Pretreatment fasting plasma glucose modifies dietary weight loss maintenance success: Results from a stratified RCT

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Standard

Pretreatment fasting plasma glucose modifies dietary weight loss maintenance success : Results from a stratified RCT. / Hjorth, Mads Fiil; Due, Anette; Larsen, Thomas Meinert; Astrup, Arne.

I: Obesity, Bind 25, Nr. 12, 2017, s. 2045-2048.

Publikation: Bidrag til tidsskriftTidsskriftartikelfagfællebedømt

Harvard

Hjorth, MF, Due, A, Larsen, TM & Astrup, A 2017, 'Pretreatment fasting plasma glucose modifies dietary weight loss maintenance success: Results from a stratified RCT', Obesity, bind 25, nr. 12, s. 2045-2048. https://doi.org/10.1002/oby.22004

APA

Hjorth, M. F., Due, A., Larsen, T. M., & Astrup, A. (2017). Pretreatment fasting plasma glucose modifies dietary weight loss maintenance success: Results from a stratified RCT. Obesity, 25(12), 2045-2048. https://doi.org/10.1002/oby.22004

Vancouver

Hjorth MF, Due A, Larsen TM, Astrup A. Pretreatment fasting plasma glucose modifies dietary weight loss maintenance success: Results from a stratified RCT. Obesity. 2017;25(12):2045-2048. https://doi.org/10.1002/oby.22004

Author

Hjorth, Mads Fiil ; Due, Anette ; Larsen, Thomas Meinert ; Astrup, Arne. / Pretreatment fasting plasma glucose modifies dietary weight loss maintenance success : Results from a stratified RCT. I: Obesity. 2017 ; Bind 25, Nr. 12. s. 2045-2048.

Bibtex

@article{7fdbd57232404b48bc84b7921a19d84a,
title = "Pretreatment fasting plasma glucose modifies dietary weight loss maintenance success: Results from a stratified RCT",
abstract = "OBJECTIVE: Levels of fasting plasma glucose (FPG) and fasting insulin (FI) were studied as diet-specific prognostic markers for successful weight loss maintenance in participants with overweight.METHODS: After losing ≥ 8% of body weight, participants received one of three ad libitum diets for 6 months: (1) a moderate-fat diet high in monounsaturated fatty acids (MUFA); (2) a low-fat, high-fiber diet (Nordic Nutrition Recommendations [NNR]); and (3) the Average Danish Diet (ADD). Participants were categorized as having low (< 90 mg/dL) or high (90-105 mg/dL) FPG based on preintervention values. Median FI among those having high FPG was used as a cutoff for FI (FI ≤ 50 pmol/L; FI > 50 pmol/L).RESULTS: Participants with low FPG and randomized to MUFA, NNR, and ADD regained similarly 2.1 to 2.5 kg after 6 months. By contrast, participants with high FPG and randomized to MUFA, NNR, and ADD regained 2.73 kg (95% CI 1.33 to 4.13; P < 0.001), -0.05 kg (95% CI -1.95 to 1.86; P = 0.96), and 4.16 kg (95% CI 2.27 to 6.06; P < 0.001) after 6 months, respectively, resulting in lower weight regain on NNR compared to ADD (-4.21 kg [95% CI -6.83 to -1.59]; P = 0.002) and MUFA (95% CI -2.77 kg [-5.12 to -0.43]; P = 0.020). The addition of FI strengthened these associations.CONCLUSIONS: Slightly elevated pretreatment FPG determined success in dietary weight loss maintenance among overweight patients on ad libitum diets differing in macronutrient and fiber content.",
keywords = "Journal Article",
author = "Hjorth, {Mads Fiil} and Anette Due and Larsen, {Thomas Meinert} and Arne Astrup",
note = "CURIS 2017 NEXS 267",
year = "2017",
doi = "10.1002/oby.22004",
language = "English",
volume = "25",
pages = "2045--2048",
journal = "Obesity",
issn = "1930-7381",
publisher = "Wiley-Blackwell",
number = "12",

