a control (CON, n = 7) group. ST replaced their normal training by 30-s sprint runs three to four times a week, whereas CON continued the endurance training ( approximately 45 km/wk). After the 4-wk sprint period, the expression of the muscle Na(+)-K(+) pump alpha(1)-subunit and Na(+)/H(+)-exchanger isoform 1 was 29 and 30{\%} higher (P < 0.05), respectively. Furthermore, plasma K(+) concentration was reduced (P < 0.05) during repeated intense running. In ST, performance in a 30-s sprint test, Yo-Yo intermittent recovery test, and two supramaximal exhaustive runs was improved (P < 0.05) by 7, 19, 27, and 19{\%}, respectively, after the sprint training period, whereas pulmonary maximum oxygen uptake and 10-k time were unchanged. No changes in CON were observed. The present data suggest a role of the Na(+)-K(+) pump in the control of K(+) homeostasis and in the development of fatigue during repeated high-intensity exercise. Furthermore, performance during intense exercise can be improved and endurance performance maintained even with a reduction in training volume if the intensity of training is very high.",
author = "Iaia, {F. Marcello} and Martin Thomassen and Helle Kolding and Gunnarsson, {Thomas Gunnar Petursson} and Jesper Wendell and Thomas Rostgaard and Nikolai Nordsborg and Peter Krustrup and Lars Nybo and Ylva Hellsten and Jens Bangsbo",
note = "CURIS 2008 5200 003",
year = "2008",
doi = "10.1152/ajpregu.00666.2007",
language = "English",
volume = "294",
pages = "R966--R974",
journal = "American Journal of Physiology: Regulatory, Integrative and Comparative Physiology",
issn = "0363-6119",
publisher = "American Physiological Society",
number = "3",

}

RIS

TY - JOUR

T1 - Reduced volume but increased training intensity elevates muscle Na+-K+ pump alpha1-subunit and NHE1 expression as well as short-term work capacity in humans

AU - Iaia, F. Marcello

AU - Thomassen, Martin

AU - Kolding, Helle

AU - Gunnarsson, Thomas Gunnar Petursson

AU - Wendell, Jesper

AU - Rostgaard, Thomas

AU - Nordsborg, Nikolai

AU - Krustrup, Peter

AU - Nybo, Lars

AU - Hellsten, Ylva

AU - Bangsbo, Jens

N1 - CURIS 2008 5200 003

PY - 2008

Y1 - 2008

N2 - The present study examined muscle adaptations and alterations in work capacity in endurance-trained runners after a change from endurance to sprint training. Fifteen runners were assigned to either a sprint training (ST, n = 8) or a control (CON, n = 7) group. ST replaced their normal training by 30-s sprint runs three to four times a week, whereas CON continued the endurance training ( approximately 45 km/wk). After the 4-wk sprint period, the expression of the muscle Na(+)-K(+) pump alpha(1)-subunit and Na(+)/H(+)-exchanger isoform 1 was 29 and 30% higher (P < 0.05), respectively. Furthermore, plasma K(+) concentration was reduced (P < 0.05) during repeated intense running. In ST, performance in a 30-s sprint test, Yo-Yo intermittent recovery test, and two supramaximal exhaustive runs was improved (P < 0.05) by 7, 19, 27, and 19%, respectively, after the sprint training period, whereas pulmonary maximum oxygen uptake and 10-k time were unchanged. No changes in CON were observed. The present data suggest a role of the Na(+)-K(+) pump in the control of K(+) homeostasis and in the development of fatigue during repeated high-intensity exercise. Furthermore, performance during intense exercise can be improved and endurance performance maintained even with a reduction in training volume if the intensity of training is very high.

AB - The present study examined muscle adaptations and alterations in work capacity in endurance-trained runners after a change from endurance to sprint training. Fifteen runners were assigned to either a sprint training (ST, n = 8) or a control (CON, n = 7) group. ST replaced their normal training by 30-s sprint runs three to four times a week, whereas CON continued the endurance training ( approximately 45 km/wk). After the 4-wk sprint period, the expression of the muscle Na(+)-K(+) pump alpha(1)-subunit and Na(+)/H(+)-exchanger isoform 1 was 29 and 30% higher (P < 0.05), respectively. Furthermore, plasma K(+) concentration was reduced (P < 0.05) during repeated intense running. In ST, performance in a 30-s sprint test, Yo-Yo intermittent recovery test, and two supramaximal exhaustive runs was improved (P < 0.05) by 7, 19, 27, and 19%, respectively, after the sprint training period, whereas pulmonary maximum oxygen uptake and 10-k time were unchanged. No changes in CON were observed. The present data suggest a role of the Na(+)-K(+) pump in the control of K(+) homeostasis and in the development of fatigue during repeated high-intensity exercise. Furthermore, performance during intense exercise can be improved and endurance performance maintained even with a reduction in training volume if the intensity of training is very high.

U2 - 10.1152/ajpregu.00666.2007

DO - 10.1152/ajpregu.00666.2007

M3 - Journal article

C2 - 18094063

VL - 294

SP - R966-R974

JO - American Journal of Physiology: Regulatory, Integrative and Comparative Physiology

JF - American Journal of Physiology: Regulatory, Integrative and Comparative Physiology

SN - 0363-6119

IS - 3

ER -

ID: 3089956