Ansatte – Københavns Universitet

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Lotte Lauritzen

Lotte Lauritzen

Lektor

Education:
1991: M.Sc. (Cand.scient.) in Biology (Molecular Physiology) from University of Copenhagen
1995: Ph.D. (Lic.scient.) in Cellular Physiology from University of Copenhagen

Employment:

1991: Research Assistent, August Krogh Institute, University of Copenhagen (KU-NAT)
1992-1994: Ph.D.student, Dept. of Pharmacology, Royal Danish School of Pharmacy (KU-FARMA)
1995: Ammenuensis, Dept. of Pharmacology, Danish Pharmaceutical University (KU-FARMA)
1995-1997: Post.Doc., Dept. of Pharmacol., Danish Pharmaceutical University (KU-FARMA)
1997-2002: Assistant Professor, Dept. of Human Nutrition, Royal Veterinary & Agricultural University (KU-LIFE)
2002- : Associate Professor, Dept. of Human Nutr., University of Copenhagen (KU-LIFE)
Maternity leave 27.9.93-01.3.94, 17.4.97-21.9.97, & 24.2.02-01.9.02.

Research areas:

Possible effects of polyunsaturated fatty acids (PUFA), especially long-chain n-3 PUFA in relation to cardiovascular risk markers, metabolic syndrome, immune function, gut microbiota, growth and development. Current new interests are diet-gene-interactions and interactions between intake of PUFA and other nutrients.
Has broad experience in many areas of lipid research – nutrition, cellular functions and signal transduction. Has performed in vitro studies, animal experiments and human intervention studies with lactating mothers, infants and adults.

Teaching experience:

Has over the years been involved in teaching in biochemistry, cell toxicology, signal transduction, essential fatty acid biology, infant nutrition, and evaluation of scientific evidence. Teaching forms has included lectures, practical hand-on- and theoretical courses and counselling in relation to various types of trainee research projects and has been performed at bachelor, master as well as Ph.D. level in relation to different educations within the natural sciences and health.
Teaching responsibilities also include coordination of master courses currently in “Evidence, Diet & Health”. Is furthermore a member of the education board for the nutrition educations at KU-LIFE and for the Bachelor education in Nutrition and Health at University College Metropol. Is certified to teach in English and to supervise Assistent professors at the department. Has so far been supervisor for 10 bachelor, 36 master and 9 Ph.D. students and official opponent at 6 Ph.D.defences (in Denmark and abroard).

Achievements:

Main or co-contractor of four (>2 mio DKK) grants from national research counsels and member of the upcoming LIFE ELITE research group on ”Early LIFE Nutrition” (2010-).
Author of 44 peer-reviewed original research papers, 5 reviews, 2 letters and 1 editorial in international scientific journals, and 7 book contributions (H-index=15 and total citations 1036 (Web of Science Sept. 2011)).
Editorial Board for Maternal & Child Nutrition (2010-), reviewer for a number of international scientific journals and a couple of research agencies.
Organizer of research seminars and scientific meetings at the department, and a workshop on "PUFA and their effects on membrane function and ion channels" (Novo Nordisk A/S, 27.11.2003).
Member of The American Society for Nutrition (2011-), The International Society for the Study of Fatty Acids and Lipids (ISSFAL) (1999-), Danish Nutrition Society (1998-, from 2010 member of the board) and Danish Biochemical Society (1993-).
Participant at some 60 scientific congresses and meetings and co-author on a number of abstracts.

Theses:

L.Lauritzen : Fiskeoliediæts indflydelse på fedtsyresammensætning og cellulære reguleringsmekanismer i Ehrlich ascites tumorceller. Specialerapport, Københavns Universitet, 1991. Supervisors: Ph.D E.K. Hoffmann & Dr. Sc. H.S. Hansen (in Danish).
L.Lauritzen : Fosfolipase D i Leydigceller - betydning i signaltransduktion. Licentiatrapport, Københavns Universitet, 1995. Supervisors: Dr. Sc. H.S. Hansen, evaluated by Ph.D. E.K. Hoffmann & Dr. Med. S. Gammelgaard (in Danish).

