Cross-sectional associations of objectively measured physical activity with brain-derived neurotrophic factor in adolescents
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Dokumenter
- Andersen_Phys_Behav_2017_accepted
Accepteret manuskript, 137 KB, PDF-dokument
OBJECTIVE: The purpose of this study was to examine the associations between objectively measured physical activity and serum brain-derived neurotrophic factor (BDNF) in adolescents.
METHODS: Cross-sectional analyses were performed using data from 415 adolescents who participated in the 2015 follow-up of the Childhood Health Activity and Motor Performance School Study Denmark (the CHAMPS-study DK). Physical activity was objectively measured by accelerometry monitors. Serum BDNF levels were analyzed using the Enzyme-linked immunosorbent assay (ELISA). Anthropometrics and pubertal status were measured using standardized procedures.
RESULTS: With adjustment for age, pubertal status and body mass index, mean physical activity (counts per minute) was negatively associated with serum BDNF in boys (P=0.013). Similarly, moderate-to-vigorous physical activity (MVPA) was negatively associated with serum BDNF in boys (P=0.035). In girls, mean physical activity and MVPA were not associated with serum BDNF. Without adjustment for wear time, sedentary time was not associated with serum BDNF in either sex.
CONCLUSION: These findings indicate that higher physical activity is associated with lower serum BDNF in boys, but not in girls.
Originalsprog | Engelsk |
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Tidsskrift | Physiology & Behavior |
Vol/bind | 171 |
Sider (fra-til) | 87-91 |
Antal sider | 5 |
ISSN | 0031-9384 |
DOI | |
Status | Udgivet - 15 mar. 2017 |
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ID: 193974811