Effect of 2-wk intensified training and inactivity on muscle Na+/K+ pump expression, phospholemman (FXYD1) phosphorylation and performance in soccer players

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Effect of 2-wk intensified training and inactivity on muscle Na+/K+ pump expression, phospholemman (FXYD1) phosphorylation and performance in soccer players. / Thomassen, Martin; Christensen, Peter Møller; Gunnarsson, Thomas Gunnar Petursson; Nybo, Lars; Bangsbo, Jens.

I: Journal of Applied Physiology, Bind 108, Nr. 4, 2010, s. 898-905.

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

Harvard

Thomassen, M, Christensen, PM, Gunnarsson, TGP, Nybo, L & Bangsbo, J 2010, 'Effect of 2-wk intensified training and inactivity on muscle Na+/K+ pump expression, phospholemman (FXYD1) phosphorylation and performance in soccer players', Journal of Applied Physiology, bind 108, nr. 4, s. 898-905. https://doi.org/10.1152/japplphysiol.01015.2009

APA

Thomassen, M., Christensen, P. M., Gunnarsson, T. G. P., Nybo, L., & Bangsbo, J. (2010). Effect of 2-wk intensified training and inactivity on muscle Na+/K+ pump expression, phospholemman (FXYD1) phosphorylation and performance in soccer players. Journal of Applied Physiology, 108(4), 898-905. https://doi.org/10.1152/japplphysiol.01015.2009

Vancouver

Thomassen M, Christensen PM, Gunnarsson TGP, Nybo L, Bangsbo J. Effect of 2-wk intensified training and inactivity on muscle Na+/K+ pump expression, phospholemman (FXYD1) phosphorylation and performance in soccer players. Journal of Applied Physiology. 2010;108(4):898-905. https://doi.org/10.1152/japplphysiol.01015.2009

Author

Thomassen, Martin ; Christensen, Peter Møller ; Gunnarsson, Thomas Gunnar Petursson ; Nybo, Lars ; Bangsbo, Jens. / Effect of 2-wk intensified training and inactivity on muscle Na+/K+ pump expression, phospholemman (FXYD1) phosphorylation and performance in soccer players. I: Journal of Applied Physiology. 2010 ; Bind 108, Nr. 4. s. 898-905.

Bibtex

@article{430c4eb0513911df928f000ea68e967b,
title = "Effect of 2-wk intensified training and inactivity on muscle Na+/K+ pump expression, phospholemman (FXYD1) phosphorylation and performance in soccer players",
abstract = "The present study examined muscle adaptations and alterations in performance of highly trained soccer players with intensified training or training cessation. Eighteen elite soccer players were for a 2-wk period assigned to either a group which performed high intensity training with a reduction in the amount of training (HI, n=7) or an inactivity group without training (IN, n=11). HI improved (P<0.05) performance of the fourth, sixth and tenth sprint in a repeated 20-m sprint test (RST) and IN reduced (P<0.05) performance in the fifth to the tenth sprint after the 2-wk intervention period. In addition, the Yo-Yo IR2 test performance of IN was lowered from 845+/-48 to 654+/-30 m. In HI the protein expression of the Na(+)/K(+) pump alpha2 isoform was 15{\%} higher (P<0.05) after the intervention period, whereas no changes were observed in alpha1 and beta1 isoform expression. In IN, Na(+)/K(+) pump expression was not changed. In HI, the FXYD1ser68/FXYD1 ratio was 27{\%} higher (P<0.01) after the intervention period, and in IN the AB_FXYD1ser68 signal was 18{\%} lower (P<0.05) after inactivity. The change in FXYD1ser68/FXYD1 ratio was correlated (r(2)=0.35; P<0.05) with change in performance in RST. The present data suggest that short-term intensified training even for trained soccer players can increase muscle Na(+)/K(+) pump alpha2 isoform expression and that cessation of training for two weeks does not affect the expression of Na(+)/K(+) pump isoforms. Resting phosphorylation status of the Na(+)/K(+) pump is changed by training and inactivity and may play a role for performance during repeated intense exercise. Key words: Fatigue, Training cessation, Performance, MCT1.",
author = "Martin Thomassen and Christensen, {Peter M{\o}ller} and Gunnarsson, {Thomas Gunnar Petursson} and Lars Nybo and Jens Bangsbo",
note = "CURIS 2010 5200 053",
year = "2010",
doi = "10.1152/japplphysiol.01015.2009",
language = "English",
volume = "108",
pages = "898--905",
journal = "Journal of Applied Physiology",
issn = "8750-7587",
publisher = "American Physiological Society",
number = "4",