Scientific publications in peer reviewed journals 2001-2011 (corresponding author):

Scientific publications in peer reviewed journals 2001-2011 (*corresponding author):
A.D.Andersen, L.Mølbak, T.Thyman, K.F.Michaelsen, & L.Lauritzen*: Dietary long-chain n-3 PUFA, gut microbiota and fat mass in early postnatal piglet development - exploring a potential interplay. PLEFA (In press)
L.Lauritzen*, L.B.S.Harsløf, L.I.Hellgren, M.H.Pedersen, C.Mølgaard, & K.F.Michaelsen: Fish intake, erythrocyte n-3 fatty acid status and metabolic health in Danish adolescent girls and boys. Br. J. Nutr. (In press)
M.H.Pedersen, L.Lauritzen, & L.I.Hellgren: Fish oil combined with short chain fatty acids synergistically prevent tissue accumulation of non-esterified fatty acids during weight loss in obese mice. Br. J. Nutr. (In press)
M.S.Vedtofte, M.U.Jakobsen, L.Lauritzen, & B.L.Heitmann: Dietary ?-linolenic acid, linoleic acid and n-3 long-chain polyunsaturated fatty acid and risk of coronary heart disease. Am. J. Clin. Nutr. 94: 1097-1103; 2011
L.Lauritzen*, T.M.R.Kjær, T.Porsgaard, M.B.Fruekilde, H.Mu, & H.Frøkiær: Maternal intake of fish oil but not of linseed oil reduces the antibody response in neonatal mice. Lipids 46: 171-178, 2011
C.Cheatham, A.S.Nehammer, M.Asserhøj, K.F.Michaelsen, & L.Lauritzen*: Fish oil supplementation during lactation: Effects on cognition and behavior at 7 years of age. Lipids 46: 637-645, 2011
M.H.Pedersen, C.Mølgaard, L.I.Hellgren, J.Matthiessen, J.Juul Holst & L.Lauritzen*: Effect of dietary fish oil on lipid oxidation, body composition, and markers of inflammation in slightly overweight teenage boys. J. Nutr. Metab. Article ID 348368, 6 pages, 2011
A.D.Andersen, L.Mølbak, K.F.Michaelsen, & L.Lauritzen*: Molecular Fingerprints of the Human Fecal Microbiota From 9 to 18 Months Old and the Effect of Fish Oil Supplementation. J. Pediatr. Gastroenterol. Nutr. 53: 303-309, 2011
A.D.Andersen, K.F.Michaelsen, L.I.Hellgren, E.Trolle, & L.Lauritzen*: A randomized controlled intervention with fish oil versus sunflower oil from 9 to 18 months of age - exploring changes in growth and skinfold thicknesses. Ped. Res. 70: 368-374, 2011
K.F.Michaelsen, A.Larnkjær, L.Lauritzen, & C.Mølgaard: Science base of complementary feeding practice in infancy. Curr. Oppin. Clin. Nutr. Metab. Care 13: 277-83, 2010
L.Lauritzen* & S.E.Carlson: Maternal fatty acid status during pregnancy and lactation and relation to newborn and infant status. Maternal Child. Nutr. 7: 41-58, 2011
K.F.Michaelsen, A. Perez-Exposito, M.Nurhasan, K.Dewey, L.Lauritzen, & N.Roos: Food sources and intake of n-6 and n-3 fatty acids in low-income countries with emphasis on infants, young children (6-24 mo), and pregnant and lactating women. Maternal Child. Nutr. 7: 124-140, 2011
C.Møntergaard, H.M.F.Tulk, L.Lauritzen, T.Tholstrup, & L.E.Robinson: Acute ingestion of long-chain n-3 polyunsaturated fatty acids decreases fibrinolysis in men with metabolic syndrome. J. Nutr. 140: 38-43, 2010
