TY - JOUR

T1 - Lymphopenia in heavy drinkers - reversibility and relation to the duration of drinking episodes

AU - Trannesen, Hanne

AU - Andersen, Jens Rikardt

AU - Pedersen, Anne E

AU - Kaiser, Anna H

N1 - (Ekstern)

PY - 1990

Y1 - 1990

N2 - Seventyfour addictive alcoholic subjects were investigated shortly after a period of excessive drinking and were compared with 18 alcoholic subjects who had not been drinking for at least six months. No difference was observed in total white cell count or number of circulating granulocytes. Lymphocyte count was significantly lower in alcoholics whose last alcoholic bout had been three months or more, but after 30 days of abstinence the difference had disappeared. The depressed lymphocyte count did not correlate with other components of the drinking pattern. These results show that lymphopenia in alcoholics is a time-dependent and reversible event.

AB - Seventyfour addictive alcoholic subjects were investigated shortly after a period of excessive drinking and were compared with 18 alcoholic subjects who had not been drinking for at least six months. No difference was observed in total white cell count or number of circulating granulocytes. Lymphocyte count was significantly lower in alcoholics whose last alcoholic bout had been three months or more, but after 30 days of abstinence the difference had disappeared. The depressed lymphocyte count did not correlate with other components of the drinking pattern. These results show that lymphopenia in alcoholics is a time-dependent and reversible event.

KW - Alcoholism

KW - Drinking patterns

KW - Leucocytes

KW - Lymphocytes

UR - http://www.scopus.com/inward/record.url?scp=0025186323&partnerID=8YFLogxK

U2 - 10.3109/07853899009148931

DO - 10.3109/07853899009148931

M3 - Journal article

C2 - 2248759

AN - SCOPUS:0025186323

VL - 22

SP - 229

EP - 231

JO - Medical Biology

JF - Medical Biology

SN - 0785-3890

IS - 4

ER -