}

RIS

TY - JOUR

T1 - Effect of 2-wk intensified training and inactivity on muscle Na+/K+ pump expression, phospholemman (FXYD1) phosphorylation and performance in soccer players

AU - Thomassen, Martin

AU - Christensen, Peter Møller

AU - Gunnarsson, Thomas Gunnar Petursson

AU - Nybo, Lars

AU - Bangsbo, Jens

N1 - CURIS 2010 5200 053

PY - 2010

Y1 - 2010

N2 - The present study examined muscle adaptations and alterations in performance of highly trained soccer players with intensified training or training cessation. Eighteen elite soccer players were for a 2-wk period assigned to either a group which performed high intensity training with a reduction in the amount of training (HI, n=7) or an inactivity group without training (IN, n=11). HI improved (P<0.05) performance of the fourth, sixth and tenth sprint in a repeated 20-m sprint test (RST) and IN reduced (P<0.05) performance in the fifth to the tenth sprint after the 2-wk intervention period. In addition, the Yo-Yo IR2 test performance of IN was lowered from 845+/-48 to 654+/-30 m. In HI the protein expression of the Na(+)/K(+) pump alpha2 isoform was 15% higher (P<0.05) after the intervention period, whereas no changes were observed in alpha1 and beta1 isoform expression. In IN, Na(+)/K(+) pump expression was not changed. In HI, the FXYD1ser68/FXYD1 ratio was 27% higher (P<0.01) after the intervention period, and in IN the AB_FXYD1ser68 signal was 18% lower (P<0.05) after inactivity. The change in FXYD1ser68/FXYD1 ratio was correlated (r(2)=0.35; P<0.05) with change in performance in RST. The present data suggest that short-term intensified training even for trained soccer players can increase muscle Na(+)/K(+) pump alpha2 isoform expression and that cessation of training for two weeks does not affect the expression of Na(+)/K(+) pump isoforms. Resting phosphorylation status of the Na(+)/K(+) pump is changed by training and inactivity and may play a role for performance during repeated intense exercise. Key words: Fatigue, Training cessation, Performance, MCT1.

AB - The present study examined muscle adaptations and alterations in performance of highly trained soccer players with intensified training or training cessation. Eighteen elite soccer players were for a 2-wk period assigned to either a group which performed high intensity training with a reduction in the amount of training (HI, n=7) or an inactivity group without training (IN, n=11). HI improved (P<0.05) performance of the fourth, sixth and tenth sprint in a repeated 20-m sprint test (RST) and IN reduced (P<0.05) performance in the fifth to the tenth sprint after the 2-wk intervention period. In addition, the Yo-Yo IR2 test performance of IN was lowered from 845+/-48 to 654+/-30 m. In HI the protein expression of the Na(+)/K(+) pump alpha2 isoform was 15% higher (P<0.05) after the intervention period, whereas no changes were observed in alpha1 and beta1 isoform expression. In IN, Na(+)/K(+) pump expression was not changed. In HI, the FXYD1ser68/FXYD1 ratio was 27% higher (P<0.01) after the intervention period, and in IN the AB_FXYD1ser68 signal was 18% lower (P<0.05) after inactivity. The change in FXYD1ser68/FXYD1 ratio was correlated (r(2)=0.35; P<0.05) with change in performance in RST. The present data suggest that short-term intensified training even for trained soccer players can increase muscle Na(+)/K(+) pump alpha2 isoform expression and that cessation of training for two weeks does not affect the expression of Na(+)/K(+) pump isoforms. Resting phosphorylation status of the Na(+)/K(+) pump is changed by training and inactivity and may play a role for performance during repeated intense exercise. Key words: Fatigue, Training cessation, Performance, MCT1.

U2 - 10.1152/japplphysiol.01015.2009

DO - 10.1152/japplphysiol.01015.2009

M3 - Journal article

C2 - 20133439

VL - 108

SP - 898

EP - 905

JO - Journal of Applied Physiology

JF - Journal of Applied Physiology

SN - 8750-7587

IS - 4

ER -

ID: 19428093