Decomposition of wheat bran and ispaghula husk in the stomach and the small intestine of healthy men
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Decomposition of wheat bran and ispaghula husk in the stomach and the small intestine of healthy men. / Andersen, Jens Rikardt; Bukhave, Klaus; Hojgaard, Liselotte; Rasmussen, Henrik Sandvad; Hermansen, N; Worning, Helge; Krag, Einar.
I: Journal of Nutrition, Bind 118, Nr. 3, 1988, s. 326-331.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Decomposition of wheat bran and ispaghula husk in the stomach and the small intestine of healthy men
AU - Andersen, Jens Rikardt
AU - Bukhave, Klaus
AU - Hojgaard, Liselotte
AU - Rasmussen, Henrik Sandvad
AU - Hermansen, N
AU - Worning, Helge
AU - Krag, Einar
N1 - (Ekstern)
PY - 1988
Y1 - 1988
N2 - Decomposition of dietary fibers in the stomach and small bowel was studied in 13 healthy male volunteers. Liquid control meals were compared with test meals, which in addition contained a source of fiber (wheat bran or ispaghula husk) in random order. Aspirations were collected from the stomach, the proximal jejunum, the mid gut and the terminal ileum. Radiolabeled polyethylene glycol-4000 was used as nonabsorbable water-phase marker, and the formation of free arabinose was used to quantify the hydrolysis of dietary fibers. Ingested fibers, aspirates and urine specimens were analyzed for monosaccharides, either free or fiber-bound, by gas-liquid chromatography. Both types of fiber were hydrolyzed in the stomach, but not in the small bowel. Of ispaghula husk, 1-6% was hydrolyzed, as was 5-8% of wheat bran. Intestinal absorption of free arabinose was 85-93%, but excretion of arabinose in the urine was not greater than after control meals. For further evaluation of gastric hydrolysis six additional healthy male volunteers were studied by serial aspirations from the antral part of the stomach. Hydrolysis was instantaneous for both fibers, and was significantly more pronounced for wheat bran than for ispaghula husk.
AB - Decomposition of dietary fibers in the stomach and small bowel was studied in 13 healthy male volunteers. Liquid control meals were compared with test meals, which in addition contained a source of fiber (wheat bran or ispaghula husk) in random order. Aspirations were collected from the stomach, the proximal jejunum, the mid gut and the terminal ileum. Radiolabeled polyethylene glycol-4000 was used as nonabsorbable water-phase marker, and the formation of free arabinose was used to quantify the hydrolysis of dietary fibers. Ingested fibers, aspirates and urine specimens were analyzed for monosaccharides, either free or fiber-bound, by gas-liquid chromatography. Both types of fiber were hydrolyzed in the stomach, but not in the small bowel. Of ispaghula husk, 1-6% was hydrolyzed, as was 5-8% of wheat bran. Intestinal absorption of free arabinose was 85-93%, but excretion of arabinose in the urine was not greater than after control meals. For further evaluation of gastric hydrolysis six additional healthy male volunteers were studied by serial aspirations from the antral part of the stomach. Hydrolysis was instantaneous for both fibers, and was significantly more pronounced for wheat bran than for ispaghula husk.
KW - Faculty of Science
KW - Arabinose
KW - Dietary fiber
KW - Metabolism
KW - Psyllium
KW - Wheat
UR - http://www.scopus.com/inward/record.url?scp=0023874284&partnerID=8YFLogxK
U2 - 10.1093/jn/118.3.326
DO - 10.1093/jn/118.3.326
M3 - Journal article
C2 - 2832568
AN - SCOPUS:0023874284
VL - 118
SP - 326
EP - 331
JO - Journal of Nutrition
JF - Journal of Nutrition
SN - 0022-3166
IS - 3
ER -
ID: 251991454