}

RIS

TY - JOUR

T1 - Pretreatment fasting plasma glucose modifies dietary weight loss maintenance success

T2 - Results from a stratified RCT

AU - Hjorth, Mads Fiil

AU - Due, Anette

AU - Larsen, Thomas Meinert

AU - Astrup, Arne

N1 - CURIS 2017 NEXS 267

PY - 2017

Y1 - 2017

N2 - OBJECTIVE: Levels of fasting plasma glucose (FPG) and fasting insulin (FI) were studied as diet-specific prognostic markers for successful weight loss maintenance in participants with overweight.METHODS: After losing ≥ 8% of body weight, participants received one of three ad libitum diets for 6 months: (1) a moderate-fat diet high in monounsaturated fatty acids (MUFA); (2) a low-fat, high-fiber diet (Nordic Nutrition Recommendations [NNR]); and (3) the Average Danish Diet (ADD). Participants were categorized as having low (< 90 mg/dL) or high (90-105 mg/dL) FPG based on preintervention values. Median FI among those having high FPG was used as a cutoff for FI (FI ≤ 50 pmol/L; FI > 50 pmol/L).RESULTS: Participants with low FPG and randomized to MUFA, NNR, and ADD regained similarly 2.1 to 2.5 kg after 6 months. By contrast, participants with high FPG and randomized to MUFA, NNR, and ADD regained 2.73 kg (95% CI 1.33 to 4.13; P < 0.001), -0.05 kg (95% CI -1.95 to 1.86; P = 0.96), and 4.16 kg (95% CI 2.27 to 6.06; P < 0.001) after 6 months, respectively, resulting in lower weight regain on NNR compared to ADD (-4.21 kg [95% CI -6.83 to -1.59]; P = 0.002) and MUFA (95% CI -2.77 kg [-5.12 to -0.43]; P = 0.020). The addition of FI strengthened these associations.CONCLUSIONS: Slightly elevated pretreatment FPG determined success in dietary weight loss maintenance among overweight patients on ad libitum diets differing in macronutrient and fiber content.

AB - OBJECTIVE: Levels of fasting plasma glucose (FPG) and fasting insulin (FI) were studied as diet-specific prognostic markers for successful weight loss maintenance in participants with overweight.METHODS: After losing ≥ 8% of body weight, participants received one of three ad libitum diets for 6 months: (1) a moderate-fat diet high in monounsaturated fatty acids (MUFA); (2) a low-fat, high-fiber diet (Nordic Nutrition Recommendations [NNR]); and (3) the Average Danish Diet (ADD). Participants were categorized as having low (< 90 mg/dL) or high (90-105 mg/dL) FPG based on preintervention values. Median FI among those having high FPG was used as a cutoff for FI (FI ≤ 50 pmol/L; FI > 50 pmol/L).RESULTS: Participants with low FPG and randomized to MUFA, NNR, and ADD regained similarly 2.1 to 2.5 kg after 6 months. By contrast, participants with high FPG and randomized to MUFA, NNR, and ADD regained 2.73 kg (95% CI 1.33 to 4.13; P < 0.001), -0.05 kg (95% CI -1.95 to 1.86; P = 0.96), and 4.16 kg (95% CI 2.27 to 6.06; P < 0.001) after 6 months, respectively, resulting in lower weight regain on NNR compared to ADD (-4.21 kg [95% CI -6.83 to -1.59]; P = 0.002) and MUFA (95% CI -2.77 kg [-5.12 to -0.43]; P = 0.020). The addition of FI strengthened these associations.CONCLUSIONS: Slightly elevated pretreatment FPG determined success in dietary weight loss maintenance among overweight patients on ad libitum diets differing in macronutrient and fiber content.

KW - Journal Article

U2 - 10.1002/oby.22004

DO - 10.1002/oby.22004

M3 - Journal article

C2 - 28985039

VL - 25

SP - 2045

EP - 2048

JO - Obesity

JF - Obesity

SN - 1930-7381

IS - 12

ER -

ID: 184390367