C.Giewerckman, L.B.Halkjaer, S.M.Jensen, L.Lauritzen, & H.Bisgaard: Increased Risk of Eczema but Reduced Risk of Wheezy Disorder from Exclusive Breast Feeding in High-Risk Infants. JACI 125: 866-871, 2010
M.H.Pedersen, C.Mølgaard, L.I.Hellgren, & L.Lauritzen*: Effect of fish oil supplementation on markers of the metabolic syndrome (in adolescent boys). J. Pediatr. 157: 395-400, 2010
J.Hallund, B.M.Overgaard, S.H.Bügel, C.Jacobsen, J.Jakobsen, H.Krarup, J.Holm, H.Hauch Nielsen, & L.Lauritzen*: The effect of farmed trout on cardiovascular risk markers in healthy men. Br. J. Nutr. 104: 1528-1536. 2010
C.T.Damsgaard, L.Lauritzen, P.C.Calder, T.M.R.Kjær, & H.Frøkiær: Whole-blood culture is a suitable low-cost method to measure monocytic cytokines – A comparison of cytokine production in cultures of human whole-blood, mononuclear cells and monocytes. J. Immun. Methods 340: 95-101, 2009
M.Asserhøj, A.S.Nehammer, J.Matthiessen, K.F.Michaelsen, & L.Lauritzen*: Maternal Fish Oil-Supplementation during Lactation May Adversely Affect Long-Term Blood Pressure, Energy Intake and Physical Activity of 7 y old Boys. J. Nutr. 139: 298-304, 2009
C.T.Damsgaard, L.Lauritzen, P.C.Calder, T.R.Kjær, & H.Frøkiær: Reduced ex Vivo Interleukin-6 Production by Dietary Fish Oil Is Not Modified by Linoleic Acid Intake in Healthy Men. J. Nutr. 139: 1410-1414, 2009
K.F.Michaelsen, C.Hoppe, N.Roos, P.Kæstel, M.Stougaard, L.Lauritzen, C.Mølgaard, T.Girma, & H.Friis: Choice of foods and ingredients to give to moderately malnourished children 6 months to 5 years. Food Nutr. Bull. 30: S343-404, 2009
J.Overgaard, T.Porsgaard, Z.Guo, L.Lauritzen, & H.Mu: Postprandial lipid responses of butter blend containing fish oil in a single-meal study in humans. Mol. Nutr. Food Res. 52(10): 1140-1146, 2008
L.Lauritzen*, J.H.Christensen, C.T.Damsgaard & K.F.Michaelsen: The Effect of Fish Oil Supplementation on Heart Rate in Healthy Danish Infants. Ped. Res. 64: 610-614, 2008
C.T.Damsgaard, H.Frøkiær, A.D.Andersen, & L.Lauritzen: Combined effects of fish oil and high or low linoleic acid intake on cardiovascular risk markers in healthy men. J. Nutr. 138: 1061–1066, 2008
S.Bartelt, M.Timm, C.T.Damsgaard, E.Wind, H.S.Hansen, & L.Lauritzen*: The effect of dietary fish oil-supplementation to healthy young men on oxidative burst measured by whole blood chemiluminescence. Br. J. Nutr. 99: 1230-1238, 2008
C.T.Damsgaard*, H.Frøkiær, & L.Lauritzen*: Combined effects of fish oil supplementation and dietary PUFA intake on tissue fatty acid composition. Br. J. Nutr. 99: 147-154, 2008
C.T.Damsgaard, L.Lauritzen, T.M.R.Kjær, P.M.I.Holm, M.B.Fruekilde, K.F.Michaelsen, & H.Frøkiær: Fish Oil and Immune Function in Healthy Infants: An Intervention Study. J. Nutr. 137: 1031-1036, 2007
S.Nielsen, D.S.Nielsen, L.Lauritzen, M.Jakobsen, & K.F.Michaelsen: Impact of diet on the intestinal microbiota in 10-month-old infants. J. Pediatr. Gastroenterol. Nutr. 44: 613-618, 2007
L.Lauritzen*, L.Brydensholt Halkjær, T.B.Mikkelsen, S.F.Olsen, K.F.Michaelsen, L.Loland, & H.Bisgaard: Fatty acid composition of human milk in atopic Danish mothers. Am. J. Clin. Nutr. 84: 190-196, 2006
