Scientific methods – University of Copenhagen

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Obesity Research > Scientific methods

Scientific methods

We work primarily with dietary intervention studies, where a group of participants complete one or more treatments over a short or long study period. The participants are monitored before, during and after the intervention periods

The Department has a wide range of facilities, including respiration chambers and ventilated hood systems for measurement of energy expenditure, DEXA scanners for measurement of body composition, a fully equipped research kitchen, accelerometers to assess physical activity and sleep, dieticians for diet and exercise instructions, laboratories where various samples (blood, fat and muscle biopsies, urine, saliva and faeces) are collected and analysed for hormones, genetic makers,  and different measures/makers related to nutritional  status, metabolic disorders and diseases (e.g. metabolic syndrome, type II diabetes, cardiovascular diseases and cancer). Furthermore, we collaborate with other research institutions to do fMRI, measure maximal oxygen uptake, and analyse gut microbiota. These resources allow us to make very detailed phenotypic characterization of the study participants.

Our studies are carried out in accordance with the study protocol, the current version of the Declaration of Helsinki (64 WMA-General Assembly, Fortaleza, Brazil, October 2013), and the ICH-GCP, International Conference on Harmonization E6 Good Clinical Practice, to the extent that this is possible and relevant. In addition, all national laws and regulations of the local ethical committee regarding human research will be strictly enforced.