GLP-1 increases microvascular recruitment but not glucose uptake in human and rat skeletal muscle

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Standard

GLP-1 increases microvascular recruitment but not glucose uptake in human and rat skeletal muscle. / Sjøberg, Kim Anker; Holst, Jens Juul; Rattigan, Stephen; Richter, Erik A.; Kiens, Bente.

I: American Journal of Physiology: Endocrinology and Metabolism, Bind 306, Nr. 4, 2014, s. E355-E362.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Sjøberg, KA, Holst, JJ, Rattigan, S, Richter, EA & Kiens, B 2014, 'GLP-1 increases microvascular recruitment but not glucose uptake in human and rat skeletal muscle', American Journal of Physiology: Endocrinology and Metabolism, bind 306, nr. 4, s. E355-E362. https://doi.org/10.1152/ajpendo.00283.2013

APA

Sjøberg, K. A., Holst, J. J., Rattigan, S., Richter, E. A., & Kiens, B. (2014). GLP-1 increases microvascular recruitment but not glucose uptake in human and rat skeletal muscle. American Journal of Physiology: Endocrinology and Metabolism, 306(4), E355-E362. https://doi.org/10.1152/ajpendo.00283.2013

Vancouver

Sjøberg KA, Holst JJ, Rattigan S, Richter EA, Kiens B. GLP-1 increases microvascular recruitment but not glucose uptake in human and rat skeletal muscle. American Journal of Physiology: Endocrinology and Metabolism. 2014;306(4):E355-E362. https://doi.org/10.1152/ajpendo.00283.2013

Author

Sjøberg, Kim Anker ; Holst, Jens Juul ; Rattigan, Stephen ; Richter, Erik A. ; Kiens, Bente. / GLP-1 increases microvascular recruitment but not glucose uptake in human and rat skeletal muscle. I: American Journal of Physiology: Endocrinology and Metabolism. 2014 ; Bind 306, Nr. 4. s. E355-E362.

Bibtex

@article{800d68a128974d7799b0e6143aea8aaa,
title = "GLP-1 increases microvascular recruitment but not glucose uptake in human and rat skeletal muscle",
abstract = "The insulinotropic gut hormone, glucagon-like-peptide-1 (GLP-1) has been proposed to have effects on vascular function and glucose disposal. However, whether GLP-1 is able to increase microvascular recruitment (MVR) in humans has not been investigated. GLP-1 was infused in the femoral artery in overnight fasted healthy young men. Microvascular recruitment was measured with real time contrast-enhanced ultrasound and leg glucose uptake by the leg balance technique with and without inhibition of the insulinotropic response of GLP-1 by co-infusion of octreotide. As a positive control, MVR and leg glucose uptake were measured during a hyperinsulinemic euglycemic clamp. Infusion of GLP-1 caused a rapid increase (P",
author = "Sj{\o}berg, {Kim Anker} and Holst, {Jens Juul} and Stephen Rattigan and Richter, {Erik A.} and Bente Kiens",
note = "CURIS 2014 NEXS 054",
year = "2014",
doi = "10.1152/ajpendo.00283.2013",
language = "English",
volume = "306",
pages = "E355--E362",
journal = "American Journal of Physiology - Endocrinology and Metabolism",
issn = "0193-1849",
publisher = "American Physiological Society",
number = "4",

}

RIS

TY - JOUR

T1 - GLP-1 increases microvascular recruitment but not glucose uptake in human and rat skeletal muscle

AU - Sjøberg, Kim Anker

AU - Holst, Jens Juul

AU - Rattigan, Stephen

AU - Richter, Erik A.

AU - Kiens, Bente

N1 - CURIS 2014 NEXS 054

PY - 2014

Y1 - 2014

N2 - The insulinotropic gut hormone, glucagon-like-peptide-1 (GLP-1) has been proposed to have effects on vascular function and glucose disposal. However, whether GLP-1 is able to increase microvascular recruitment (MVR) in humans has not been investigated. GLP-1 was infused in the femoral artery in overnight fasted healthy young men. Microvascular recruitment was measured with real time contrast-enhanced ultrasound and leg glucose uptake by the leg balance technique with and without inhibition of the insulinotropic response of GLP-1 by co-infusion of octreotide. As a positive control, MVR and leg glucose uptake were measured during a hyperinsulinemic euglycemic clamp. Infusion of GLP-1 caused a rapid increase (P

AB - The insulinotropic gut hormone, glucagon-like-peptide-1 (GLP-1) has been proposed to have effects on vascular function and glucose disposal. However, whether GLP-1 is able to increase microvascular recruitment (MVR) in humans has not been investigated. GLP-1 was infused in the femoral artery in overnight fasted healthy young men. Microvascular recruitment was measured with real time contrast-enhanced ultrasound and leg glucose uptake by the leg balance technique with and without inhibition of the insulinotropic response of GLP-1 by co-infusion of octreotide. As a positive control, MVR and leg glucose uptake were measured during a hyperinsulinemic euglycemic clamp. Infusion of GLP-1 caused a rapid increase (P

U2 - 10.1152/ajpendo.00283.2013

DO - 10.1152/ajpendo.00283.2013

M3 - Journal article

C2 - 24302010

VL - 306

SP - E355-E362

JO - American Journal of Physiology - Endocrinology and Metabolism

JF - American Journal of Physiology - Endocrinology and Metabolism

SN - 0193-1849

IS - 4

ER -

ID: 92062721