A.Larnkjær, J.H.Christensen, K.F.Michaelsen, & L.Lauritzen*: Blood pressure and heart rate variability in children 2 years after fish oil supplementation of their lactating mothers. J. Nutr. 136: 1539-1544, 2006
E.M.Straarup, L.Lauritzen*, J.Færch, & K.F.Michaelsen: The stereospecific triacylglycerol structures and fatty acid profiles of human milk fat and fat in infant formulas. J. Ped. Gastroenterol. Nutr. 42: 293-299, 2006
C.T.Damsgaard, L.Schack-Nielsen, O.Hels, K.F.Michaelsen, M.B. Fruekilde, & L.Lauritzen: The effects of fish oil supplementation on blood pressure and lipid profile in late infancy. J. Nutr. 136: 94-99, 2006
M.H.Jørgensen, P.K.Nielsen, K.F.Michaelsen, P.Lund, & L.Lauritzen*: The relationship between long-chain polyunsaturated fatty acids in breast-milk, maternal and infant erythrocytes during the first four months of lactation. Maternal Child Nutr. 2: 29-39, 2006
L.Lauritzen*, M.H.Jørgensen, S.F.Olsen, E.M.Straarup, & K.F.Michaelsen: Maternal fish oil upplementation in lactation: Effect on problem solving and language development. Reprod. Nutr. Dev. 45: 535-547, 2005
L.Lauritzen*, T.M.R.Kjær, M.B.Fruekilde, K.F.Michaelsen, & H.Frøkiær: Fish oil supplementation of lactating mothers affects cytokine production in 2½-year-old children. Lipids 40: 669-676, 2005
L.Lauritzen*, C.Hoppe, E.M.Straarup, & K.F.Michaelsen: Maternal fish oil supplementation in lactation and growth during the first 2.5 years of life. Ped. Res. 58: 235-242, 2005
C.Hoppe, T.R.Udam, L.Lauritzen, A.Juul, C.Mølgaard, & K.F.Michaelsen: Animal protein intake, s-IGF-1 and growth in healthy 2½ year old children. Am. J. Clin. Nutr. 80: 447-452, 2004
L.Lauritzen*, M.H.Jørgensen, T.B.Schow, I.M.Skovgaard, E.M.Straarup, S.F.Olsen, C.E.Høy, & K.F.Michaelsen: Maternal fish oil supplementation during lactation: Effect on visual acuity and n-3 fatty acid content of infant erythrocytes. Lipids 39: 195-206, 2004
J.Ulbak, L.Lauritzen*, H.S.Hansen, & K.F.Michaelsen: Diet and blood pressure in 2.5-y-old Danish children. Am. J. Clin. Nutr. 79: 1095-1102, 2004
L.Lauritzen*, M.H.Jørgensen, & K.F.Michaelsen: Test-retest reliability of swept visual evolved potential measurements of infant visual acuity and contrast sensitivity. Ped. Res. 55: 701-708, 2004
L.Lauritzen* & H.S.Hansen: Which of the n-3 fatty acids should be called essential? Lipids 38: 805-811, 2003
K.F.Michaelsen, L.Lauritzen, M.H.Jørgensen, & E.L.Mortensen: Breast-feeding and brain development. Scand. J. Nutr. 47: 147-151, 2003
L.Lauritzen*, M.H.Jørgensen, H.S.Hansen, & K.F.Michaelsen: Fluctuations in human milk long-chain PUFA levels in relation to dietary fish intake. Lipids 37: 237-244, 2002
L.Lauritzen*, H.S.Hansen, M.H.Jørgensen, & K.F.Michaelsen: The essentiality of long-chain n-3 fatty acids in relation to the development and function of the brain and retina. Prog. Lipid Res. 40: 1-94, 2001

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